Dietary chokeberry and dried jujube fruit attenuates high-fat and high-fructose diet-induced dyslipidemia and insulin resistance via activation of the IRS-1/PI3K/Akt pathway in C57BL/6 J mice [0.03%]
饮食性沙棘和干燥的大枣果实通过激活IRS-1 / PI3K / Akt途径缓解C57BL / 6J小鼠高脂和高果糖诱导的血脂异常和胰岛素抵抗
Oeuk Jeong,Hyun-Sook Kim
Oeuk Jeong
Background: The incidence of metabolic syndrome linked to dyslipidemia and insulin resistance has increased; thus, studies must be conducted to elucidate this phenomenon. The present study aimed to investigate the protect...
A high-fat diet induces rapid changes in the mouse hypothalamic proteome [0.03%]
高脂饮食可快速诱导小鼠下丘脑蛋白质组变化
Fiona H McLean,Fiona M Campbell,Rosamund F Langston et al.
Fiona H McLean et al.
Background: Prolonged over-consumption of a high-fat diet (HFD) commonly leads to obesity and insulin resistance. However, even 3 days of HFD consumption has been linked to inflammation within the key homeostatic brain re...
Xiao-Rong Zhu,Fang-Yuan Yang,Jing Lu et al.
Xiao-Rong Zhu et al.
Background: Proliferative diabetic retinopathy (PDR), a sight-threatening retinopathy, is the leading cause of irreversible blindness in adults. Despite strict control of systemic risk factors, a fraction of patients with...
High-density lipoprotein ameliorates palmitic acid-induced lipotoxicity and oxidative dysfunction in H9c2 cardiomyoblast cells via ROS suppression [0.03%]
高密度脂蛋白通过抑制ROS改善棕榈酸诱导的H9c2心肌细胞脂毒性及氧化功能障碍
Kuen-Ming Wu,Yuan-Man Hsu,Mei-Chin Ying et al.
Kuen-Ming Wu et al.
Background: High levels circulating saturated fatty acids are associated with diabetes, obesity and hyperlipidemia. In heart, the accumulation of saturated fatty acids has been determined to play a role in the development...
Parental overweight and hypertension are associated with their children's blood pressure [0.03%]
父母超重和高血压与子女的血压有关
Renying Xu,Xiaomin Zhang,Yiquan Zhou et al.
Renying Xu et al.
Background: We evaluated the association between parental factors (overweight, history of hypertension, and education level) and children's blood pressure status. Further, we evaluated to what extent the potential associa...
Whole blueberry protects pancreatic beta-cells in diet-induced obese mouse [0.03%]
whole blueberry保护饮食诱导的肥胖小鼠胰腺β细胞
Weixiang Liu,Yiping Mao,Jacob Schoenborn et al.
Weixiang Liu et al.
Background: Blueberry is rich in bioactive substances and possesses powerful antioxidant potential, which can protect against oxidant-induced and inflammatory cell damage and cytotoxicity. The aim of this study was to det...
Dietary compounds and cutaneous malignant melanoma: recent advances from a biological perspective [0.03%]
从生物学角度浅析饮食化合物与皮肤恶性黑色素瘤的最新研究进展
Maria Neve Ombra,Panagiotis Paliogiannis,Luigia Stefania Stucci et al.
Maria Neve Ombra et al.
Cutaneous malignant melanoma is a heterogeneous disease, being the consequence of specific genetic alterations along several molecular pathways. Despite the increased knowledge about the biology and pathogenesis of melanoma, the incidence h...
Placental extract suppresses differentiation of 3T3-L1 preadipocytes to mature adipocytes via accelerated activation of p38 MAPK during the early phase of adipogenesis [0.03%]
胎盘提取物通过在脂肪细胞生成早期阶段加速活化p38 MAPK来抑制3T3-L1前脂肪细胞向成熟脂肪细胞的分化
Yusuke Ando,Fumiaki Sato,Hazuki Fukunaga et al.
Yusuke Ando et al.
Background: Adipogenesis, the process of preadipocyte differentiation to mature adipocytes accompanied by accumulation of intracytoplasmic lipid droplets, is regulated by various genetic and environmental factors, and clo...
Seon-Jeong Lee,Su-Jung Cho,Eun-Young Kwon et al.
Seon-Jeong Lee et al.
Background: Obesity increases the risk of metabolic dysfunction such as dyslipidemia, hypertension, and fatty liver. Physcion (PY) is an anthraquinone that reportedly has anti-inflammatory and anti-bacterial properties. H...
Iron deficiency in late pregnancy and its associations with birth outcomes in Chinese pregnant women: a retrospective cohort study [0.03%]
中国孕妇妊娠晚期缺铁状况及其对出生结局影响的队列研究
Xiaosong Yuan,Huiwen Hu,Ming Zhang et al.
Xiaosong Yuan et al.
Background: Several biomarkers are used to measure iron deficiency (ID) during pregnancy, but the prevalence of ID and its association with adverse birth outcomes shows inconsistent results. The aim of this study was to e...