Milk exosomal miRNAs: potential drivers of AMPK-to-mTORC1 switching in β-cell de-differentiation of type 2 diabetes mellitus [0.03%]
牛奶外泌体miRNA：潜在的2型糖尿病β细胞去分化中AMPK到mTORC1转换驱动因素
Bodo C Melnik
Bodo C Melnik
Type 2 diabetes mellitus (T2DM) steadily increases in prevalence since the 1950's, the period of widespread distribution of refrigerated pasteurized cow's milk. Whereas breastfeeding protects against the development of T2DM in later life, a...
A maple syrup extract alters lipid metabolism in obese type 2 diabetic model mice [0.03%]
从肥胖的2型糖尿病模型小鼠中提取的枫糖浆改变了脂质代谢
Tsudoi Toyoda,Asuka Kamei,Tomoko Ishijima et al.
Tsudoi Toyoda et al.
Background: Some polyphenols are known to improve the symptoms of diabetes. In the present study, we investigated the effects of a polyphenol-rich extract of maple syrup (MSx) on a diabetic mouse model. ...
The association of dietary macronutrients with anthropometric changes, using iso-energetic substitution models: Tehran lipid and glucose study [0.03%]
同能量膳食宏量营养素替代模型与体格指标变化关联的横断面和队列研究：特兰斯脂肪糖研究
Firoozeh Hosseini-Esfahani,Glareh Koochakpoor,Parvin Mirmiran et al.
Firoozeh Hosseini-Esfahani et al.
Background: The consequences of optimal dietary macronutrient compositions especially quality of proteins on weight gain still remain controversial. The aim of the current study was to evaluate the iso-energetic substitut...
Inhibition of androgen receptor can decrease fat metabolism by decreasing carnitine palmitoyltransferase I levels in skeletal muscles of trained mice [0.03%]
雄激素受体抑制通过降低训练小鼠骨骼肌 carnitine palmitoyltransferase I 水平来减少脂肪代谢
Jisu Kim,Jonghoon Park,Nahyun Kim et al.
Jisu Kim et al.
Background: Androgen hormone levels are strongly associated with obesity in adult mammals, especially with advanced age. We investigated androgen receptor inhibition on fat metabolism and long-chain fatty acid (LCFA) tran...
Alicja Pakiet,Agnieszka Jakubiak,Aleksandra Czumaj et al.
Alicja Pakiet et al.
Background: The appropriate fatty acids composition of brain lipids is critical for functioning of this organ. The alterations of brain fatty acids composition may lead to neurological and neurodegenerative diseases. ...
Plasma concentration of interleukin-6 was upregulated in cancer cachexia patients and was positively correlated with plasma free fatty acid in female patients [0.03%]
癌症恶病质患者血浆中IL-6水平升高且与女患者中游离脂肪酸呈正相关
Jun Han,Chaocheng Lu,Qingyang Meng et al.
Jun Han et al.
Background: Cancer cachexia is a clinical manifestation in various advanced cancers that characterized by muscle atrophy and fat loss as its main features; it is frequently associated with systemic inflammatory response. ...
Curcumin prevents high-fat diet-induced hepatic steatosis in ApoE-/- mice by improving intestinal barrier function and reducing endotoxin and liver TLR4/NF-κB inflammation [0.03%]
姜黄素通过改善肠道屏障功能和减少内毒素以及肝TLR4/NF-κB炎症反应减轻ApoE基因敲除小鼠高脂饮食诱导的非酒精性脂肪肝病
Dan Feng,Jun Zou,Dongfang Su et al.
Dan Feng et al.
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and has become a public health concern worldwide. The hallmark of NAFLD is hepatic steatosis. Therefore, there is an urgent ne...
Associations of dairy and fiber intake with circulating odd-chain fatty acids in post-myocardial infarction patients [0.03%]
冠心病后患者的膳食乳制品和纤维素摄入与血液中奇数链脂肪酸的水平之间的关系
Kamalita Pertiwi,Leanne K Küpers,Anne J Wanders et al.
Kamalita Pertiwi et al.
Background: Circulating odd-chain fatty acids pentadecanoic (15:0) and heptadecanoic acid (17:0) are considered to reflect dairy intake. In cohort studies, higher circulating 15:0 and 17:0 were associated with lower type ...
Higher glycolytic capacities in muscle of carnivorous rainbow trout juveniles after high dietary carbohydrate stimulus at first feeding [0.03%]
以肉食性虹鳟鱼苗为材料的研究：投喂高碳水化合物日粮对其肌肉糖酵解能力的影响
Yan Song,Hélène Alami-Durante,Sandrine Skiba-Cassy et al.
Yan Song et al.
Background: Rainbow trout is a "glucose-intolerant" carnivorous species. Using the metabolic programming strategy, we used early nutritional stimuli in order to modify carbohydrate utilization in trout juveniles. ...
Impact of 3-year changes in fasting insulin and insulin resistance indices on incident hypertension: Tehran lipid and glucose study [0.03%]
Tehran Lipid and Glucose Study三项胰岛素及胰岛素抵抗指标变化对新发高血压影响的队列研究
Aidin Baghbani-Oskouei,Maryam Tohidi,Mitra Hasheminia et al.
Aidin Baghbani-Oskouei et al.
Background: To examine the association between changes in fasting insulin, homeostasis model assessment of insulin resistance (HOMA-IR), and insulin-glucose ratio (IGR) levels, over approximately 3 years with incident hyp...