Discovery of metabolic biomarkers for gestational diabetes mellitus in a Chinese population [0.03%]
在中国人群中发现妊娠糖尿病的代谢生物标志物
Wenqian Lu,Mingjuan Luo,Xiangnan Fang et al.
Wenqian Lu et al.
Background: Gestational diabetes mellitus (GDM), one of the most common pregnancy complications, can lead to morbidity and mortality in both the mother and the infant. Metabolomics has provided new insights into the patho...
Association between hypertension and coffee drinking based on CYP1A2 rs762551 single nucleotide polymorphism in Taiwanese [0.03%]
基于台湾人CYP1A2基因多态性高血压与饮咖啡关系的研究
Chien-Chou Hou,Disline Manli Tantoh,Chuan-Chao Lin et al.
Chien-Chou Hou et al.
Background: Hypertension increases the likelihood of cardiovascular diseases (CVDs). Cytochrome P450 1A2 (CYP1A2) single nucleotide polymorphism (SNP) is related to caffeine metabolism and the risk of CVD among coffee dri...
Anti-inflammatory and -apoptotic effects of a long-term herbal extract treatment on DSS-induced colitis in mice fed with high AGEs-fat diet [0.03%]
长期草药提取物治疗对高AGEs脂肪饮食喂养的小鼠DSS诱导结肠炎的抗炎和抗凋亡作用
Fatemeh Azizian-Farsani,Marcin Osuchowski,Navid Abedpoor et al.
Fatemeh Azizian-Farsani et al.
Background: Obesity is associated with many comorbidities including inflammatory bowel disease (IBD). We investigated prophylactic effects of an herbal extract (HE) on the DSS-induced colitis mice challenged with high AGE...
Metabolomics and physiological analysis of the effect of calcium supplements on reducing bone loss in ovariectomized rats by increasing estradiol levels [0.03%]
代谢组学和生理分析：通过增加雌二醇水平减轻卵巢切除大鼠骨质流失的钙补充剂的作用
Hongmei Mao,Wenjun Wang,Lili Shi et al.
Hongmei Mao et al.
Background: Data from the 2010-2012 Chinese National Nutrition and Health Survey showed that the vast majority of postmenopausal women in China had dual deficiencies in calcium and estrogen. ...
Modulation and bioinformatics screening of hepatic mRNA-lncRNAs (HML) network associated with insulin resistance in prediabetic and exercised mice [0.03%]
与糖尿病前期和运动小鼠胰岛素抵抗相关的肝mRNA-lncRNAs（HML）网络的调控及生物信息学筛选
Fatemeh Kazeminasab,Sayed Mohammad Marandi,Maryam Baharlooie et al.
Fatemeh Kazeminasab et al.
Background: Insulin resistance is associated with prediabetes and further progression to type 2 diabetes mellitus (T2DM). This study aims to investigate novel hepatic lncRNAs associated with key genes in insulin resistanc...
Calcium channel blockers do not protect against saturated fatty acid-induced ER stress and apoptosis in human pancreatic β-cells [0.03%]
钙通道阻滞剂不能保护饱和脂肪酸诱导的胰岛β细胞内质网应激和凋亡
Jan Šrámek,Vlasta Němcová,Jan Kovář
Jan Šrámek
It was evidenced that saturated fatty acids (FAs) have a detrimental effect on pancreatic β-cells function and survival, leading to endoplasmic reticulum (ER) calcium release, ER stress, and apoptosis. In the present study, we have tested ...
Dietary habits and the presence and degree of asymptomatic diverticular disease by magnetic resonance imaging in a Western population: a population-based cohort study [0.03%]
西方人群中磁共振成像显示无症状憩室病的存在和程度与饮食习惯的关系：基于人群的队列研究
Esther Askani,Susanne Rospleszcz,Theresa Rothenbacher et al.
Esther Askani et al.
Background: Despite the worldwide burden of diverticular disease, the connections between diverticular disease and dietary habits remain poorly understood, particularly in an asymptomatic representative sample. We investi...
The impact of gut microbiota metabolites on cellular bioenergetics and cardiometabolic health [0.03%]
肠道微生物代谢产物对细胞生物能量和心血管代谢健康的影响
Lenka Tomasova,Marian Grman,Karol Ondrias et al.
Lenka Tomasova et al.
Recent research demonstrates a reciprocal relationship between gut microbiota-derived metabolites and the host in controlling the energy homeostasis in mammals. On the one hand, to thrive, gut bacteria exploit nutrients digested by the host...
Asiatic acid alleviates Ang-II induced cardiac hypertrophy and fibrosis via miR-126/PIK3R2 signaling [0.03%]
乌术酸通过miR-126/PIK3R2信号缓解Ang-II诱导的心脏肥大和纤维化
Haiyu Li,Xiaoxu Tian,Yongjuan Ruan et al.
Haiyu Li et al.
Background: Cardiac hypertrophy is an independent risk factor of many cardiovascular diseases. Studies have demonstrated that microRNA-126 (miR-126) was involved in angiogenesis during physiological and pathological proce...
Association between frequency of spicy food consumption and hypertension: a cross-sectional study in Zhejiang Province, China [0.03%]
中国浙江省饮食辛辣食物频率与高血压的关联：一项横断面研究
Hao Wang,Lingli Chen,Dun Shen et al.
Hao Wang et al.
Background: Hypertension is a known risk factor for multiple chronic diseases. Existing literature on the association between frequency of spicy food consumption and hypertension shows mixed findings. ...