Risk of subclinical atherosclerosis across metabolic transition in individuals with or without fatty liver disease: a prospective cohort study [0.03%]
代谢过渡过程中或伴有脂肪肝疾病的个体亚临床动脉粥样硬化风险：一项前瞻性队列研究
Zhuojun Xin,Jiaojiao Huang,Qiuyu Cao et al.
Zhuojun Xin et al.
Background: Metabolic dysfunction is a major determinant in the progression of fatty liver disease. It is pivotal to evaluate the metabolic status and subsequent transition in fatty liver population and to identify the ri...
Different associations of general and abdominal obesity with upper and lower extremity artery disease among a community population in China [0.03%]
中国社区人群中全身性和腹部肥胖与上下肢动脉硬化性疾病的关系研究
Yong Wang,Xiaoyan Guo,Yi Zhang et al.
Yong Wang et al.
Background: The associations between obesity and abnormalities of upper and lower extremity arteries remain to be elucidated. This study is aimed to investigate whether general obesity and abdominal obesity are associated...
Weight cycling based on altered immune microenvironment as a result of metaflammation [0.03%]
基于元炎症引起的免疫微环境改变的体重波动
Wanyang Li,Wei Chen
Wanyang Li
As a result of the obesity epidemic, more people are concerned about losing weight; however, weight regain is common, leading to repeated weight loss and weight cycling. The health benefits of early weight loss are nullified by weight regai...
Lipidomic analysis of brain and hippocampus from mice fed with high-fat diet and treated with fecal microbiota transplantation [0.03%]
高脂饮食小鼠粪菌移植后的脑和海马体的脂质组分析
Jinchen Li,Hongying Huang,Rong Fan et al.
Jinchen Li et al.
Background: Dietary fat intake affects brain composition and function. Different types of dietary fatty acids alter species and abundance of brain lipids in mice. The aim of this study is to explore whether the changes ar...
The effect of DASH diet on glycemic response, meta-inflammation and serum LPS in obese patients with NAFLD: a double-blind controlled randomized clinical trial [0.03%]
一种减肥食谱对肥胖型非酒精性脂肪肝病患者糖代谢、元炎症和血清LPS影响的双盲随机对照试验
Farnaz Rooholahzadegan,Sara Arefhosseini,Helda Tutunchi et al.
Farnaz Rooholahzadegan et al.
Background: As dietary approaches to stop hypertension (DASH) dietary pattern has been shown to be effective in hypertension and obesity, the present study investigated the effects of following DASH diet on glycemic, meta...
A transdermal treatment with MC903 ameliorates diet-induced obesity by reducing visceral fat and increasing myofiber thickness and energy consumption in mice [0.03%]
MC903经皮治疗通过减少内脏脂肪和增加肌肉厚度及能量消耗来改善小鼠饮食诱导的肥胖症状
Tsutomu Wada,Yuichiro Miyazawa,Misa Ikurumi et al.
Tsutomu Wada et al.
Aim: MC903 is a synthetic derivative of vitamin D3 that has been designed to diminish its impact on calcium metabolism and is clinically used as a transdermal reagent for psoriasis. Animal studies showed that an oral or i...
Gastrodin ameliorates atherosclerosis by inhibiting foam cells formation and inflammation through down-regulating NF-κB pathway [0.03%]
姜半夏苷通过下调NF-κB信号通路抑制泡沫细胞形成和炎症反应从而改善动脉粥样硬化病变
Xiaofei Xue,Fulei Li,Mengke Xu et al.
Xiaofei Xue et al.
Background: Gastrodin is an effective polyphenol extracted from Chinese natural herbal Gastrodiae elata Blume, which exhibits antioxidant and anti-inflammatory effects. It has been reported to benefit neurodegenerative di...
Heterogeneous effects of individual high-fat diet compositions on phenotype, metabolic outcome, and hepatic proteome signature in BL/6 male mice [0.03%]
高脂膳食对C57BL/6雄性小鼠表型、代谢结局及肝脏蛋白质组特征异质影响的组成效应
Ruth Janoschek,Marion Handwerk,Eva Hucklenbruch-Rother et al.
Ruth Janoschek et al.
The multitude of obesogenic diets used in rodent studies can hardly be overviewed. Since standardization is missing and assuming that individual compositions provoke individual effects, the choice of quality, quantity and combination of die...
Association of plasma lipid metabolism profiles with overall survival for patients with gastric cancer undergoing gastrectomy based on 1H-NMR spectroscopy [0.03%]
基于¹H-NMR光谱的胃癌根治术后患者血浆脂质代谢特征与生存期的关系分析
Yaopeng Qiu,Zhou Xu,Qingfeng Xie et al.
Yaopeng Qiu et al.
Background: Lipid metabolism dysregulation is a prominent metabolic alteration in various cancers. The study aimed to explore the association of plasma lipid metabolism profiles with overall survival (OS) for gastric canc...
Chondroitin sulfate alleviates osteoporosis caused by calcium deficiency by regulating lipid metabolism [0.03%]
硫酸软骨素通过调节脂质代谢缓解钙缺乏引起的骨质疏松症
Tianshu Liu,Hai Yu,Shuai Wang et al.
Tianshu Liu et al.
The use of non-drug intervention for calcium deficiency has attracted attention in recent years. Although calcium carbonate is the preferred raw material for calcium supplementation, there are few reports on the mechanism of the combined ac...