Does dietary nitrate boost the effects of caloric restriction on brain health? Potential physiological mechanisms and implications for future research [0.03%]
膳食硝酸盐能否增强节食对大脑健康的影响？潜在的生理机制及对未来研究的意义
Mushari Alharbi,Blossom Cm Stephan,Oliver M Shannon et al.
Mushari Alharbi et al.
Dementia is a highly prevalent and costly disease characterised by deterioration of cognitive and physical capacity due to changes in brain function and structure. Given the absence of effective treatment options for dementia, dietary and o...
Differential effects of plant-based flours on metabolic homeostasis and the gut microbiota in high-fat fed rats [0.03%]
基于植物的面糊通过不同的机制改善高脂饮食喂养大鼠的代谢稳态和肠道菌群失调
Taylor M Martinez,Hallie R Wachsmuth,Rachel K Meyer et al.
Taylor M Martinez et al.
Background: The gut microbiome is a salient contributor to the development of obesity, and diet is the greatest modifier of the gut microbiome, which highlights the need to better understand how specific diets alter the g...
New insights into the nutritional genomics of adult-onset riboflavin-responsive diseases [0.03%]
成人发病的核黄素反应性疾病营养基因组学的新见解
Chiara Murgia,Ankush Dehlia,Mark A Guthridge
Chiara Murgia
Riboflavin, or vitamin B2, is an essential nutrient that serves as a precursor to flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN). The binding of the FAD and/or FMN cofactors to flavoproteins is critical for regulating the...
The effect of the modified fat-protein unit algorithm compared with that of carbohydrate counting on postprandial glucose in adults with type-1 diabetes when consuming meals with differing macronutrient compositions: a randomized crossover trial [0.03%]
一种针对1型糖尿病成人饮食中宏量营养成分不同的餐食对餐后血糖影响的改良脂肪蛋白质当量算法与碳水化合物计算法比较的随机交叉试验
Yunying Cai,Mengge Li,Lun Zhang et al.
Yunying Cai et al.
Background: The optimization of glucose control in type-1 diabetes is challenged by postprandial glycemic variability. This study aimed to compare the postprandial glycemic effects of carbohydrate counting and the modifie...
Prospective association between an obesogenic dietary pattern in early adolescence and metabolomics derived and traditional cardiometabolic risk scores in adolescents and young adults from the ALSPAC cohort [0.03%]
来自ALSPAC队列的青少年和年轻成人中的促肥胖饮食模式与代谢组学衍生的传统心血管代际风险评分的相关性研究
Eduard Martínez Solsona,Laura Johnson,Kate Northstone et al.
Eduard Martínez Solsona et al.
Background: Dietary intake during early life may be a modifying factor for cardiometabolic risk (CMR). Metabolomic profiling may enable more precise identification of CMR in adolescence than traditional CMR scores. We aim...
METTL3 exacerbates insulin resistance in hepatocytes by regulating m6A modification of cytochrome P450 2B6 [0.03%]
METTL3通过调节细胞色素P450 2B6的m6A修饰加重肝细胞胰岛素抵抗
Yongqing Li,Dantong Zhang,Yinan Gao et al.
Yongqing Li et al.
Background: Insulin resistance (IR) in hepatocytes endangers human health, and frequently results in the development of non-alcoholic fatty liver disease (NAFLD). Research on m6A methylation of RNA molecules has gained po...
The association between dietary quality scores with C-reactive protein and novel biomarkers of inflammation platelet-activating factor and lipoprotein-associated phospholipase A2: a cross-sectional study [0.03%]
饮食质量评分与C反应蛋白和新型炎症生物标志物磷脂酶A2和血小板活化因子的关联：横断面研究
Carolyn J English,Anna E Lohning,Hannah L Mayr et al.
Carolyn J English et al.
Healthy dietary patterns are associated with lower inflammation and cardiovascular disease (CVD) risk and adherence can be measured using diet quality scores. Inflammation is traditionally measured with C-reactive protein (hsCRP), however t...
Effect of weight change on the association between overall and source of carbohydrate intake and risk of metabolic syndrome: Tehran lipid and glucose study [0.03%]
体重变化对整体及来源的碳水化合物摄入与代谢综合征风险关联的影响：泰伦平脂糖研究
Somayeh Hosseinpour-Niazi,Bahar Bakhshi,Parvin Mirmiran et al.
Somayeh Hosseinpour-Niazi et al.
Background: In this prospective cohort study, we aimed to evaluate the association between dietary carbohydrates, whole grains, refined grains, and simple sugar with the risk of metabolic syndrome (MetS) and assess the ef...
The impact of macrosomia on cardiometabolic health in preteens: findings from the ROLO longitudinal birth cohort study [0.03%]
巨婴对学龄前儿童的心血管代谢健康的影响：ROLO出生队列研究的结果
Sophie Callanan,Sarah Louise Killeen,Anna Delahunt et al.
Sophie Callanan et al.
Background: Macrosomia (birthweight ≥ 4 kg or ≥ 4.5 kg) is strongly associated with a predisposition to childhood obesity, which in turn is linked with adverse cardiometabolic health. Despite this, there is a lack of lo...
Associations of starchy and non-starchy vegetables with risk of metabolic syndrome: evidence from the NHANES 1999-2018 [0.03%]
1999-2018年NHANES数据中蔬菜摄入与代谢综合征风险的关系分析
Yingrui Li,Bingquan Xiong,Min Zhu et al.
Yingrui Li et al.
Background: Higher dietary quality, including increased vegetable consumption, was associated with a reduced risk of metabolic syndrome (MetS). However, specific vegetable consumption in the development of MetS remains ob...