Hormone replacement therapy and thrombotic risk: beauty is only skin deep [0.03%]
激素替代疗法与凝血风险：美只是一时的
Frits R Rosendaal
Frits R Rosendaal
In their meta-analysis of studies on hormone replacement therapy (HRT), Canonico and colleagues reported that the risk of venous thrombosis was increased by 2.5-fold in current users of oral preparations, while the risk was not increased in...
APOA5 genetic variants are markers for classic hyperlipoproteinemia phenotypes and hypertriglyceridemia [0.03%]
APOA5基因变异是经典高脂蛋白血症表型和高甘油三酯血症的标志物
Jian Wang,Matthew R Ban,Brooke A Kennedy et al.
Jian Wang et al.
Background: Several known candidate gene variants are useful markers for diagnosing hyperlipoproteinemia. In an attempt to identify other useful variants, we evaluated the association of two common APOA5 single-nucleotide...
Joseph S Alpert,Kristian Thygesen,Harvey D White et al.
Joseph S Alpert et al.
The original WHO definition of myocardial infarction (MI) was revised in 2000 and further refined in 2007. Central to the new universal definition of MI was the use of the highly sensitive and specific biomarker troponin. In the investigati...
Hideo Mitamura
Hideo Mitamura
Can functional performance be used as a simple prognostic indicator in peripheral arterial disease? [0.03%]
功能性能能否作为外周动脉疾病的一个简单预测指标？
Jeffrey W Olin
Jeffrey W Olin
McDermott et al. have demonstrated, for the first time, that a poor 6 min walk performance and slow walking speed in patients with peripheral arterial disease (PAD) are predictors of increased all-cause and cardiovascular mortality. The ass...
Risk stratification in acute decompensated heart failure: the role of cardiac troponin [0.03%]
急性心力衰竭的危险分层：心脏肌钙蛋白的作用
Christian Mueller
Christian Mueller
Cardiac troponins provide important prognostic information in patients with acute decompensated heart failure. In a large study by the ADHERE Investigators, 6.2% of 67,924 patients with acute decompensated heart failure were positive for ca...
Vascular aging: insights from studies on cellular senescence, stem cell aging, and progeroid syndromes [0.03%]
血管衰老：来自细胞衰老、干细胞衰老和早衰综合征的研究启示
Tohru Minamino,Issei Komuro
Tohru Minamino
Epidemiological studies have shown that age is the chief risk factor for atherosclerotic cardiovascular diseases, but the molecular mechanisms that underlie the increase in risk conferred by aging remain unclear. Evidence suggests that the ...
Caterina Simon,Fabio Capuano,Antonino Roscitano et al.
Caterina Simon et al.
Background: A 70-year-old man with diabetes mellitus, fever of unknown origin and oliguria was admitted to hospital. Blood cultures were positive for a Staphylococcus aureus infection and antibiotic therapy was started. A...
Da-Yi Hu,Yi-Fang Guo
Da-Yi Hu
Randomized, controlled trial of intramuscular or intracoronary injection of autologous bone marrow cells into scarred myocardium during CABG versus CABG alone [0.03%]
自体骨髓细胞冠状动脉旁路移植术中瘢痕心肌的随机对照试验：肌肉内或冠状动脉注射与单独冠状动脉旁路移植术的比较
Keng-Leong Ang,Derek Chin,Francisco Leyva et al.
Keng-Leong Ang et al.
Background: Studies of the transplantation of autologous bone marrow cells (BMCs) in patients with chronic ischemic heart disease have assessed effects on viable, peri-infarct tissue. We conducted a single-blinded, random...
Randomized Controlled Trial
Nature clinical practice. Cardiovascular medicine. 2008 Oct;5(10):663-70. DOI:10.1038/ncpcardio1321 2008