Fixed-dose combination therapy and secondary cardiovascular prevention: rationale, selection of drugs and target population [0.03%]
固定剂量复方疗法与二级心血管疾病预防：理论依据、药物选择及目标人群分析
Ginés Sanz,Valentin Fuster
Ginés Sanz
Ischemic heart disease and stroke are the leading causes of death worldwide. A large proportion of individuals at high 10-year risk of a cardiovascular event live in low-income and middle-income countries, and the large majority of all card...
Issues to consider in the pharmaceutical development of a cardiovascular polypill [0.03%]
心血管多药片的药物开发需要注意的问题
Antonio Guglietta,Marta Guerrero
Antonio Guglietta
The pharmaceutical development of a cardiovascular polypill presents several unique challenges. The selection of the type and number of active drugs to be incorporated requires important consideration of clinical, pharmaceutical and commerc...
Mpiko Ntsekhe,Bongani M Mayosi
Mpiko Ntsekhe
The pericardium, myocardium, coronary arteries and pulmonary arteries are the main targets for cardiac disease in people who are infected with HIV. Geography and access to highly active anti-retroviral therapy (HAART) have a major influence...
The need to test the theories behind the Polypill: rationale behind the Indian Polycap Study [0.03%]
对波利佩尔理论进行检验的必要性——印度多项制剂研究的设计依据
Denis Xavier,Prem Pais,Alben Sigamani et al.
Denis Xavier et al.
Randomized Controlled Trial
Nature clinical practice. Cardiovascular medicine. 2009 Feb;6(2):96-7. DOI:10.1038/ncpcardio1438 2009
A case of coronary artery fistula visualized by 64-slice multidetector CT [0.03%]
一例冠状动脉瘘的64层螺旋CT血管成像诊断
Francesco Versaci,Costantino Del Giudice,Massimiliano Sperandio et al.
Francesco Versaci et al.
Background: A 27-year-old woman was admitted to hospital with a 1-year history of mild dyspnea. Investigations: Physical examination, c...
Michael E Farkouh,Valentin Fuster
Michael E Farkouh
Tunneled left anterior descending artery in a child with hypertrophic cardiomyopathy [0.03%]
肥厚型心肌病患儿左前降支走行异常的病例报告
Iacopo Olivotto,Franco Cecchi,Roberta Bini et al.
Iacopo Olivotto et al.
Background: A 10-year-old boy presented with a history of severe angina on exertion. A two-dimensional echocardiogram showed mild asymmetric left ventricular (LV) hypertrophy localized to the interventricular septum, cons...
Cardiac amyloidosis, a monoclonal gammopathy and a potentially misleading mutation [0.03%]
心脏淀粉样变性、单克隆丙球蛋白血症和可能具有误导性的突变
Ashutosh D Wechalekar,Mark Offer,Julian D Gillmore et al.
Ashutosh D Wechalekar et al.
Background: A 46-year-old Afro-Caribbean man presented with progressive dyspnea and recurrent syncope. Clinical examination revealed evidence of biventricular failure. ...
Triglycerides and cardiovascular events in ACS: the need for combined lipid-altering therapies [0.03%]
急性冠脉综合征患者甘油三酯与心血管事件的关系及联合调脂治疗的必要性
Robert S Rosenson,Bertram Pitt
Robert S Rosenson
Observational study of mortality risk stratification by ischemic presentation in patients with acute type A aortic dissection: the Penn classification [0.03%]
急性A型主动脉夹层患者依据缺血表现的死亡风险分层观察研究：宾大分类体系
John G T Augoustides,Arnar Geirsson,Wilson Y Szeto et al.
John G T Augoustides et al.
Background: Acute type A aortic dissection is a surgical emergency, with an operative mortality as high as 25%. Ischemia is a known predictor of mortality. We tested the efficacy of a classification system--the Penn class...