Elizabeth A Platz
Elizabeth A Platz
This commentary discusses the findings of Agalliu and colleagues, who performed a population-based, case-control study on the association between statin drugs and prostate cancer risk. Consistent with recent studies, statins were not associ...
What is the role of digital rectal examination in men undergoing serial screening of serum PSA levels? [0.03%]
连续进行血清PSA检测的男性中直肠指检的作用是什么？
Stacy Loeb,William J Catalona
Stacy Loeb
This Practice Point commentary discusses the study by Gosselaar et al. that reports the performance characteristics of digital rectal examination (DRE) in men from the Rotterdam cohort of the European Randomized Study of Screening for Prost...
Subtypes of alpha1-adrenoceptors in BPH: future prospects for personalized medicine [0.03%]
前列腺增生α1肾上腺素受体亚型的分类及其在个体化医疗中的前景展望
Yoshiyuki Kojima,Shoichi Sasaki,Yutaro Hayashi et al.
Yoshiyuki Kojima et al.
The alpha(1)-adrenoceptors (alpha(1)-ARs) are involved in regulation of prostatic smooth muscle tone, and are a critical mediator of lower urinary tract symptoms and pathophysiology in benign prostatic hyperplasia (BPH). As a result, alpha(...
Chris F Heyns,Adam E Groeneveld,Nelson B Sigarroa
Chris F Heyns
In recent years the nature of HIV infection has been dramatically transformed from an invariably fatal disease to a chronic disorder with a relatively benign course. Disease progression from HIV to AIDS and HIV-related mortality can be redu...
Photodynamic therapy for prostate cancer--a review of current status and future promise [0.03%]
光动力疗法治疗前列腺癌现状及前景综述
Caroline M Moore,Doug Pendse,Mark Emberton
Caroline M Moore
Debate is ongoing about the treatment of organ-confined prostate cancer, particularly in men who have low-risk disease detected by PSA screening. A balance is needed between the harms and benefits of treatment. New techniques are being deve...
Single-port surgery for donor nephrectomy: a new era in laparoscopic surgery? [0.03%]
供者肾脏单端口手术：腹腔镜手术的新纪元？
Mahesh Desai
Mahesh Desai
High complication rates challenge the implementation of male circumcision for HIV prevention in Africa [0.03%]
高并发症率对非洲地区实施割包皮预防艾滋病的推广工作构成挑战
Howard H Kim,Marc Goldstein
Howard H Kim
This commentary discusses the study by Bailey and colleagues, who aimed to assess the safety of male circumcision practices in both clinical and traditional settings in Bungoma, Kenya. The study evaluated 1,007 males who underwent circumcis...
Should an antimuscarinic agent be used for persistent LUTS after treatment with an alpha(1)-blocker? [0.03%]
α受体阻滞剂治疗后仍存在持续性下尿路症状时需使用抗胆碱药物吗？
Yukio Homma
Yukio Homma
This Practice Point discusses the study by MacDiarmid and colleagues, which is the latest to support a beneficial effect of adding antimuscarinic agents to alpha(1)-blockers in men with persistent lower urinary tract symptoms. Such studies ...
Peter C Albertsen
Peter C Albertsen
The report by Bill-Axelson et al. challenges current paradigms for diagnosis and treatment of prostate cancer. Contemporary dogma based on 8-year outcomes holds that early diagnosis and treatment improve survival, but after 12 years' follow...
Does on-demand vardenafil improve erectile function recovery after radical prostatectomy? [0.03%]
按需服用瓦他林能否改善根治性前列腺切除术后的勃起功能恢复？
John P Mulhall
John P Mulhall
The randomized, placebo-controlled trial reported by Montorsi and colleagues attempted to determine if nightly vardenafil was more effective than on-demand drug in restoring erectile function after radical prostatectomy. No significant diff...