What is the standard chemotherapy for colorectal cancer patients with resectable liver metastases? [0.03%]
可切除肝转移灶的结直肠癌患者的标准化疗是什么？
Bert H O&#x;Neil,Richard M Goldberg
Bert H O&#x;Neil
Philip Savage,Justin Stebbing,Mark Bower et al.
Philip Savage et al.
Despite frequent responses to chemotherapy, curative treatment remains elusive for the majority of patients with metastatic solid tumors. By contrast, in testicular cancer, gestational choriocarcinoma, Hodgkin disease and high-grade lymphom...
Lisa Hutchinson,Vincent T DeVita Jr
Lisa Hutchinson
Re: Therapy Insight: anthracyclines and trastuzumab--the optimal management of cardiotoxic side effects [0.03%]
关于治疗观点：蒽环类药物和赫赛汀——心血管毒副作用的合理管理
Nicolas Magné,Cyrus Chargari
Nicolas Magné
Prophylactic and therapeutic anticoagulation for thrombosis: major issues in oncology [0.03%]
肿瘤学中抗凝预防和治疗血栓形成的重大问题
Marc Carrier,Agnes Y Y Lee
Marc Carrier
Venous thromboembolism (VTE) is a major cause of morbidity and mortality in patients with cancer. Primary prevention with pharmacologic agents (or mechanical methods, if anticoagulants are contraindicated) is recommended in all cancer patie...
A comparison of XELOX with FOLFOX-4 as first-line treatment for metastatic colorectal cancer [0.03%]
比较卡培他滨+奥沙利铂(XELOX)与氟尿嘧啶、亚叶酸钙和伊立替康(FOLFOX-4)作为转移性结直肠癌一线治疗的疗效：一项随机试验
Axel Grothey
Axel Grothey
Oral capecitabine has been shown to be a convenient and well tolerated alternative to intravenous 5-fluorouracil (5-FU) in the treatment of colorectal cancer. The question of whether capecitabine is an adequate and equally effective substit...
Comparative Study
Nature clinical practice. Oncology. 2009 Jan;6(1):10-1. DOI:10.1038/ncponc1261 2009
Is abiraterone acetate well tolerated and effective in the treatment of castration-resistant prostate cancer? [0.03%]
阿比特龙治疗难治性前列腺癌的疗效及耐受性如何？
Emmanuel S Antonarakis,Mario A Eisenberger
Emmanuel S Antonarakis
This Practice Point commentary discusses the findings of the first phase I trial to evaluate abiraterone acetate (an inhibitor of the androgen-regulating enzyme CYP17) in the treatment of castration-resistant prostate cancer. This open-labe...
Rachel Midgley,David J Kerr
Rachel Midgley
In the past 5-10 years there has been a growing trend for substituting conventional 5-fluorouracil with the oral prodrug of 5-fluorouracil, capecitabine, in chemotherapy regimens. This regimen change is based on evidence of the efficacy equ...
Angiosarcoma of the breast following surgery and radiotherapy for breast cancer [0.03%]
乳腺癌手术和放疗后的乳腺血管肉瘤
Rachel Abbott,Carlo Palmieri
Rachel Abbott
Breast angiosarcoma following surgery and radiotherapy for breast cancer is a rare but important clinical entity. This article reviews all published cases and includes data on incidence, etiology, presentation, diagnosis, management and pro...
New challenges and opportunities in the management of brain metastases in patients with ErbB2-positive metastatic breast cancer [0.03%]
HER2阳性转移性乳腺癌患者脑转移的管理面临的新挑战和机遇
Michelle E Melisko,Michael Glantz,Hope S Rugo
Michelle E Melisko
The introduction of trastuzumab for the treatment of tumors that overexpress ErbB2 (also known as HER2) has contributed significantly to recent improvements in systemic therapy for advanced breast cancer. The advances in systemic therapy ha...