Association of polymorphism -308G/A in tumor necrosis factor-alpha gene (TNF-α) and TNF-α serum levels in patients with relapsing-remitting multiple sclerosis [0.03%]
肿瘤坏死因子α基因(TNF-α)-308G/A多态性与复发缓解型多发性硬化患者血清中TNF-α水平关系的研究
Antonia A Grigorova,Anastasiya G Trenova,Spaska A Stanilova
Antonia A Grigorova
TNF-α is an important cytokine of the inflammatory response involved in the pathogenesis of relapsing-remitting multiple sclerosis (RRMS). The aim of this study is to explore the association between the promoter polymorphism -308G/A in the...
Exome sequencing of a Pakistani family with spastic paraplegia identified an 18 bp deletion in the cytochrome B5 domain of FA2H [0.03%]
巴基斯坦一家系进行外显子组测序发现FA2H基因细胞色素B5结构域的18bp缺失变异与遗传性双下肢痉挛性截瘫相关
Safdar Abbas,Beatrice Brugger,Muhammad Zubair et al.
Safdar Abbas et al.
Hereditary spastic paraplegias (HSPs) are a diverse class of neurodegenerative disorders that mainly affect the corticospinal tract of the body and result in various clinical conditions such as lower limb spasticity and muscle weakness in t...
A novel idea for establishing Parkinson's disease mouse model by intranasal administration of paraquat [0.03%]
一种全新的鼻内给药美多巴建立帕金森病小鼠模型的方法
Yi-Bing Chen,Yan-Qiu Wang,Jia-Rong Wu et al.
Yi-Bing Chen et al.
Background: In this study, we sought to provide an idea for establishing a novel mouse model for Parkinson's disease (PD) through intranasal administration of paraquat instead of the conventional method of intraperitoneal injection. Intrana...
Use of BRASS in sedated critically-ill patients as a predictable mortality factor: BRASS-ICU [0.03%]
BRASS预测重症监护室镇静患者死亡率的临床应用价值研究
Vincent Legros,Bruno Mourvillier,Thierry Floch et al.
Vincent Legros et al.
Objectives: To demonstrate that a BRASS score≥ 3 at admission of intubated, ventilated and sedated patients is predictive of mortalityMethods: we have realized an Observational prospective multicenter study.All Major patients without neuro...
Observational Study
Neurological research. 2021 Apr;43(4):283-290. DOI:10.1080/01616412.2020.1849901 2021
LINC00943 knockdown attenuates MPP+-induced neuronal damage via miR-15b-5p/RAB3IP axis in SK-N-SH cells [0.03%]
LINC00943通过miR-15b-5p/RAB3IP轴减轻MPP?在SH?-SY5Y神经元细胞中的诱导损伤
Chunming Meng,Jing Gao,Qingyuan Ma et al.
Chunming Meng et al.
Objectives: Parkinson's disease (PD) is a neurodegenerative problem correlated with neuronal damage. Long noncoding RNAs (lncRNAs) are implicated in neuronal damage in PD development. This research aims to analyze the fun...
Application of functional imaging, neuronavigation, and intraoperative MR imaging in the surgical treatment of brain cavernomas [0.03%]
功能影像、神经导航和术中磁共振在脑海绵状血管瘤手术治疗中的应用
Fabian Winter,Lisa Blair,Michael Buchfelder et al.
Fabian Winter et al.
Objective: The aim of this study was to investigate whether preoperative functional imaging and intraoperative magnetic resonance imaging (iMRI) facilitate surgery and improve outcomes in the surgical treatment of cavernous malformations of...
Efficacy of arterial spin labeling magnetic resonance imaging with multiple post-labeling delays to predict postoperative cerebral hyperperfusion in carotid endarterectomy [0.03%]
采用多时相动脉自旋标记技术预测颈内动脉剥脱术后脑高灌注的疗效研究
Hidenori Endo,Miki Fujimura,Atsushi Saito et al.
Hidenori Endo et al.
Introduction: Cerebral hyperperfusion (CHP) syndrome is one of the most deleterious complications after carotid endarterectomy (CEA). Arterial spin labeling (ASL) is a promising non-invasive method to evaluate various hemodynamic parameters...
Can safe and radical resection of all types of parasagittal meningiomas be achievable? -the introduction of a simplified surgical strategy [0.03%]
所有幕旁脑膜瘤均可实现安全且根治的切除吗？——一种简化的手术策略的引入
Nan Zhang,Tao Yang,Farrukh Hameed et al.
Nan Zhang et al.
Background: Surgery of parasagittal meningiomas (PSMs) is still technically challenging, for the balance between radical resection and preservation of venous circulation. In this article, we'd systemically introduce the technical nuances of...
Evaluating the effect of transplanting umbilical cord matrix stem cells on ischemic tolerance in an animal model of stroke [0.03%]
评估移植胎盘华通胶基质干细胞对卒中动物模型缺血耐受的影响
Mahmoud Ramdan,Mohammad Reza Bigdeli,Sepideh Khaksar et al.
Mahmoud Ramdan et al.
Objective: Stroke, a cerebrovascular disease, has been introduced as the second cause of death and physical disability in the world. Recently, cell-based therapy has been considered by the scientific community as a promis...
Subarachnoid hemorrhage in C57BL/6J mice increases motor stereotypies and compulsive-like behaviors [0.03%]
C57BL/6J小鼠蛛网膜下腔出血增加运动 stereotype 和类似强迫症的行为
Danop Nanegrungsunk,Michael E Ragozzino,Hao-Liang Xu et al.
Danop Nanegrungsunk et al.
Objective: Long-term behavioral, mood, and cognitive deficits affect over 30% of patients with subarachnoid hemorrhage (SAH). The aim of the present study was to examine the neurobehavioral outcomes following endovascular...