Editor-in-Chief [0.03%]
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Shukur Wasman Smail,Arash Abdolmaleki,Mudhir Sabir Shekha
Shukur Wasman Smail
Correlation between single-nucleotide polymorphisms at the rs3745453 locus of the miR-23a gene and sudden sensorineural hearing loss in the Han population [0.03%]
miR-23a基因rs3745453位点单核苷酸多态性与汉族人突发性聋的相关性分析
Peng Chen,Rui Da,Yang Wang
Peng Chen
Objectives: This study aimed to explore the correlation between single-nucleotide polymorphisms (SNPs) of miR-23a (rs3745453) and sudden sensorineural hearing loss (SSNHL) in the Chinese Han population. ...
Assessment of microvascularization is a reliable diagnostic criterion for cerebral ischemia in preterm newborns with oxidative-stress-related conditons [0.03%]
微血管评估是早产儿氧化应激相关性脑缺血的可靠诊断指标
Andriy Zakrevskyy,Kyrylo Zakrevskyi
Andriy Zakrevskyy
Objectives: To improve management of neonatal diseases associated with oxidative stress by introducing advanced diagnostic methods integrating clinical, biochemical, and ultrasound parameters. The study focused on early d...
Efficacy and safety of tirofiban combined with intravenous thrombolysis in Acute ischemic stroke: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials and observational studies [0.03%]
替罗非班联合静脉溶栓治疗急性缺血性卒中的疗效和安全性：基于随机对照试验和观察性研究的系统评价和meta分析（GRADE证据推荐级别评估）
Bilal Wazir Khan,Haris Wazir Khan,Muhammad Huzaifa Khattak et al.
Bilal Wazir Khan et al.
Background: Acute ischemic stroke (AIS) is a leading cause of global morbidity and mortality. Tirofiban, a glycoprotein IIb/IIIa inhibitor, may enhance intravenous thrombolysis outcomes. Updated pooled data are needed to ...
Comparative risk of intracerebral haemorrhage between Tenecteplase and alteplase across doses in acute ischaemic stroke: a network meta-analysis of randomized controlled trials [0.03%]
替奈普酶与阿替普酶治疗急性缺血性卒中的不同剂量下比较性出血风险：随机对照试验的网状Meta分析
João Vitor Andrade Fernandes,João Victor de Oliveira Ramos,Maurus Marques de Almeida Holanda
João Vitor Andrade Fernandes
Introduction: Tenecteplase (TNK) is a potential alternative to standard-dose alteplase (ALT) for intravenous thrombolysis in acute ischaemic stroke (AIS), but its safety may vary by dose. ...
Resveratrol pretreatment modulates SUR1-TRPM4 expression induced by oxygen-glucose deprivation/reoxygenation in brain microvascular endothelial cells [0.03%]
白藜芦醇通过调节脑微血管内皮细胞氧糖剥夺再灌注模型中SUR1-TRPM4的表达发挥神经保护作用
Iván Alquisiras Burgos,Arturo Hernández Cruz,Penélope Aguilera
Iván Alquisiras Burgos
Objective: Cerebral edema is a major contributor to mortality in diverse pathologies; regretfully, no effective therapies can reduce the associated damage. In cerebral ischemia, ionic edema formation is mediated by the su...
Peroxidasin promotes malignant progression by enhancing glycolytic metabolism in glioblastoma through the regulation of LDHA [0.03%]
过氧化酶通过调控LDHA促进胶质母细胞瘤糖酵解代谢增强及恶性进展
Chunlong Ding,Yang Xu,Quanquan Guo et al.
Chunlong Ding et al.
Objectives: Aberrant glucose metabolism serves as a hallmark of glioblastoma (GBM). This study aimed to identify biomarkers linked with glycolysis in GBM, thereby providing a theoretical framework for its treatment. ...
MENA-adapted guidelines for acute ischemic stroke management: a regional approach to global evidence [0.03%]
急性缺血性卒中的中东和北非地区诊疗指南：因地制宜的全球证据选择策略
Ossama Yassin Mansour,Mohamad Ezzeldin,May Nour et al.
Ossama Yassin Mansour et al.
Background: Stroke remains a leading cause of mortality and long-term disability in the Middle East and North Africa (MENA) region. The substantial burden of stroke in low- and middle-income countries, where 75% of stroke...
The morphological characteristics and risk of rupture of ruptured and unruptured internal carotid siphon aneurysms: a preliminary study [0.03%]
未破裂和已破裂颈内动脉海绵窦段动脉瘤形态特征及破裂风险的初步研究
Zhong Huang,Xun Tang,Ruikun Liao
Zhong Huang
Objective: To compare morphological features between ruptured and unruptured internal carotid artery siphon aneurysms (ICSA) and identify predictors associated with rupture risk. ...
Mechanistic study of locally transplanted bone marrow mesenchymal stem cells combined with erythropoietin in acute spinal cord injury [0.03%]
骨髓间充质干细胞移植结合促红细胞生成素治疗急性脊髓损伤的机制研究
Liang Chen,Shuai Tan,Jianwei Wang et al.
Liang Chen et al.
Background: Acute spinal cord injury (SCI) results in irreversible neurological deficits. We hypothesized that local transplantation of bone marrow mesenchymal stem cells (BMSCs) combined with erythropoietin (EPO) would i...