Identification of key genes in intracranial aneurysm via WGCNA: insights into immune microenvironment and therapeutic targets [0.03%]
基于WGCNA的颅内动脉瘤关键基因识别及其免疫微环境和治疗靶点研究
Feng Chen,Pingyou He,Wei Xu et al.
Feng Chen et al.
Background: Intracranial aneurysms (IA) are prevalent vascular lesions whose rupture causes subarachnoid hemorrhage with high disability and mortality. Although cell adhesion molecules help maintain vascular integrity, th...
Association between high-sensitivity C-reactive protein and ischemic stroke outcomes under different glucose metabolism statuses: a retrospective cohort study [0.03%]
高敏C-反应蛋白与不同糖代谢状态的缺血性卒中患者临床结局之间的关联：回顾性队列研究
Jinru Feng,Weili Jia,Kaixuan Yang et al.
Jinru Feng et al.
Background: High-sensitivity C-reactive protein (hs-CRP), a marker of systemic inflammation, is associated with clinical outcomes after stroke. This study aimed to explore the relationship between baseline hs-CRP levels a...
Association between serum inflammatory cytokines, substantia nigra structural changes, and brain functional network in Parkinson's disease [0.03%]
帕金森病患者血清炎症细胞因子与中脑黑质结构改变及大脑功能网络的相关性研究
Ye Liu,Biaoshui Ji,Ziyan Li et al.
Ye Liu et al.
Background: Parkinson's disease (PD), a common neurodegenerative disorder, involves neuroinflammation and abnormal brain structure and function in its pathogenesis. However, integrative studies of multidimensional biomark...
Calpain-1, not Calpain-2, has relationship with HMGB1/TLR4/NF-ΚB signalling pathway variables in multiple sclerosis [0.03%]
与多发性硬化有关的不是-calpain-2而是calpain-1与hmgb1/tlr4/nf-кb信号通路变量相关
Firdevs Uluc,Sule Aydin Turkoglu,Bihter Gokce Celik et al.
Firdevs Uluc et al.
Background: Identification of the related signalling pathways is very crucial for demyelinating diseases. Objectives: The aim of this s...
Modified colloid cyst risk score: a new tool for clinical decision-making in patients with colloid cysts [0.03%]
改良式胶质囊肿风险评分在胶质囊肿患者临床决策中的应用
Ehsan Alimohammadi,Guive Sharifi,Majidreza Farroki et al.
Ehsan Alimohammadi et al.
Background: This study develops the Modified Colloid Cyst Risk Score (MCCRS), a novel, evidence-based tool designed to identify patients with colloid cysts at high risk for clinical deterioration and obstructive hydroceph...
Elevated expression of galectin-3 in microglia exacerbated neuron apoptosis via promoting TNF-α release through the TLR4/NF-κB signaling pathway [0.03%]
微胶质细胞中galectin-3的高表达通过促进TLR4/NF-κB信号途径中的TNF-α释放来加剧神经元凋亡
Cui-Jie Yuan,Meng-Yao Wang,Jiang-Bao Xu et al.
Cui-Jie Yuan et al.
Objectives: High blood levels of galectin-3 (Gal-3) predict poor outcomes after intracerebral hemorrhage (ICH). Our previous study also showed that Gal-3 could aggravate ICH-induced brain injury through increasing neuroin...
Characteristics of SAA, the SII and NT-proBNP levels in patients with ACI and their value in evaluating the prognosis of thrombolytic therapy [0.03%]
急性脑梗死患者SAA、SII及NT-proBNP水平特征及其在溶栓治疗预后评估中的价值
Xianshi Yang,Ailan Pang,Wei Liu et al.
Xianshi Yang et al.
Objective: To explore the features of serum amyloid A (SAA), the systemic immune inflammation index (SII), and N-terminal B-type natriuretic peptide (NT-proBNP) among individuals suffering from acute cerebral infarction (...
Investigation of changes in the choice reaction time with levodopa in patients with Parkinson's disease [0.03%]
左旋多巴对帕金森病患者选择反应时间的影响研究
Halil Onder,Nidanur Kocabacak,Numan Bulut et al.
Halil Onder et al.
Objective: To investigate the alterations in the choice reaction time (RT) with levodopa in Parkinson's disease (PD) patients. Via concurrent clinical assessments, we aimed to provide perspectives regarding the clinical s...
The predictive, preventive, and personalized medicine of multiple sclerosis: ferroptosis and circulating proteins [0.03%]
预测性、预防性和个性化的多发性硬化症医学：铁死亡和循环蛋白
Yao Xiong,Daifeng Yang,Shanshan Cai
Yao Xiong
Objective: Based on the principles of Predictive, Preventive, and Personalized Medicine (PPPM), this study aimed to identify ferroptosis-related genes associated with multiple sclerosis (MS) and to explore the underlying ...
Predictors of botulinum toxin type A response in patients with migraine: a meta-analysis [0.03%]
肉毒杆菌毒素A治疗偏头痛效果的预测因素：一项系统评价和meta分析
Shaoqi Wu,Chang Zhou
Shaoqi Wu
Background: Migraine is one of the most common neurological diseases, imposing a heavy burden on society. Botulinum toxin type A (BT-A) has been approved as a safe and effective preventive treatment; however, not all pati...