Melatonin attenuates neurovascular unit dysfunction via AKT/GSK-3β/CREB pathway in hypoxic-ischemic neonatal rats [0.03%]
褪黑素通过Akt/GSK-3β/CREB信号途径减轻缺氧缺血性脑损伤新生大鼠神经血管单元功能障碍
Chenmeng Liu,Miao Yu,Yijing Wang et al.
Chenmeng Liu et al.
Objectives: Previous research has shown that melatonin (Mel) can alleviate hypoxic-ischemic brain damage (HIBD) in newborns. The roles of Mel on neurovascular unit (NVU) after HIBD and the mechanisms were explored in this...
A pilot cohort study of feasibility and safety of early passive upright positioning for neurocritically ill patients [0.03%]
神经重症患者早期被动直立位姿势的可行性与安全性试点队列研究
Geng Jia,Zhenwei Liu,Changchun Yang et al.
Geng Jia et al.
Objectives: To evaluate the feasibility and safety of passive upright positioning (PUP) using a standing bed in neurocritically ill patients. Methods: ...
Association between herpes simplex virus type 2 infection and 1-year risk of ischemic stroke recurrence: a prospective cohort study [0.03%]
人疱疹病毒2型感染与缺血性卒中复发风险的关系：一项基于前瞻性队列研究的荟萃分析
Ling Hu,Ming Wei,Yanfeng Wang et al.
Ling Hu et al.
Objective: To investigate the association between herpes simplex virus type 2 (HSV-2) infection and 12-month recurrence of acute ischemic stroke (AIS). Me...
Spinal astrocytic EAATs mediate endothelin-1-induced breakthrough cancer pain in mice [0.03%]
小鼠脊髓星形胶质细胞中的EAAT介导癌痛爆发的机制研究
Siqing Jiang,Dong Huang,Lihua Huang et al.
Siqing Jiang et al.
Background: Breakthrough cancer pain (BTcP) lacks representative animal models. The roles of spinal excitatory amino acid transporters (EAATs) in BTcP remain unclear. ...
Study on the mechanism of TMZ resistance in brain glioma regulated by copper death [0.03%]
铜死亡介导的胶质瘤TMZ耐药机制研究
Yabo Sun,Abudula Aisha,Yufei Qu et al.
Yabo Sun et al.
Purpose: The objective of this study is to investigate the mechanism of cuproptosis regulation in TMZ resistance in GBM, and provide an important theoretical basis for the rational design of combination therapy to block T...
Metformin attenuates PTZ-Induced seizures and cognitive impairment and is associated with altered NOS/NO signaling: combined in vivo and in silico evidence [0.03%]
二甲双胍通过抑制NOS/NO信号通路改变削弱戊四唑诱导的癫痫发作和认知障碍：体内与体外联合证据
Arzuhan Çetindağ Çiltaş,Bilal Şahin,Levent Hacisüleyman
Arzuhan Çetindağ Çiltaş
Background: Epilepsy remains a major neurological disorder with high rates of drug resistance and cognitive decline. Repurposing neuroprotective drugs offers a promising approach. Metformin, a widely used antidiabetic age...
Perioperative deep venous thrombosis prophylaxis in patients with glioblastoma: a propensity score-matched comparative study [0.03%]
胶质母细胞瘤患者围手术期深静脉血栓预防的倾向性评分匹配研究
Juan Deng,Jia Liu,Yuan Chen et al.
Juan Deng et al.
Background: To investigate the effectiveness and safety of perioperative prophylaxis protocol for deep venous thrombosis (DVT) in patients undergoing surgery for treating glioblastoma. ...
SP1 and ELAVL1 cooperatively regulate ALOX15-mediated ferroptosis in an OGD/R-Induced SK-N-SH cell model of cerebral infarction [0.03%]
SP1和ELAVL1通过调节ALOX15介导的铁死亡在缺血再灌注诱导的SK-N-SH细胞模型中协同作用
Shunli Liang,You Wu,Rongbo Zhang et al.
Shunli Liang et al.
Background: Cerebral infarction (CI) is associated with high incidence and mortality rates. This study aimed to investigate the role and molecular mechanism of arachidonate 15-lipoxygenase (ALOX15) in oxygen-glucose depri...
Genotype characteristics and therapeutic efficacy trends in spontaneous intracerebral hemorrhage patients treated with intra-hematoma rt-PA thrombolysis [0.03%]
自发性脑出血溶血治疗的基因特征及疗效变化趋势分析
Yonggang Jiao,Xiaorong Zhang,Huaqian Wang
Yonggang Jiao
Objective: To investigate the association between thrombin-activatable fibrinolysis inhibitor (TAFI) genetic polymorphisms and therapeutic efficacy in spontaneous intracerebral hemorrhage (ICH) patients treated with intra...
Ultrasound-guided percutaneous epidural electroacupuncture stimulation for chronic spinal cord injury: a case report [0.03%]
超声引导下椎管内经皮电针刺治疗慢性脊髓损伤病例报告
Yang Wang,Hanxiao Yi,Ping Miao et al.
Yang Wang et al.