Real-world outcomes of myasthenia gravis management: a cross-sectional study at a Korean tertiary center [0.03%]
重症肌无力治疗的现实结果：韩国一家三级医疗机构横断面研究
Ye Joon Jung,Ha Young Shin,Hyung Jun Park et al.
Ye Joon Jung et al.
Introduction: The clinical course and treatment response of myasthenia gravis (MG) vary widely, requiring a comprehensive understanding of treatment outcomes. However, real-world data on Korean MG patients remain limited....
Inflammatory-immune crosstalk in aneurysmal subarachnoid hemorrhage: bidirectional Mendelian randomization and causal mediation evidence [0.03%]
动脉瘤性蛛网膜下腔出血中炎症与免疫的相互作用：双向孟德尔随机化和因果中介证据
Xinyang Yan,Liangchao Jiang,Jiachen Wang et al.
Xinyang Yan et al.
Background: The causal interplay between inflammatory mediators and immune cell phenotypes in aneurysmal subarachnoid hemorrhage (aSAH) remains undefined. We investigated whether immune surface antigens influence rupture ...
Intraprocedural cangrelor during mechanical thrombectomy for acute ischemic stroke: a systematic review and single-arm meta-analysis [0.03%]
急性缺血性卒中行机械取栓术时的术中坎格瑞洛：系统评价与单组meta分析
João Vitor Andrade Fernandes,João Victor de Oliveira Ramos,Maurus Marques de Almeida Holanda
João Vitor Andrade Fernandes
Objective: To evaluate the safety and efficacy of intravenous cangrelor administered during mechanical thrombectomy in patients with acute ischemic stroke. ...
Seren Gülşen Gürgen,Beril Dilber,Özgül Balcı et al.
Seren Gülşen Gürgen et al.
Objectives: Hyponatremia is a frequent electrolyte disturbance that increases seizure susceptibility and may aggravate neuronal injury. Brain-derived neurotrophic factor (BDNF) is a neurotrophin critical for hippocampal f...
NLRX1 orchestrates neuronal mitophagy in Alzheimer's Disease: a mechanistic exploration [0.03%]
NLRX1在阿尔茨海默病中调控神经元线粒体自噬的机制研究
Baoying Qiu,Jiajun He,Shu Li et al.
Baoying Qiu et al.
Background: Mitophagy dysfunction in Alzheimer's Disease (AD) accelerates disease progression, highlighting the need for novel therapeutic targets. Although Nucleotide oligomerization domain - like receptor X1 (NLRX1) reg...
Artificial intelligence in cerebral cavernous malformations: a scoping review [0.03%]
人工智能在脑海绵状血管畸形中的应用：系统综述
Alejandro N Santos,Vigneshwar Venkatesh,Seevakan Chidambaram et al.
Alejandro N Santos et al.
Objectives: Artificial Intelligence (AI) and Machine Learning (ML) are increasingly being applied in medical research, including studies on cerebral cavernous malformations (CCM). This scoping review aims to analyze the s...
Surgical evacuation of acute subdural hematomas in patients aged 65 years or older - a bicentric experience [0.03%]
65岁及以上患者急性硬膜下血肿的手术清除经验──来自两家中心的报告
Thomas Eibl,Carlos Moreno Beredjiklian,Adrian Liebert et al.
Thomas Eibl et al.
Objective: The optimal treatment of elderly patients with acute subdural hematomas (aSDH) remains a subject of ongoing debate. This study aimed to analyze the clinical course of patients aged 65 years or older who underwe...
CD3+ T cell depletion paradoxically worsens intracerebral hemorrhage through blood-brain barrier disruption [0.03%]
CD3+T细胞耗竭通过破坏血脑屏障使颅内出血恶化悖论加重
Chunying Zhu,Yingfu Zhang,Tianci Zhang et al.
Chunying Zhu et al.
Aim: This study aims to assess the involvement of CD3+ T cells in the early stage of cerebral hemorrhage and investigate how depleting CD3+ T cells affects brain injury. ...
Federated deep learning model for epilepsy seizure detection using electroencephalogram (EEG) signal [0.03%]
基于脑电图信号的联邦深度学习癫痫发作检测模型
G R Abijith,S Jothi,Chandrasekar A
G R Abijith
Objectives: Epilepsy is a chronic neurological disorder characterized by recurrent seizures due to abnormal brain activity, which affects individuals' health and quality of life. Traditional seizure detection methods face...
Adipose-derived stem cell exosomes promote neurological recovery after subarachnoid hemorrhage via AMPK/mTOR-mediated TFEB activation [0.03%]
脂肪源性干细胞外泌体通过AMPK/mTOR介导的TFEB活化促进蛛网膜下腔出血后的神经功能恢复
Ming Liu,Song Li,Liang Wu et al.
Ming Liu et al.
Background: Subarachnoid hemorrhage (SAH) is a common neurologically devastating disorder, and existing treatment options remain very limited. Increasing evidence has confirmed the neuroprotective effects of exosomes deri...