Examining Mgat5 upregulation's protective effects and underlying mechanisms in spinal cord injury [0.03%]
Mgat5上调对脊髓损伤保护作用及其机制研究
Bofei Wang,Siyu Jia,Cong He et al.
Bofei Wang et al.
Objective: Secondary inflammation severely hinders recovery after spinal cord injury (SCI). This study investigates whether boosting Mgat5-mediated N-glycosylation via a lentiviral vector can reprogram the local immune mi...
Hypothalamic subregional perfusion alterations in migraine: a 3D-PCASL study [0.03%]
三维定点灌注加权成像技术在偏头痛患者下丘脑亚区灌注改变中的研究
Yu Luo,Zhaodong Zeng,Mengqi Liu et al.
Yu Luo et al.
Background: Migraine is a common neurological disorder with hypothalamic involvement, yet cerebral blood flow (CBF) and volume changes in specific hypothalamic subregions remain unclear. This study used three-dimensional ...
Establishment of a scale to predict acute intracranial atherosclerotic vertebrobasilar artery occlusion before endovascular treatment [0.03%]
建立预测血管内治疗前急性颅内动脉粥样硬化性椎基底动脉闭塞的评分量表
Bo Huang,Guangdong Lu,Yuezhou Cao et al.
Bo Huang et al.
Objectives: Pre-endovascular identification of intracranial atherosclerotic stenosis - related large vessel occlusion (ICAS-LVO) is essential for optimizing recanalization strategy. This study aimed to develop a preoperat...
Multicentre AsPiration Large-vessel Evaluation: Canadian registry of RED-78 aspiration catheter (MAPLE-78) [0.03%]
多中心大血管抽吸评估研究:RED-78抽吸导管加拿大注册研究(MAPLE-78)
Federico Carpani,João André Sousa,Jeremy Rempel et al.
Federico Carpani et al.
Background: Large-bore aspiration catheters are increasingly used for endovascular stroke treatment (EVT). The Penumbra RED-78 is a novel large-bore aspiration catheter for which no clinical data have been published to da...
Admission EASIX is associated with delayed cerebral ischemia and functional outcome after subarachnoid hemorrhage: a retrospective cohort study [0.03%]
Admission EASIX与蛛网膜下腔出血后迟发性脑缺血和功能结局的相关性:一项回顾性队列研究
Nesibe Yıldız Akbulut,Ayşenur Önalan,Erdem Gürkaş
Nesibe Yıldız Akbulut
Background: Endothelial dysfunction plays a central role in secondary brain injury after subarachnoid hemorrhage (SAH). The Endothelial Activation and Stress Index (EASIX), derived from routine laboratory parameters, has ...
Evaluating the strength and quality of evidence in American Heart Association/American Stroke Association's guidelines for primary stroke prevention [0.03%]
美国心脏协会/美国卒中协会的一级卒中预防指南的证据评级和质量评价
Ather Iqbal,Nived Jayaraj Ranjini,Syed A Gillani et al.
Ather Iqbal et al.
Background: Stroke prevention depends on evidence-based guidelines. This study assessed the strength of recommendations and quality of evidence in AHA/ASA primary stroke prevention guidelines across four editions (2006, 2...
Diffusion tensor imaging parameters in the presence of optic neuritis in multiple sclerosis [0.03%]
视神经炎患者的多发性硬化症的扩散张量成像参数分析
Murat Baykara,Ayça Simay Ersöz,Buse Gündoğan et al.
Murat Baykara et al.
Objective: This study examined how different diffusion tensor imaging (DTI) acquisition planes affect diffusion tensor indices in multiple sclerosis (MS) patients, stratified by optic neuritis (ON) history. ...
Does early gastrostomy tube placement after stroke improve functional recovery and quality of life? A literature-informed pathway-decomposition analysis [0.03%]
基于文献的路径分解分析:早期置入胃管对卒中后功能恢复和生活质量的影响评估?
Adnan I Qureshi,Gunjanpreet Kaur,Lourdes Carhuapoma et al.
Adnan I Qureshi et al.
Background and purpose: Optimal timing of gastrostomy tube placement after stroke remains uncertain. Early gastrostomy tube placement may improve outcomes indirectly by facilitating earlier rehabilitation. We evaluated wh...
Predictive ability of cardiac biomarkers for early risk stratification and 3-month functional outcomes after reperfusion therapy in acute ischemic stroke [0.03%]
心肌生物标志物对急性缺血性卒中再灌注治疗后早期风险分层和三个月功能预后的预测能力
Isil Kalyoncu Aslan,Leyla Ramazanoglu,Ozan Keske et al.
Isil Kalyoncu Aslan et al.
Objective: This study aimed to determine the prognostic value of baseline serum cardiac biomarkers measured at emergency department admission in patients with acute ischemic stroke undergoing reperfusion therapy. ...
Luteolin reduces sciatic nerve damage and modulates TRPV1 and TRPM2 expression in diabetic rats [0.03%]
黄酮类化合物山柰酚对糖尿病大鼠坐骨神经病变的保护作用及对瞬时受体电位vanilloid 1和melastatin 2通道表达的影响
Kenan Yildizhan,Fikret Altindağ,Mehmet Hafit Bayir et al.
Kenan Yildizhan et al.
Background: Hyperglycemia drives peripheral nerve damage through oxidative stress, inflammation, and apoptosis, yet the role of redox-sensitive ion channels in linking these processes remains poorly understood. ...