AATF alleviates cerebral ischemia-reperfusion injury by suppressing endoplasmic reticulum stress-induced ferroptosis through upregulating the PI3K/Akt pathway [0.03%]
AATF通过上调PI3K/Akt途径抑制内质网应激诱导的铁死亡从而缓解脑缺血再灌注损伤
Bo Lei,Wenzhang Luo,Qinjing Li et al.
Bo Lei et al.
Objective: The study aimed to investigate the role of apoptosis-antagonizing transcription factor (AATF) in regulating endoplasmic reticulum (ER) stress-ferroptosis interaction and its neuroprotective mechanism in cerebra...
Temporal trends and resource utilization of inter-hospital transfers in acute ischemic stroke: a nationwide retrospective cohort study [0.03%]
急性缺血性卒中院际转诊的时空分布及医疗资源利用特征：全国范围回顾性队列研究
Andrea Loggini,Jonatan Hornik,Amber Schwertman et al.
Andrea Loggini et al.
Purpose: This study investigates temporal trends and resource utilization associated with inter-hospital transfers (IHT) among patients with acute ischemic stroke (AIS). ...
Association between the atherogenic index of plasma and stroke among adults in the United States: a cross-sectional study of NHANES 2017-2018 [0.03%]
2017至2018年美国成人血浆致动脉粥样硬化指数与卒中的关联：基于NHANES的横断面研究
Ziyan Liu,Mengyuan Liu,Dan Wei et al.
Ziyan Liu et al.
Background: The atherogenic index of plasma (AIP) is an innovative and comprehensive lipid metric. We intend to examine the possible correlation between the AIP index and stroke in American adults. ...
Normobaric hyperoxia as an adjuvant to endovascular treatment in acute ischemic stroke: a systematic review and meta-analysis [0.03%]
normobaric吸氧作为急性缺血性卒中介入治疗的辅助治疗：系统评价和meta分析
Tian Wang,Xiaohan Zhang,Pingkai Wang et al.
Tian Wang et al.
Background: Normobaric hyperoxia (NBO) has emerged as a potential adjuvant therapy for enhancing cerebral oxygenation and neuroprotection in patients with acute ischemic stroke (AIS). The combination of endovascular treat...
Predictors of futile recanalization following mechanical thrombectomy in acute ischemic stroke: a single-center retrospective cohort study [0.03%]
急性缺血性卒中机械取栓术后无复流的预测因素：单中心回顾性队列研究
Wu Yuexin,Xinhui Li,Wenjian Su et al.
Wu Yuexin et al.
Background: Despite successful recanalization rates exceeding 85% with mechanical thrombectomy, approximately half of acute ischemic stroke patients with large vessel occlusion experience futile recanalization-vessel reop...
METTL3 improves spinal cord injury-associated locomotor function via SIRT1 m6A modification and regulation of neuronal ferroptosis [0.03%]
METTL3通过SIRT1的m6A修饰和对神经元铁死亡的调节改善脊髓损伤相关的运动功能
Ying Chen,Kaibin Zeng,Gongzhou Chen et al.
Ying Chen et al.
Objective: Inhibition of neuronal ferroptosis is considered crucial for the recovery of locomotor function following spinal cord injury (SCI). We explored the mechanism of methyltransferase-like 3 (METTL3) mediating sirtu...
HSP47 inhibitor Col003 may attenuates neurological impairment in chronic ischemic stroke rats by inhibiting LCN2 [0.03%]
热休克蛋白47抑制剂Col003可通过抑制LCN2缓解慢性卒中大鼠神经功能缺损
Kejian Zhou,Yuliang Xie,Xiaoyun Xie et al.
Kejian Zhou et al.
Objectives: Ischemic stroke often causes severe neurological impairments. Our previous studies showed that Col003, a heat shock protein (HSP47) inhibitor, has neuroprotective effects in acute ischemic stroke, but its role...
Elevated auditory radiation integrity in migraine: evidence from diffusion tensor imaging [0.03%]
偏头痛患者的听觉放射纤维结构完整性升高——弥散张量成像证据
Eva Kiparizoska,Toshikazu Ikuta
Eva Kiparizoska
Background: Auditory symptoms are a common feature in migraines, yet the underlying neural basis is poorly understood. Prior studies have identified thalamic alterations in patients with migraines, particularly in the med...
Causal relationships between micronutrients and intracerebral hemorrhage: univariable and multivariable Mendelian randomization [0.03%]
微量营养素与脑内出血之间的因果关系：单变量和多变量孟德尔随机化
Xiang Niu,Ziyu Zhao,Xiaoxi Wang et al.
Xiang Niu et al.
Background: Intracranial hemorrhage (ICH) prevalence is increasing, yet its genetic risk factors and micronutrient associations remain unclear. Methods: ...
The protective role of miR-672-3p inhibition against ketamine-induced neurological impairment [0.03%]
miR-672-3p抑制对氯胺酮所致神经功能损伤的保护作用
Jianghong Liu,Ruina Guo,Xizhong Ma et al.
Jianghong Liu et al.
Objective: Anesthetic drugs have toxic effects on the central nervous system, leading to cognitive dysfunction. This study aimed to explore the potential protective effect of miR-672-3p against ketamine-induced neurologic...