Application of CRISPR detection technology in screening of stroke susceptibility genes [0.03%]
CRISPR检测技术在筛查卒中易感基因中的应用研究进展
Shuxin Zhang,Mingxu Gao,Zhitao Yu et al.
Shuxin Zhang et al.
Background and purpose: Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) detection technique was used to screen stroke susceptibility gene methyltetrahydrofolate reductase (MTHFR), Shandong Province, to ...
LINC00659 regulates HSP90-IKKα interaction to activate NF-κB signaling and promote glioma invasion [0.03%]
长链非编码RNA LINC00659通过调节HSP90-IKKα相互作用激活NF-κB信号通路促进胶质瘤侵袭
Lijuan Du,Heping Dong,Sunmei Cai et al.
Lijuan Du et al.
Background: Invasiveness of tumor cells constitutes a major obstacle in glioma treatment. While LINC00659 has been implicated in cancer progression, its specific role and underlying mechanisms in glioma remain unclear. ...
BCL11A-triggered IFI6 inhibition reduces glioma cell resistance to temozolomide by promoting ferroptosis [0.03%]
BCL11A诱导的IFI6抑制通过促进铁死亡减少胶质瘤细胞对替莫唑胺的耐药性
Hua Xu,Jun Lu,Lei Wu et al.
Hua Xu et al.
Background: Gliomas, the most common primary brain tumors, are difficult to cure because they often resist chemotherapy. This study explores the mechanisms that might regulate their resistance to the drug temozolomide (TM...
Engineering brain organoids and organ-on-chip systems for modeling neurodevelopmental and neurodegenerative pathophysiology [0.03%]
工程化脑类器官和芯片上大脑系统以模拟神经发育及神经变性疾病病理生理学
Soupayan Banerjee,Pranathi Mirale Chandu,Meghna Sarkar et al.
Soupayan Banerjee et al.
Objectives: Neurodevelopmental and neurodegenerative disorders arise from complex disruptions in brain structure and function, many originating during early development. However, conventional in vitro and animal models of...
KLF2-mediated activation of Nrf2-HO-1 pathway modulates microglia/macrophage polarization post-ischemic stroke [0.03%]
缺血性脑卒中后KLF2介导的Nrf2-HO-1通路活化调节小胶质细胞/巨噬细胞极化的作用机制研究
Gui-Yuan Huang,Hong-Miao Tao,Yuan-Yuan Wu
Gui-Yuan Huang
Background: Shifting the microglia/macrophages from the pro-inflammatory M1 to the anti-inflammatory M2 phenotype shows promise in developing therapeutic strategies after ischemic stroke (IS). The study is aimed to invest...
MiR-92a-3p regulates microglial autophagy and inflammation after intracerebral hemorrhage via ATG14 [0.03%]
microRNA-92a-3p通过ATG14调节颅内出血后的小胶质细胞自噬和炎症反应
Lin Yao,Qian He,Shengyun Hao et al.
Lin Yao et al.
Background: Intracerebral hemorrhage (ICH) is a prevalent cerebrovascular event that triggers secondary brain injury in which microglial activation is central. This study explored how miR-92a-3p governs autophagy and infl...
Correction [0.03%]
改正通知书
Published Erratum
Neurological research. 2025 Dec 3:i. DOI:10.1080/01616412.2025.2594954 2025
Outcomes of mechanical thrombectomy after recent cardiovascular procedures: a multicenter descriptive cohort [0.03%]
机械取栓术治疗近期行心血管手术或介入操作患者的结局：多中心描述性队列研究
Sherief Ghozy,Hatem Tolba,Michael Liu et al.
Sherief Ghozy et al.
Background: Large vessel occlusions (LVOs) in ischemic stroke represent a critical challenge, particularly in the peri-procedural setting of cardiovascular procedures (CVPs). Mechanical thrombectomy (MT) is a well-establi...
Melatonin regulates the MST1/Nrf2 pathway to alleviate oxidative stress injury after hypoxic-ischemic brain damage in neonatal rats [0.03%]
褪黑素通过调节MST1/Nrf2信号通路改善新生鼠缺氧缺血后的氧化应激损伤
Yuexia Zhang,Wenliang Gao,Xiaoqing Jing et al.
Yuexia Zhang et al.
Objective: Oxidative stress is a key factor in neonatal hypoxic-ischemic encephalopathy (HIE). Despite the widespread attention on melatonin (Mel) as a potential therapeutic agent, its antioxidative mechanisms in HIE rema...
Development of a pre-discharge model for 1-year post-discharge all-cause mortality after endovascular treatment for aneurysmal subarachnoid haemorrhage using LASSO-Boruta feature selection [0.03%]
使用LASSO-Boruta特征选择开发动脉瘤性蛛网膜下腔出血血管内治疗后1年全因死亡出院前模型
LongXiang Ma,Bin Zhang,Xiangxin Li et al.
LongXiang Ma et al.
Objective: To develop a predischarge model for predicting 1-year post-discharge all-cause mortality in patients with aneurysmal subarachnoid haemorrhage (aSAH) following endovascular treatment (EVT). ...