Identification of KLRC2 as a candidate marker for brain tumor-initiating cells [0.03%]
鉴定KLRC2作为脑肿瘤起始细胞候选标记物
Eriko Ishihara,Satoshi Takahashi,Raita Fukaya et al.
Eriko Ishihara et al.
Objective: Brain tumor-initiating cells are characterized by their features of self-renewal, multi-lineage differentiation, and tumorigenicity. We analyzed the gene expression of brain tumor-initiating cells to identify their novel cellular...
Propentofylline reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatase-1: An experimental study in a rat model of acute incisional pain [0.03%]
丙克米夫嗪降低急性手术疼痛大鼠模型的机械痛阈并诱导MAPK磷酸酶-1的产生：一项实验研究
Yuanyuan Yang,Yisa Shi,Juan Jia et al.
Yuanyuan Yang et al.
Background: Acute postoperative pain can lead to long hospital stays, dysfunction, and even chronic pain. Mitogen-activated protein kinases (MAPKs) are important in pain signaling. The activity of MAPKs are negatively regulated by dual spec...
Prevention and treatment of experimental autoimmune encephalomyelitis induced mice with 1, 25-dihydroxyvitamin D3 [0.03%]
用1, 25-二羟基维生素D3预防和治疗实验性自身免疫性脑脊髓炎诱导的小鼠
Dariush Haghmorad,Esmaeil Yazdanpanah,Maryam Jadid Tavaf et al.
Dariush Haghmorad et al.
Multiple sclerosis (MS) is a complex inflammatory and demyelinating disease of the central nervous system (CNS) frequently starts in young adulthood. Demyelination, inflammatory and axonal damage in the CNS is the pathological hallmark of e...
Relationships between microRNA-20a and microRNA-125b expression and apoptosis and inflammation in experimental spinal cord injury [0.03%]
microRNA-20a和microRNA-125b表达与实验性脊髓损伤后凋亡及炎症的关系研究
Dilek Şaker,Leman Sencar,Derviş Mansuri Yılmaz et al.
Dilek Şaker et al.
Objectives: The aim of the study was to determine the relationships between microRNA-20a and microRNA-125b expression and apoptosis and inflammation in a rat model of spinal cord injury (SCI) using microscopy, immunohistochemistry, and mole...
Relationships between microRNA-20a and microRNA-125b expression and apoptosis and inflammation in experimental spinal cord injury [0.03%]
microRNA-20a和microRNA-125b表达与实验性脊髓损伤后凋亡及炎症反应的关系研究
Dilek Şaker,Leman Sencar,Derviş Mansuri Yılmaz et al.
Dilek Şaker et al.
Objectives: The aim of the study was to determine the relationships between microRNA-20a and microRNA-125b expression and apoptosis and inflammation in a rat model of spinal cord injury (SCI) using microscopy, immunohistochemistry, and mole...
Intraperitoneal cannabidiol attenuates neonatal germinal matrix hemorrhage-induced neuroinflamation and perilesional apoptosis [0.03%]
大麻二酚的腹膜内给药减轻早产儿脑室内出血所致的局部炎症和细胞凋亡
Timóteo Abrantes De Lacerda Almeida,Marcelo Volpon Santos,Luiza Da Silva Lopes et al.
Timóteo Abrantes De Lacerda Almeida et al.
Background. As the survival of preterm infants has increased significantly, germinal matrix hemorrhage (GMH) has become an important public health issue. Nevertheless, treatment strategies for the direct neuronal injury are still scarce. Th...
Inpatient statin use and stroke recurrence in patients with or without diabetes mellitus [0.03%]
糖尿病患者和非糖尿病患者的住院他汀使用与卒中复发的关系
Xing Zhang,Shu-Ya Li,Jing Jing et al.
Xing Zhang et al.
Objectives: Although statin therapy is associated with lower recurrence in patients with acute ischaemic stroke, data-evaluating associations between inpatient statin use and stroke recurrence in diabetic patients after acute stroke onset a...
Ulinastatin attenuates isoflurane-induced cognitive dysfunction in aged rats by inhibiting neuroinflammation and β-amyloid peptide expression in the brain [0.03%]
乌司他丁通过抑制神经炎症和脑内β淀粉样蛋白表达防治异氟醚致老年大鼠认知障碍的研究
Mingyan Guo,Xiaoqiu Zhu,Hui Xu et al.
Mingyan Guo et al.
Objective: Postoperative neurocognitive disease (PNCD) in the aged is a major clinical problem with unclear mechanisms. This study was designed to explore the mechanisms for ulinastatin (UTI) to attenuate isoflurane-induced cognitive declin...
AAV-mediated siRNA against TRPV1 reduces nociception in a rat model of bone cancer pain [0.03%]
AAV介导的TRPV1siRNA抑制骨癌痛大鼠PVC和足趾回缩痛阈实验式研究
Shuangli Zhang,Jun Zhao,Qinggang Meng
Shuangli Zhang
Objective: Bone cancer pain is characterized by moderate to severe ongoing pain that commonly requires the use of opiates. Transient receptor potential vanilloid subfamily member 1 (TRPV1), a new target of the analgesics, activated by heat,...
Athina Andravizou,Artemios Artemiadis,Christos Bakirtzis et al.
Athina Andravizou et al.
Objectives: In this study, we aimed to explore the extent and clinical relevance of brain volume dynamics in relapsing remitting multiple sclerosis (RRMS). Methods: Sixty-three patients with RRMS with a disease duration of about 5 years (36...