Long-term consequences of polycystic ovary syndrome: results of a 31 year follow-up study [0.03%]
多囊卵巢综合征的长期后果：31年的随访研究结果
Sarah Wild,Tracey Pierpoint,Howard Jacobs et al.
Sarah Wild et al.
A cohort of 786 women who received a diagnosis of polycystic ovary syndrome (PCOS) in the United Kingdom before 1979 was traced to investigate the long-term consequences of the syndrome. Data were obtained from death certificates for 70 wom...
Katherine F. Michelmore
Katherine F. Michelmore
Polycystic ovaries and the associated syndrome are recognized as the most common cause of endocrine disturbances in adult women, but much less research has been performed to examine how polycystic ovary syndrome (PCOS) presents in girls and...
Gerard S. Conway
Gerard S. Conway
Over the past 20 years, it has been established that hyperinsulinaemia is a fundamental disturbance in many women with polycystic ovary syndrome (PCOS). A subgroup of women with this syndrome have 'metabolic PCOS' which can be considered to...
Gillian M. Lockwood
Gillian M. Lockwood
Polycystic ovary syndrome (PCOS) is a common heterogeneous disorder which, in its severest manifestations, is associated with anovulation, hyperandrogenism and metabolic imbalance. The biochemical markers for the condition can include a sig...
Helen Mason
Helen Mason
The mechanism of the increase in the number of follicles in polycystic ovaries (PCO) is still not understood, but most data indicate that folliculogenesis is abnormal at all stages. This increase is probably due to prolonged follicle growth...
Pathogenesis of polycystic ovary syndrome: evidence for a genetically determined disorder of ovarian androgen production [0.03%]
多囊卵巢综合征的发病机理：过度产生卵巢雄激素的遗传性疾病的证据
Stephen Franks,Carole Gilling-Smith,Neda Gharani et al.
Stephen Franks et al.
Polycystic ovary syndrome (PCOS) is the commonest endocrine disorder in women of reproductive age. It is the major cause of anovulatory infertility and of hirsutism but its aetiology remains uncertain. The most consistent biochemical abnorm...
Didier Dewailly
Didier Dewailly
This article aims to answer two questions in defining polycystic ovary syndrome (PCOS): what is PCOS and how should the syndrome be recognized in clinical practice? Whether PCOS is a primary or a secondary ovarian disease remains controvers...
Roy Taylor,Philippa J. Marsden
Roy Taylor
This review sets in context significant recent advances in the understanding of the pathophysiology of polycystic ovary syndrome (PCOS). The occurrence of variable insulin sensitivity in individuals is discussed. Information is presented to...
Obstetric outcome and follow-up of children born after in vitro fertilization (IVF) [0.03%]
体外受精(IVF)出生的后代的围生期结局及随访研究
Ulla-Britt Wennerholm,Christina Bergh
Ulla-Britt Wennerholm
In vitro fertilization (IVF) is a well established and effective method for the treatment of infertility, but there is concern about the health of children born as a result of this procedure. The introduction of new technologies, such as in...
Molecular approaches to the study of gene expression during human preimplantation development [0.03%]
人早期胚胎发育的基因表达研究中的分子方法学进展
Joanna Hurley,John Huntriss,James Adjaye
Joanna Hurley
Understanding of gene expression during the early stages of human development has increased markedly in the last 2 years, as refined and highly sensitive procedures have been developed enabling construction of cDNA libraries from single pre...