Alternations of phospholipid profile in placenta of streptozotocin-induced diabetic rat [0.03%]
链佐星诱导的糖尿病大鼠胎盘磷脂谱的改变
Mina Hasegawa,Katsuhiro Tanaka,Masayuki Komori et al.
Mina Hasegawa et al.
Phospholipids have important roles in many biological processes, but their role in fetal malformation in pregnancy in diabetes is unclear. Metabolic fingerprinting of placental phospholipids in pregnant streptozotocin-induced type 1 diabeti...
Makiko Yamada,Diana Wolfe,Guang Han et al.
Makiko Yamada et al.
Intrauterine growth-restricted (IUGR) newborns have increased risk of adult metabolic syndrome, including fatty liver. However, it is unclear whether the fatty liver development is "programmed" or secondary to the accompanying obesity. In t...
Sexual dimorphism of sulcal length asymmetry in the cerebrum of adult cynomolgus monkeys (Macaca fascicularis) [0.03%]
成人猕猴大脑沟长度侧化的性二态性研究（灵长类动物实验）
Noritaka Imai,Kazuhiko Sawada,Katsuhiro Fukunishi et al.
Noritaka Imai et al.
The present study aimed to quantitatively clarify the gross anatomical asymmetry and sexual dimorphism of the cerebral hemispheres of cynomolgus monkeys. While the fronto-occipital length of the right and left cerebral hemispheres was not d...
Gastroschisis with extracorporeal liver and stomach associated with sacrococcygeal teratoma and limb abnormalities [0.03%]
伴有骶尾部畸胎瘤和肢体畸形的腹裂并肝、胃离体畸形
Sharmila P Bhanu,Devi K Sankar
Sharmila P Bhanu
Gastroschisis is the herniation of abdominal viscera through a paramedian abdominal wall fusion defect without involvement of the umbilical cord. Evisceration usually contains intestinal loops and has no surrounding membrane. Rarely, hernia...
Differences in spontaneous fetal abnormalities among three outbred stocks of Wistar Hannover rats in Japan [0.03%]
日本三种Wistar Hannover系封闭群大鼠自发性胎儿畸形的差异
Tetsuya Takeuchi,Hirokazu Okuda,Yoko Kasahara et al.
Tetsuya Takeuchi et al.
Wistar Hannover rats, which are maintained by three animal breeders in Japan, were examined to obtain basic data on reproductive and developmental parameters. Untreated pregnant females were terminated on gestational day 20, and the fetuses...
Morphological and morphometric study on sphenoid and basioccipital ossification in normal human fetuses [0.03%]
正常人胎颅底蝶骨和枕骨基底部骨化中心发生规律的形态学及形态计量学研究
Qinghua Zhang,Hui Wang,Jun Udagawa et al.
Qinghua Zhang et al.
Congenital anomalies of the brain frequently correspond to cranial base anomalies, and a detailed description of morphology and individual variations in the developing cranial base is of clinical importance for diagnosing anomalies. Develop...
Association of drug treatments in pregnant women with the risk of external ear congenital abnormalities in their offspring: a population-based case-control study [0.03%]
基于人口的病例对照研究发现用药与后代外耳先天畸形风险之间的关联
László Paput,Ferenc Bánhidy,Andrew E Czeizel
László Paput
The objective of this study was to evaluate the possible association of drug treatments in pregnant women with a higher risk of congenital abnormalities of the external ear, particularly microtia/anotia, in their children. The frequency of ...
Seeking gene candidates responsible for developmental origins of health and disease [0.03%]
寻找与健康和疾病的发育起源有关的基因候选者
Tetsuo Ogawa,Randeep Rakwal,Junko Shibato et al.
Tetsuo Ogawa et al.
Human epidemiological evidence has led scientists to theorize that undernutrition during gestation is an important early origin of adult diseases. Animal models have successfully demonstrated that maternal diet could contribute to some adul...
Epithelial Bmp (Bone morphogenetic protein) signaling for bulbourethral gland development: a mouse model for congenital cystic dilation [0.03%]
上皮骨形态生成蛋白信号与尿道球腺发育的关系：先天性囊肿样扩张的小鼠模型
Akiko Omori,Masayo Harada,Sho Ohta et al.
Akiko Omori et al.
The bulbourethral gland (BUG) is a male-specific organ, which secretes part of the semen fluid. As the BUG is located in the deep pelvic floor, its developmental process is still unclear. Bone morphogenetic protein (Bmp) signaling plays piv...
Hypothyroidism caused by phenobarbital affects patterns of estrous cyclicity in rats [0.03%]
苯巴比妥所致的原发性甲状腺功能减退影响大鼠发情周期模式
Yumei Li,Toshihiko Kumazawa,Tsukasa Ishiguro et al.
Yumei Li et al.
We found that repeated treatment with phenobarbital (PB), a thyroid modulator, resulted in a persistent estrous stage in the present study. Although the effects of PB in blocking the surge release of luteinizing hormone (LH), inducing anovu...