Hideto Imura,Ichinnorov Chimedtseren,Hiroo Furukawa et al.
Hideto Imura et al.
Case Reports
Congenital anomalies. 2022 May;62(3):134-135. DOI:10.1111/cga.12459 2022
Application of geometric morphometrics for facial congenital anomaly studies [0.03%]
几何形态计量学在面部先天性畸形研究中的应用
Motoki Katsube,Shigehito Yamada,Natsuko Utsunomiya et al.
Motoki Katsube et al.
The face is a small complex three-dimensional (3D) structure composed of various bones and essential organs. Congenital anomalies of those organs represent various deformities; therefore, their quantification has been challenging. Linear me...
Comparative study on detectability of learning and memory disorder between two water maze tests commonly used in juvenile rat toxicity studies using isoflurane inhaled rat model [0.03%]
异氟醚吸入大鼠模型用于幼年期毒理学研究的两种水迷宫学习记忆功能障碍检测敏感性比较研究
Hiroshi Mineshima,Hiroki Kimoto,Masaya Hitomi et al.
Hiroshi Mineshima et al.
Evaluation of learning and memory is crucial in juvenile animal toxicity studies (JAS) during the development of CNS active drugs, but there are no currently recommended test methods. We compared the ability of the Morris water maze (MWM) a...
Yuko Yamaguchi,Takahiro Yamada,Mikako Goto et al.
Yuko Yamaguchi et al.
To evaluate the safety of triptan use during pregnancy in a Japanese population, we descriptively analyzed the data on pregnancy and fetal outcomes from 128 pregnant women using triptans for migraine treatment at two Japanese facilities tha...
Two new patients with focal dermal hypoplasia: A novel PORCN variant and insights on the diagnostic considerations [0.03%]
一个新的PORCN变异体和诊断方面的见解：两例局灶性真皮发育不全患者
Rasha Moheb Elhossini,Mohamed S Abdel-Hamid,Engy Ashaat et al.
Rasha Moheb Elhossini et al.
Mutations in the PORCN gene cause an X-linked dominant condition; focal dermal hypoplasia (FDH), characterized by atrophic skin, pigmented skin lesions in addition to several ocular and skeletal malformations. FDH is rare with around 275 ca...
Potential role of viral infections in miscarriage and insights into the underlying molecular mechanisms [0.03%]
病毒性感染在流产中的潜在作用及其分子机制研究
Zahra Heydarifard,Sevrin Zadheidar,Jila Yavarian et al.
Zahra Heydarifard et al.
Intrauterine viruses can infect the decidua and placenta and cause adverse effects on the fetus during gestation. This review discusses the contribution of various viral infections to miscarriage and the molecular mechanisms by which viruse...
Cohesinopathy presenting with microtia, facial palsy, and hearing loss caused by STAG1 pathogenic variant [0.03%]
STAG1致病性变异导致的小耳症、面瘫和听力损失引起的连环素病
Michinori Funato,Tomoko Uehara,Yuki Okada et al.
Michinori Funato et al.
Case Reports
Congenital anomalies. 2022 Mar;62(2):82-83. DOI:10.1111/cga.12454 2022
Yuka Adachi,Aina Higuchi,Eri Wakai et al.
Yuka Adachi et al.
Palatogenesis is affected by many factors, including gene polymorphisms and exposure to toxic chemicals during sensitive developmental periods. Cleft palate is one of the most common congenital anomalies, and ongoing efforts to elucidate th...
Identification of a novel mutant allele of LIM homeobox transcription factor 1 alpha (dreher) in mice [0.03%]
小鼠LIM同源框转录因子1α (dreher)新型突变等位基因的鉴定
Jun-Ichi Suto
Jun-Ichi Suto
A male mouse exhibiting bidirectional circling behavior was identified in a Y-chromosome consomic strain known as DH-Chr YRR . The putative mutation responsible for the circling behavior was inherited in an autosomal recessive manner and wa...