Altered Regulation of Type II 11β-hydroxysteroid Dehydrogenase in the Kidney of Rats with Experimental Hypertension [0.03%]
实验性高血压大鼠肾脏组织中二型11β-羟基类固醇脱氢酶表达和活性的改变
Seong Su Kang,Soo Wan Kim,Jongun Lee
Seong Su Kang
The present study was aimed at investigating the role of type II 11β-hydroxysteroid dehydrogenase (IIβ-HSD II) in the development of hypertension. Two-kidney, one-clip (2K1C), deoxycorticosterone acetate (DOCA)/salt, or N (G)-nitro-L-argi...
Immunolocalization of Protein Kinase C Isoenzymes α, βI, βII and γ in Adult and Developing Rat Kidney [0.03%]
α，βI，βII和γ蛋白激酶C等位酶在成年及发育大鼠肾脏中的免疫定位研究
Wan-Young Kim,Gye-Sil Lee,Young-Hee Kim et al.
Wan-Young Kim et al.
Protein kinase C (PKC) plays an important role not only in signal transduction mechanisms in various biological processes, but also in the regulation of growth and differentiation during development. We studied the classical PKCα, βI, βI...
Dysregulation of Renal Cyclooxygenase-2 in Rats with Lithium-induced Nephrogenic Diabetes Insipidus [0.03%]
锂诱导的肾性尿崩症大鼠肾脏环氧化酶-2失调
Tae-Hwan Kwon
Tae-Hwan Kwon
This study aimed to examine whether the expression of major prostaglandin E2 (PGE2) synthesis enzyme, cyclooxygenase-2 (COX-2), is changed in the kidneys of the rats with lithium-induced nephrogenic diabetes insipidus (Li-NDI). Sprague-Dawl...
Effects of Increased Uric Acid Intake on the Abundance of Urate-anion exchanger and Organic Anion Transporter Proteins in the Rat Kidney [0.03%]
增加尿酸摄入对大鼠肾脏尿酸盐阴离子交换器和有机阴离子转运蛋白表达的影响
Sua Kim,Chang Hwa Lee,Chong Myung Kang et al.
Sua Kim et al.
Renal handling of uric acid mainly occurs in the proximal tubule, and bidirectional transport of urate may involve apical absorption via the urate-anion exchanger (URAT1) and basolateral uptake via organic anion transporters (OAT1 and OAT3)...
Altered Regulation of type 3 Na(+)/H(+) exchanger, type 1 Na(+)/HCO3 (-) cotransporter, and Na(+),K(+)-ATPase in the Kidney of Rats with Experimental Rhabdomyolysis [0.03%]
实验性横纹肌溶解大鼠肾脏Na/H交换子3型、Na/HCO3同向转运子1型及Na,K-ATP酶调节异常的研究
Seong Kwon Ma,Eun Hui Bae,Jongun Lee et al.
Seong Kwon Ma et al.
Metabolic acidosis was shown to correlate with deterioration of renal function in patients with rhabdomyolysis. The present study was aimed to investigate whether the changes of type 3 Na(+)/H(+) exchanger (NHE3), type 1 Na(+)/HCO3 (-) cotr...
Tai Yeon Koo,Sang-Cheol Bae,Joon Sung Park et al.
Tai Yeon Koo et al.
Cyclophosphamide is frequently used for the treatment of severe lupus nephritis, but is very rarely associated with dilutional hyponatremia. Recently we experienced a case of water intoxication following low-dose intravenous cyclophosphamid...
Kyun Sang Lee,Taek Won Kang,Seong Kwon Ma et al.
Kyun Sang Lee et al.
Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most common disease leading to hyponatremia, and it is characterized by an inappropriately elevated serum ADH level relative to serum osmolality. This syndrome may occu...
Metabolic acidosis in maintenance hemodialysis patients: clinical impact and intervention [0.03%]
维持性血液透析患者的代谢性酸中毒：临床影响和干预措施
Ho-Jung Kim,Sang-Woong Han
Ho-Jung Kim
Metabolic acidosis has been considered as one of the reverse epidemiologic factors for the morbidity and mortality in maintenance hemodialysis patients (MHP). Expectedly, in the recent large scale epidemiologic study (The Dialysis Outcome P...
Kyu Bok Choi
Kyu Bok Choi
Hypokalemia is a common clinical problem. The kidney is responsible for long term potassium homoeostasis, as well as the serum potassium concentration. The main nephron site where K secretion is regulated is the cortical collecting duct, ma...
Regulation of Urea Transporters by Tonicity-responsive Enhancer Binding Protein [0.03%]
渗透压响应增强子结合蛋白调节尿素转运蛋白的功能及机制研究
Ju-Young Jung,H Moo Kwon,Jim Kim
Ju-Young Jung
Urea accumulation in the renal inner medulla plays a key role in the maintenance of maximal urinary concentrating ability. Urea transport in the kidney is mediated by transporter proteins that include renal urea transporter (UT-A) and eryth...