Occupancy of α7 Nicotinic Acetylcholine Receptors in the Brain by Tropisetron: A Positron Emission Tomography Study Using [(11)C]CHIBA-1001 in Healthy Human Subjects [0.03%]
放射性配体[(11)C]CHIBA-1001的正电子发射断层显像(PET)在健康人体内研究五羟色胺受体3拮抗剂托哌酮对α7型烟碱乙酰胆碱受体脑内占据现象的研究
Masatomo Ishikawa,Muneyuki Sakata,Jun Toyohara et al.
Masatomo Ishikawa et al.
Objective: Agonists of α7-nicotinic acetylcholine receptors (nAChRs) have been developed as potential therapeutic drugs for neuropsychiatric diseases such as schizophrenia and Alzheimer's disease. Positron emission tomog...
Association of the Brain-derived Neurotrophic Factor Gene and Clinical Features of Bipolar Disorder in Korea [0.03%]
韩国脑源性神经营养因子基因与双相情感障碍的临床特征之间的关联研究
Hye Ji Min,Hyun-Sang Cho,Se Joo Kim et al.
Hye Ji Min et al.
Objective: Brain-derived neurotrophic factor (BDNF) plays an important role in cell survival, differentiation, and cell death as well as in neural plasticity. Recent studies have suggested that BDNF is involved in the pat...
Lack of Association between Brain-Derived Neurotrophic Factor Gene Val66Met Polymorphisms and Generalized Social Anxiety Disorder in Korean Population [0.03%]
脑源性神经营养因子基因Val66Met多态性与韩国人群广泛性社交焦虑障碍无相关性
Jin-Sung Park,Sewon Lim,Juwon Ha et al.
Jin-Sung Park et al.
Objective: Several lines of evidence suggest that brain-derived neurotrophic factor (BDNF) plays a role in the pathophysiology of anxiety. We analyzed the association of the BDNF gene polymorphism, G196A (val66met), in th...
Yoshio Kaneko,Matcheri Keshavan
Yoshio Kaneko
Cognitive deficits in schizophrenia are pervasive, severe, and largely independent of the positive and negative symptoms of the illness. These deficits are increasingly considered to be core features of schizophrenia with evidence that the ...
Daniel Martins-de-Souza
Daniel Martins-de-Souza
Schizophrenia is likely to be a multifactorial disorder, consequence of alterations in gene and protein expression since the neurodevelopment that together to environmental factors will trigger the establishment of the disease. In the post-...
The impact of personality traits on emotional responses to interpersonal stress [0.03%]
人格特质对人际压力的情绪反应的影响
Hong Jin Joo,Bora Yeon,Kyoung-Uk Lee
Hong Jin Joo
Objective: The aim of the present study was to examine the impact of personality traits on emotional responses to interpersonal stress. Methods: ...
The Diagnostic Stability of DSM-IV Diagnoses: An Examination of Major Depressive Disorder, Bipolar I Disorder, and Schizophrenia in Korean Patients [0.03%]
依据DSM-IV诊断标准考察韩国患者的诊断稳定性——以抑郁症、躁郁症I型和精神分裂症为例
Won Kim,Young Sup Woo,Jeong-Ho Chae et al.
Won Kim et al.
Objective: We examined the stability of diagnoses defined by the Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition (DSM-IV) (major depressive disorder [MDD], bipolar I disorder [BID], and schizophrenia ...
Diffusion tensor imaging findings of white matter changes in first episode schizophrenia: a systematic review [0.03%]
首发精神分裂症白质改变的弥散张量成像研究系统性综述
Carissa Nadia Kuswanto,Irvin Teh,Tih-Shih Lee et al.
Carissa Nadia Kuswanto et al.
Earlier structural magnetic resonance imaging in schizophrenia have noted smaller white matter volumes in diverse brain regions and recent diffusion tensor imaging (DTI) studies have allowed better elucidation of changes in brain white matt...
Factors that influence the prescription of antipsychotics for patients with schizophrenia in china [0.03%]
影响中国精神分裂症患者使用抗精神病药物处方的因素分析
Tian-Mei Si,Liang Shu,Ke-Qing Li et al.
Tian-Mei Si et al.
Objective: To investigate the patterns of antipsychotic use in China and to analyze the factors that influence antipsychotic prescriptions. Methods: ...
Altered neuronal markers following treatment with mood stabilizer and antipsychotic drugs indicate an increased likelihood of neurotransmitter release [0.03%]
情绪稳定剂和抗精神病药物治疗后神经元标记物发生变化表明神经递质释放的可能性增加
Elizabeth Scarr,Brian Dean
Elizabeth Scarr
Objective: Given the ability of mood stabilizers and antipsychotics to promote cell proliferation, we wanted to determine the effects of these drugs on neuronal markers previously reported to be altered in subjects with p...