Effects of chronic mild stress in female bax inhibitor-1-gene knockout mice [0.03%]
巴克斯抑制因子-1基因敲除小鼠慢性轻度应激的影响
Zhi-Yan Sui,Han-Jung Chae,Guang-Biao Huang et al.
Zhi-Yan Sui et al.
Objective: The anti-apoptotic protein Bax inhibitor-1 (BI-1) is a regulator of apoptosis linked to endoplasmic reticulum (ER) stress, and BI-1(-/-) mice exhibit increased sensitivity to tissue damage. The purpose of this ...
Clinical predictors of drug response in patients with obsessive-compulsive disorder [0.03%]
预测强迫症患者药物疗效的临床指标
Chan-Hyung Kim,Jae-Wook Jeong,Eun Ju Kim et al.
Chan-Hyung Kim et al.
Objective: The aim of this study was to evaluate which clinical variables might influence the antiobsessional responses to proserotonergic drugs in a sample of patients with obsessive-compulsive disorder (OCD). ...
Effects of the antioxidant sulforaphane on hyperlocomotion and prepulse inhibition deficits in mice after phencyclidine administration [0.03%]
抗氧化剂硫代葡萄糖异硫氰酸盐对氯化苯环氮平所致小鼠过度运动和预脉冲感觉抑制缺失的影响
Yumi Shirai,Yuko Fujita,Kenji Hashimoto
Yumi Shirai
Objective: Accumulating evidence suggests that oxidative stress plays a role in the pathophysiology of schizophrenia and that the potent antioxidants may be potential therapeutic drugs for schizophrenia. This study was un...
Are you being rejected or excluded? Insights from neuroimaging studies using different rejection paradigms [0.03%]
被拒绝还是被排斥?不同拒绝范式的神经影像学研究启示
Preethi Premkumar
Preethi Premkumar
Rejection sensitivity is the heightened tendency to perceive or anxiously expect disengagement from others during social interaction. There has been a recent wave of neuroimaging studies of rejection. The aim of the current review was to de...
Antipsychotics prescribing patterns of patients with schizophrenia admitted to korean general hospital psychiatric unit: 2001 to 2008 [0.03%]
2001至2008年韩国综合医院精神科病房的精神分裂症患者的抗精神病药物处方模式
Hye Jin Choi,Seung Ho Jung,Min Hee Kang et al.
Hye Jin Choi et al.
Objective: Although the standard of treatment for schizophrenia is antipsychotic monotherapy, overall psychotropic polypharmacy including antipsychotic polypharmacy is increasingly practiced by clinicians. However, there ...
Use of clozapine for the treatment of schizophrenia: findings of the 2006 research on the china psychotropic prescription studies [0.03%]
氯氮平治疗精神分裂症的用药情况研究——中国处方调查(2006)结果
Tian-Mei Si,Yun-Shu Zhang,Liang Shu et al.
Tian-Mei Si et al.
Objective: Clozapine is one of the most commonly used antipsychotic drugs in China. To date, few studies have investigated the patterns the prescription of clozapine nationwide. The present study examined these patterns i...
Iptakalim Preferentially Decreases Nicotine-induced Hyperlocomotion in Phencyclidine-sensitized Rats: A Potential Dual Action against Nicotine Addiction and Psychosis [0.03%]
伊普他卡林减少尼古丁诱导的苯环己哌啶致敏大鼠的超量运动:针对成瘾和精神病的潜在双重作用
Nick Volf,Gang Hu,Ming Li
Nick Volf
Objective: Iptakalim is a putative ATP-sensitive potassium (K(ATP)) channel opener. It is also a novel nicotinic acetylcholine receptor (nAChR) blocker and can antagonize nicotine-induced increase in dopamine release in t...
Na-Ri Kang,Moon-Doo Kim
Na-Ri Kang
Tardive dyskinesia is characterized by choreiform movements, or rhythmic abnormal involuntary movements of the face, mouth, tongue, trunk, and limbs. It is frequently associated with the use of neuroleptic medications. The choreiform moveme...
Circadian Rhythm Characteristics in Mood Disorders: Comparison among Bipolar I Disorder, Bipolar II Disorder and Recurrent Major Depressive Disorder [0.03%]
情绪障碍的昼夜节律特征:I型双相障碍、II型双相障碍和复发性重大抑郁障碍的比较
Jae Kyung Chung,Kyu Young Lee,Se Hyun Kim et al.
Jae Kyung Chung et al.
Objective: Morningness/eveningness (M/E) is a stable characteristic of individuals. Circadian rhythms are altered in episodes of mood disorder. Mood disorder patients were more evening-type than normal population. In this...
Yong-Sil Kweon,Sunyoung Hwang,Bora Yeon et al.
Yong-Sil Kweon et al.
Objective: Few studies have focused on the characteristic features of drug overdose in children and adolescents who have attempted suicide in Korea. The present study examined the characteristics of drug overdose in child...