Pharmacokinetics and Safety of Duloxetine Enteric-coated Tablets in Chinese Healthy Volunteers: A Randomized, Open-label, Single- and Multiple-dose Study [0.03%]
duloxetine肠溶片在中国健康志愿者中的药代动力学及安全性：一项随机、开放标记的单次和多次给药研究
Huafang Li,Ting Li,Yan Li et al.
Huafang Li et al.
Objective: Duloxetine hydrochloride is a selective serotonin (5-hydroxytryptamine) and norepinephrine reuptake inhibitor. It is approved for effective treatment for major depressive disorder. The pharmacokinetics (PK) of ...
A Longitudinal Study of Relation between Side-effects and Clinical Improvement in Schizophrenia: Is There a Neuro-metabolic Threshold for Second Generation Antipsychotics? [0.03%]
关于副作用与临床疗效关系的纵向研究——第二代抗精神病药物是否存在神经代谢阈值？
Ganesan Venkatasubramanian,Naren P Rao,Rashmi Arasappa et al.
Ganesan Venkatasubramanian et al.
Objective: Classical studies demonstrated Neuroleptic Induced Extrapyramidal Side-effects (NIES; Neuroleptic threshold) to correlate with the efficacy of first generation antipsychotics. Second generation antipsychotics (...
Shoji Tanaka,Takanori Nagase,Takefumi Suzuki et al.
Shoji Tanaka et al.
Objective: The aim of this study was to explore the factor structure of a novel, 10-item rating scale, the Targeted Inventory on Problems in Schizophrenia (TIP-Sz). Determining the factor structure will be useful in the b...
No Association between the Response to Methylphenidate and DRD4 Gene Polymorphism in Korean Attention Deficit Hyperactivity Disorder: A Case Control Study [0.03%]
注意缺陷多动障碍韩国儿童哌甲酯疗效与DRD4基因多态性无相关性：病例对照研究
Hyun Soo Ji,Ki Chung Paik,Woo Sung Park et al.
Hyun Soo Ji et al.
Objective: Recently the relationship between alleles frequency distribution, drug response and the attention deficit hyperactivity disorder (ADHD), has been actively researched. We investigated the association between the...
Hoyoung An,Hyunjoo Sohn,Seockhoon Chung
Hoyoung An
A safe and effective way to control weight in patients with affective disorders is needed, and phentermine is a possible candidate. We performed a PubMed search of articles pertaining to phentermine, sibutramine, and affective disorders. We...
Hyun-Ghang Jeong,Moon-Soo Lee
Hyun-Ghang Jeong
Antipsychotic medications are important for the successful management of schizophrenia. Continuous treatment with medication is superior in relapse prevention and non-adherence to antipsychotic medication is associated with a poor clinical ...
A BDNF Val66Met Polymorphism and Ketamine-induced Rapid Antidepressant Action [0.03%]
BDNF Val66Met多态性与氯胺酮快速抗抑郁作用的关系研究
Kenji Hashimoto
Kenji Hashimoto
The Tolerability of Mirtazapine Augmentation in Schizophrenic Patients Treated with Risperidone: A Preliminary Randomized Placebo-controlled Trial [0.03%]
利培酮治疗的 schizophrenia 患者中米氮平增效疗法的耐受性：一项初步随机双盲安慰剂对照试验
Jieun Lee,Sung Joon Cho,Kang Soo Lee et al.
Jieun Lee et al.
Objective: Some patients with schizophrenia may need mirtazapine augmentation to improve negative and cognitive symptoms. However there have been a few studies about the tolerability of mirtazapine augmentation to antipsy...
Pharmacogenetic Aspects of Antipsychotic Drug-induced Weight Gain - A Critical Review [0.03%]
抗精神病药物致体重增加的药理遗传学方面-一篇评述性文章
Gavin P Reynolds
Gavin P Reynolds
Treatment with several antipsychotic drugs can result in weight gain, which may lead to further morbidity such as type 2 diabetes and cardiovascular disease via the development of metabolic syndrome. These important and problematic metaboli...