A Pilot Study for Discovering Candidate Genes of Chromosome 18q21 in Methamphetamine Abusers: Case-control Association Study [0.03%]
关于甲基苯丙胺滥用者染色体18q21位点候选基因的病例对照关联研究的探索性研究
Byung Dae Lee,Je Min Park,Young Min Lee et al.
Byung Dae Lee et al.
Objective: It was previously suggested that the malic enzyme 2 (ME2) as the candidate gene for psychosis in fine mapping of chromosome 18q21. Chromosome 18q21 is also one of the possible regions that can contribute to add...
Drug Treated Schizophrenia, Schizoaffective and Bipolar Disorder Patients Evaluated by qEEG Absolute Spectral Power and Mean Frequency Analysis [0.03%]
药物治疗的分裂症，分裂情感和双相情感障碍患者的qEEG绝对谱功率和平均频率分析评估
Richard Wix-Ramos,Xiomara Moreno,Eduardo Capote et al.
Richard Wix-Ramos et al.
Objective: Research of electroencephalograph (EEG) power spectrum and mean frequency has shown inconsistent results in patients with schizophrenic, schizoaffective and bipolar disorders during medication when compared to ...
Comparison of Memory Function and MMPI-2 Profile between Post-traumatic Stress Disorder and Adjustment Disorder after a Traffic Accident [0.03%]
交通事故后 PTSD 与适应障碍患者的记忆功能及 MMPI-2 测验结果的比较研究
Sung-Man Bae,Myoung-Ho Hyun,Seung-Hwan Lee
Sung-Man Bae
Objective: Differential diagnosis between post-traumatic stress disorder (PTSD) and adjustment disorder (AD) is rather difficult, but very important to the assignment of appropriate treatment and prognosis. This study inv...
Duloxetine, a Selective Noradrenaline Reuptake Inhibitor, Increased Plasma Levels of 3-Methoxy-4-hydroxyphenylglycol but Not Homovanillic Acid in Patients with Major Depressive Disorder [0.03%]
度洛西汀，一种选择性去甲肾上腺素再摄取抑制剂，增加了抑郁症患者高香草酸而不是3-甲氧基-4-羟基苯甘氨酸的血浆水平
Kiyokazu Atake,Reiji Yoshimura,Hikaru Hori et al.
Kiyokazu Atake et al.
Objective: We investigated the effects of duloxetine on the plasma levels of catecholamine metabolites and serum brain-derived neurotrophic factor (BDNF) in 64 patients with major depressive disorder (MDD). ...
Effects of Brilliant Blue G on Serum Tumor Necrosis Factor-α Levels and Depression-like Behavior in Mice after Lipopolysaccharide Administration [0.03%]
苏丹红G对脂多糖所致小鼠血清肿瘤坏死因子-α水平及抑郁样行为的影响
Min Ma,Qian Ren,Ji-Chun Zhang et al.
Min Ma et al.
Objective: Accumulating evidence suggests that inflammation plays a role in the pathophysiology of major depression. The adenosine triphosphate (ATP)-sensitive P2X7 receptor (P2X7R) plays a crucial role in microglial acti...
Advanced pharmacotherapy evidenced by pathogenesis of autism spectrum disorder [0.03%]
基于自闭症谱系障碍发病机制的药物治疗进展
Yeon Jung Lee,Soo Hyun Oh,Chanmin Park et al.
Yeon Jung Lee et al.
In clinical practice, pharmacological treatment is mostly focused on behavioral symptoms in everyday life. Nevertheless, persistent effort continues to develop medication for causal treatment. Recent changes in diagnostic criteria from Diag...
Neuroimmunological aberrations and cerebral asymmetry abnormalities in schizophrenia: select perspectives on pathogenesis [0.03%]
精神分裂症的神经免疫异常和大脑不对称性异常：对发病机制的一些观点
Ganesan Venkatasubramanian,Monojit Debnath
Ganesan Venkatasubramanian
Within the wide-ranging gamut of factors that comprise gene-environment interactions postulated to underlie schizophrenia, the crosstalk between environmental factors and feto-maternal immune components has been put forth as one of the impo...
Strategies for Early Non-response to Antipsychotic Drugs in the Treatment of Acute-phase Schizophrenia [0.03%]
抗精神病药物早期无效治疗急性期精神分裂症的策略研究
Kotaro Hatta,Hiroto Ito
Kotaro Hatta
As a strategy for antipsychotic treatment of schizophrenia, monotherapy is clearly optimal when both effective and tolerated. When a patient fails to respond to an adequate dose of an antipsychotic, alternatives include switching, administe...
Successful Early Clozapine Trial in the Treatment of First-episode Schizophrenia: A Case Report [0.03%]
氯氮平治疗首发精神分裂症的早期成功尝试：病例报告
Yeon-Jin Kim,Seung-Ho No,Sang-Yeol Lee
Yeon-Jin Kim
Clozapine remains the treatment of choice in refractory schizophrenia despite its various requirement to prescribe, such as mandatory blood monitoring program and various metabolic complication. Currently, clozapine is recommended only afte...
Blonanserin-induced Mood Alteration in Schizophrenia and Schizoaffective Disorder: Two Cases [0.03%]
两例精神分裂症和分裂情感障碍患者使用布南色林后出现情绪变化的病例报告
Aran Min,Daeho Kim
Aran Min
We report two outpatients, one with schizophrenia and one with schizoaffective disorder, who developed manic or hypomanic episodes following the initiation of blonanserin during the course of treatment. Blonanserin is a novel antipsychotic ...