Predictors of Remission in Acute and Continuation Treatment of Depressive Disorders [0.03%]
抑郁症急性期和维持治疗缓解的预测指标
Ha-Yeon Kim,Hee-Joon Lee,Min Jhon et al.
Ha-Yeon Kim et al.
Objective: To identify factors predicting remission of depression during acute (12 weeks) and continuation treatment (12 months) using a 1-year, naturalistic prospective study design. ...
Efficacy of Ulinastatin and Sulforaphane Alone or in Combination in Rat Model of Streptozotocin Diabetes Induced Vascular Dementia [0.03%]
乌拉立坦和硫化萝卜素除单用外联合用药对链脲佐菌素糖尿病大鼠血管性痴呆的作用及机制研究
Poonam Sharma,Prachi Kaushik,Swati Jain et al.
Poonam Sharma et al.
Objective: Vascular Dementia (VaD), is associated with metabolic conditions. Diabetes is a major risk factor for the development of VaD. This study investigates the efficacy of ulinastatin (UTI) and sulforaphane (SUL) in ...
Real-world Evaluation of Tolerability, Safety and Efficacy of Rivastigmine Oral Solution in Patients with Mild to Moderate Alzheimer's Disease Dementia [0.03%]
盐酸利斯的明口服溶液治疗轻至中度阿尔茨海默病痴呆患者耐受性、安全性和有效性的真实世界评价研究
Sun-Wung Hsieh,Jui-Cheng Chen,Nai-Ching Chen et al.
Sun-Wung Hsieh et al.
Objective: The purpose of this study is to investigate the safety, tolerability and efficacy of titrating dose of rivastigmine oral solution in patients with mild to moderate Alzheimer's disease (AD) in Taiwan. ...
White Matter Alterations Associated with Pro-inflammatory Cytokines in Patients with Major Depressive Disorder [0.03%]
抑郁症患者白质改变与促炎症细胞因子有关联
Jaehwa Lim,Hoyoung Sohn,Min-Soo Kwon et al.
Jaehwa Lim et al.
Objective: Regarding the neuroinflammatory theory of major depressive disorder (MDD), little is known about the effect of pro-inflammatory cytokines on white matter (WM) changes in MDD. We aimed to investigate the relatio...
Consideration of Long-Acting Injectable Antipsychotics for Polypharmacy Regimen in the Treatment of Schizophrenia: Put It on the Table or Not? [0.03%]
长效注射抗精神病药物是否应纳入多药治疗方案以治疗精神分裂症？
Chi-Un Pae,Changsu Han,Won-Myong Bahk et al.
Chi-Un Pae et al.
Antipsychotic monotherapy (APM) is considered best-acceptable treatment option regardless of antipsychotic class and formulation types for treating schizophrenia. However, antipsychotic polypharmacy (APP) has been also widely utilized in ro...
Novel Biomarkers of Alzheimer's Disease: Based Upon N-methyl-D-aspartate Receptor Hypoactivation and Oxidative Stress [0.03%]
阿尔茨海默病的新生物标志物：基于N-甲基-D-天冬氨酸受体低功能和氧化应激
Ting-I Chiang,Yi-Hsiang Yu,Chieh-Hsin Lin et al.
Ting-I Chiang et al.
Early detection and prevention of Alzheimer's disease (AD) is important. The current treatment for early AD is acetylcholine esterase inhibitors (AChEIs); however, the efficacy is poor. Besides, AChEI did not show efficacy in mild cognitive...
Challenges in Prescribing Clozapine in the Era of COVID-19: A Review Focused on Immunological Implications [0.03%]
新冠时代氯氮平处方的挑战：免疫影响的综述研究
Seong Hoon Jeong,Yong Sik Kim
Seong Hoon Jeong
The global COVID-19 pandemic has disrupted every aspect of the healthcare system. Apart from the issues surrounding COVID-19 itself, care for existing patients has met many challenges. One such challenge is caring for patients who are on cl...
A New Look on an Old Issue: Comprehensive Review of Neurotransmitter Studies in Cerebrospinal Fluid of Patients with Schizophrenia and Antipsychotic Effect on Monoamine's Metabolism [0.03%]
旧议题 新视角：中枢神经系统精神分裂症患者脑脊液神经递质的全面回顾及抗精神病药物对单胺代谢的影响
Matthieu Gasnier,Pierre Ellul,Marion Plaze et al.
Matthieu Gasnier et al.
Neurotransmitters metabolism has a key role in the physiopathology of schizophrenia as demonstrated by studies measuring monoamine metabolites in patient's cerebrospinal fluid (CSF) since the beginning of the antipsychotic use. This compreh...
In Reply: Trough Melatonin Levels Have No Physiological or Clinical Relevance [0.03%]
关于回信：褪黑激素低谷水平没有生理或临床意义
Chieh-Hsin Lin,Hsien-Yuan Lane
Chieh-Hsin Lin
David J Kennaway
David J Kennaway