Brain Derived Neurotrophic Factor Methylation and Long-term Outcomes after Stroke Interacting with Suicidal Ideation [0.03%]
脑源性神经营养因子甲基化在自杀意念的交互作用下对卒中长期结局的影响
Hee-Ju Kang,Ju-Wan Kim,Joon-Tae Kim et al.
Hee-Ju Kang et al.
Objective: This study aimed to evaluate the unexplored relationship between BDNF methylation, long-term outcomes, and its interaction with suicidal ideation (SI), which is closely associated with both BDNF expression and ...
Epigenome-wide Association Study for Tic Disorders in Children: A Preliminary Study in Korean Population [0.03%]
儿童抽动障碍的表观基因组关联研究:韩国人群初步研究
Young Kyung Ko,Suhyuk Chi,Gyu-Hwi Nam et al.
Young Kyung Ko et al.
Objective: : Tic disorders can affect the quality of life in both childhood and adolescence. Many factors are involved in the etiology of tic disorders, and the genetic and epigenetic factors of tic disorders are consider...
Transdiagnostic Associations between Anger Hostility and Chemokine Interferon-gamma Inducible Protein 10 [0.03%]
愤怒敌对与细胞因子干扰素诱导的蛋白10的跨诊断关联研究
Hedda Soloey-Nilsen,Kristin Nygaard-Odeh,Magnhild Gangsoey Kristiansen et al.
Hedda Soloey-Nilsen et al.
Objective: Many psychiatric disorders are linked to low grade systemic inflammation as measured by systemic cytokine levels. Exploration of cytokines and immune activity and their role in psychiatric symptoms may inform p...
Association between Maternal Personality Traits and Children's Sleep Disturbance: A Population-based Cohort Study in Republic of Korea [0.03%]
基于韩国人群的队列研究:母亲人格特质与儿童睡眠障碍之间的关系
Ki Hyeon Kwak,Yunhye Oh
Ki Hyeon Kwak
Objective: Sleep affects the development and severity of psychiatric symptoms in children, and maternal personality traits may influence children's sleep. We aimed to confirm the longitudinal effect of maternal personalit...
The Dropout Rates and Associated Factors in Patients with Mood Disorders in Long-term Naturalistic Treatment [0.03%]
长期自然状态下心境障碍患者的脱落率及其影响因素
Wooyoung Jung,Eunsoo Moon,Hyun Ju Lim et al.
Wooyoung Jung et al.
Objective: Although maintenance treatment for mood disorders is important, the treatment discontinuation rate is reported to be high. This study aimed to investigate the dropout rates and associated factors in mood disord...
Effect of Frailty on Depression among Patients with Late-life Depression: A Test of Anger, Anxiety, and Resilience as Mediators [0.03%]
虚弱对晚年抑郁症患者抑郁的影响:愤怒、焦虑和复原力作为中介因素的作用机制分析
Junhyung Kim,Hyun-Ghang Jeong,Moon-Soo Lee et al.
Junhyung Kim et al.
Objective: While the association between depression and frailty in the elderly population has been investigated, the psychological factors that mediate such a relationship remain unknown. The identification of psychologic...
Augmentation Strategies for Partial or Non-responders to Clozapine in Patients with Schizophrenia: A Bayesian Network Meta-analysis of Randomized Controlled Trials [0.03%]
氯氮平部分或无反应的精神分裂症患者的增效策略:随机对照试验的贝叶斯网络meta分析
Archana Mishra,Rituparna Maiti,Biswa Ranjan Mishra et al.
Archana Mishra et al.
Clozapine is the only approved drug for treatment-resistant schizophrenia, but the response to the drug is often inadequate. Augmentation with other antipsychotics, anticonvulsants, and antidepressants is recommended for such patients, but ...
Current Understanding on Psilocybin for Major Depressive Disorder: A Review Focusing on Clinical Trials [0.03%]
裸盖菇素治疗抑郁症的临床试验研究进展综述
Sheng-Min Wang,Sunghwan Kim,Won-Seok Choi et al.
Sheng-Min Wang et al.
Previous studies suggested effectiveness of psilocybin in the field of mental health. FDA designated psilocybin as a "breakthrough therapy" for the treatment of treatment-resistant depression (TRD) in 2018. This paper provided a review of p...
Junsoo Chung,Young-Chan Kim,Jong-Hyun Jeong
Junsoo Chung
Sleep disturbance and abnormal circadian rhythm might be closely related to bipolar disorder. Several studies involving disturbed sleep/wake cycle, changes in rhythms such as melatonin and cortisol, clock genes, and circadian preference hav...
Alessandro Serretti
Alessandro Serretti
For the first time after many decades, many new antidepressants have been approved and many more are under various stages of development and will soon be available in the market. The new drugs present a range of new mechanisms of action wit...