Peripheral Blood-Derived Mesenchymal Stem Cells: Growth Factor-Free Isolation, Molecular Characterization and Differentiation [0.03%]
无血清条件分离的人外周血源间充质干细胞的分子特征及分化能力分析
Noushin Ouryazdanpanah,Shahriar Dabiri,Ali Derakhshani et al.
Noushin Ouryazdanpanah et al.
Background and objectives: The mesenchymal stem cells derived from peripheral blood (PB) have been recognized as a promising source for allogeneic cell therapy. The aim of this study was to investigate the isolation, grow...
Seyedeh Mehrnaz Kouhbananinejad,Farzaneh Armin,Shahriar Dabiri et al.
Seyedeh Mehrnaz Kouhbananinejad et al.
Background and objective: In recent years, due to increasing number of patients with non-healing skin ulcers, skin substitutes have been used. Skin substitutes contain living cells causing faster and more effective wound ...
Relationship Between PIK3CA Amplification and P110α and CD34 Tissue Expression as Angiogenesis Markers in Iranian Women with Sporadic Breast Cancer [0.03%]
PIK3CA扩增与P110α及CD34在散发性乳腺癌伊朗女性组织表达之间的关系（作为血管生成标记）
Shadi Hosseini,Farkhondeh Behjati,Maryam Rahimi et al.
Shadi Hosseini et al.
Background and objective: The PI3K/AKT/mTOR pathway is known to play an important role in regulating angiogenesis both in normal and breast cancer (BC) tissues. PIK3CA amplification was reported in various malignancies, i...
Evaluation of the CD123 Expression and FLT3 Gene Mutations in Patients with Acute Myeloid Leukemia [0.03%]
急性髓系白血病患者CD123表达及FLT3基因突变检测分析
Akbar Safaei,Ahmad Monabati,Maral Mokhtari et al.
Akbar Safaei et al.
Background and objective: Identification of cytogenetic and molecular changes plays an important role in acute myeloid leukemia (AML) patients. Thus, they are used in classification, prognosis and treatment of the disease...
Investigation of the rpoB Mutations Causing Rifampin Resistance by Rapid Screening in Mycobacterium Tuberculosis in North-East of Iran [0.03%]
伊朗东北部结核分枝杆菌rpoB基因突变导致利福平耐药性快速筛查研究
Amir Tajbakhsh,Faezeh Ghasemi,Seyedeh Zohre Mirbagheri et al.
Amir Tajbakhsh et al.
Background and objectives: The incidence of rifampin-resistant strains of Mycobacterium tuberculosis has attracted more attention than the tuberculosis infection due to laborious treatment and control. Recognizing the Myc...
Navid Bazzaz,Nazila Nouraee,Ali Zare-Mirzaie et al.
Navid Bazzaz et al.
Background and objective: Wilms' tumor (WT) is the most common genitourinary tract tumor in children. MicroRNAs (miRNAs) are small non-coding RNAs; their role in the pathogenesis of many types of human cancers has been id...
Molecular Status of BRAF Mutation in Prostate Adenocarcinoma: The Analysis of 100 Cases in North-East of IRAN [0.03%]
伊朗东北部100例前列腺腺癌标本中BRAF突变状态分析
Amir Hossein Jafarian,Khatoone Mirshekar Nasirabadi,Sare Etemad et al.
Amir Hossein Jafarian et al.
Background and objective: BRAF mutations were studied in various populations for prostate carcinoma (PC); however, mutations in BRAF gene are unusual compared to KRAS. Oncogenic activating of BRAF mutations were studied l...
The Effect of Cadmium on Apoptotic Genes mRNA Expression of Bax and Bcl-2 in Small Intestine of Rats [0.03%]
镉对大鼠小肠Bax和Bcl-2基因mRNA表达的影响
Narjes Seid Alian,Parvin Khodarahmi,Vahid Naseh
Narjes Seid Alian
Background & objective: Cadmium is a potent toxicant and carcinogenic substance for human and experimental animals. The evidences indicate that cadmium induces aberrant gene expression, inhibition of DNA damage repair, an...
Designing and Construction of a Cloning Vector Encoding mtb32C and mpt51 Fragments of Mycobacterium tuberculosis as a DNA Vaccine Candidate [0.03%]
设计并构建一个克隆载体作为结核分枝杆菌mtb32c和mpt51片段的dna疫苗候选物
Faria Hasanzadeh Haghighi,Ehsan Aryan,Mohammad Derakhshan et al.
Faria Hasanzadeh Haghighi et al.
Background & objective: Tuberculosis (TB) remains a major cause of death around the world. Bacillus Calmette Guérin (BCG) is the only vaccine used in TB prevention that has a protective effect in children, but its effect...
Prevalence of MPL (W515K/L) Mutations in Patients with Negative-JAK2 (V617F) Myeloproliferative Neoplasm in North-East of Iran [0.03%]
伊朗东北部负JAK2（V617F）骨髓增殖性肿瘤患者中MPL（W515K / L）突变的患病率
Seyyede Fatemeh Shams,Hossein Ayatollahi,Mohammad Hadi Sadeghian et al.
Seyyede Fatemeh Shams et al.
Background and objective: Janus kinase 2 (JAK2) and Myeloproliferative Leukemia (MPL) mutations are confirmatory indicators for Myeloproliferative Neoplasm (MPN). The current study was performed to determine the frequency...