Targeting Trefoil Factor Family 3 in Obstructive Airway Diseases: A Computational Approach to Novel Therapeutics [0.03%]
计算导向针对Trefoil因子家族3在阻塞性气道疾病中的作用研发新型药物治疗方法
Alireza Shahriary,Mohsen Sisakht,Masoud Arabfard et al.
Alireza Shahriary et al.
Background: Airway remodeling, a hallmark of chronic obstructive pulmonary disease (COPD) and mustard lung disease, is influenced by the Trefoil Factor 3 (TFF3). This study sought to pinpoint a compound with minimal toxic...
Effect of Video Games on Cognitive Performance and Problem-Solving Ability in the Aged with Cognitive Dysfunction: A Randomized Clinical Trial [0.03%]
视频游戏对认知障碍老年人的认知表现和解决问题能力的影响：一项随机临床试验
Mosayeb Mozafari,Masoumeh Otaghi,Maryam Paskseresht et al.
Mosayeb Mozafari et al.
Background: Mild cognitive impairment is a common aging phenomenon, and the absence of problem-solving abilities significantly contributes to memory decline. This study aimed to investigate the effect of video games on co...
Randomized Controlled Trial
Iranian journal of medical sciences. 2025 Feb 1;50(2):77-86. DOI:10.30476/ijms.2024.101861.3452 2025
Pulmonary Valve Replacement Using an Intraoperatively Created Trileaflet Autologous Pericardial Valve: A Case Series [0.03%]
术中利用自体心包构建三叶瓣行肺动脉瓣置换的病例系列报告
Ahmad Ali Amirghofran,Kamran Jamshidi,Mohammadreza Edraki et al.
Ahmad Ali Amirghofran et al.
Background: Pulmonary valve replacement is inevitable for the majority of patients with long-standing pulmonary regurgitation. The purpose of this study was to describe the experience of employing a novel technique to cre...
The Role of Memory T-Cell Mediated Immunity in Long-term COVID-19: Effects of Vaccination Status [0.03%]
记忆T细胞介导的免疫在长期COVID-19中的作用：疫苗状态的影响
Saulesh S Kurmangaliyeva,Akzhan M Madenbayeva,Saltanat T Urazayeva et al.
Saulesh S Kurmangaliyeva et al.
T-cell-mediated immunity is essential for controlling severe acute respiratory syndrome coronavirus 2 (SARSCoV2) infection, preventing severe disease, and potentially reducing the risk of long-term coronavirus disease (COVID). This study in...
The Effect of Estradiol and Testosterone Levels Alone or in Combination with Their Receptors in Predicting the Severity of Systemic Lupus Erythematosus: A Cohort Study [0.03%]
雌二醇和睾酮水平单独或与它们的受体结合预测系统性红斑狼疮严重程度的作用：队列研究
Samaneh Abdolahpour,Nafiseh Abdolahi,Mehrdad Aghaei et al.
Samaneh Abdolahpour et al.
Background: Developing a practical method to predict active systemic lupus erythematosus (SLE) in patients with inactive/mild status at the onset of the disease could lead to appropriate treatment that ultimately prevents...
Enhancing Medical Education with AI-Generated Visual Art: Benefits and Challenges [0.03%]
利用AI生成的视觉艺术提升医学教育：优势与挑战
Manica Negahdaripour,Mohammad Hasan Keshavarzi,Mitra Amini
Manica Negahdaripour
The Insulin-Producing Cells Generated from Rat Adipose Tissue Mesenchymal Stem Cells via Pdx1 Overexpression Activate an Immune Response both in Vitro and in Vivo [0.03%]
过表达Pdx1生成的大鼠脂肪组织间充质干细胞来源的胰岛素产生细胞在体内外均激活免疫反应
Shadab Mohammadian,Seyed Javad Hosseni,Fereshte Negad Dehbashi et al.
Shadab Mohammadian et al.
Background: The current work investigated the immunological features of insulin-producing cells (IPCs) generated from rat adipose-derived mesenchymal stem cells (ADSCs) both in vitro and in vivo. ...
Spontaneous Hemoperitoneum Caused by Malignant Gastrointestinal Stromal Tumor: A Case Report [0.03%]
恶性胃肠道间质瘤导致的自发性血腹症：病例报道
Nivetha Munuswamy,Pola Govardhan Kumar,Rajendran Shanmugasundaram et al.
Nivetha Munuswamy et al.
Gastrointestinal stromal tumors (GIST) are less prevalent mesenchymal tumors, accounting for 1% of gastrointestinal malignancies. Spontaneous hemoperitoneum (SH) following gastric GIST rupture is a rare occurrence. The present study describ...
Pharmacogenomics-Based Detection of Variants Involved in Pain, Anti-inflammatory and Immunomodulating Agents Pathways by Whole Exome Sequencing and Deep in Silico Investigations Revealed Novel Chemical Carcinogenesis and Cancer Risks [0.03%]
基于药理基因组学的全外显子测序和深入的计算研究发现参与疼痛，抗炎和免疫调节剂通路的变异及新型化学致癌和癌症风险
Alireza Sharafshah,Majid Motovali-Bashi,Parvaneh Keshavarz
Alireza Sharafshah
Background: Next-Generation Sequencing (NGS) methods specifically Whole-Exome Sequencing (WES) have demonstrated promising findings with a high accuracy of 91%-99% in Pharmacogenomics (PGx). A PGx-based panel can be utili...
Advancing Multiple Myeloma Immunotherapy: A Review of Chimeric Antigen Receptor T-Cell and Bispecific T-Cell Engagers Cell Therapies in Revolutionizing Treatment [0.03%]
多发性骨髓瘤免疫治疗进展：CAR-T细胞和双特异性T细胞衔接器细胞疗法在革命性治疗中的回顾
Rahul Navab,Pragyat Futela,Verkha Kumari et al.
Rahul Navab et al.
Multiple Myeloma (MM) is a hematologic malignancy characterized by clonal plasma cell development, leading to serious complications. Despite traditional treatments, MM remains incurable, necessitating innovative therapeutic approaches. Chim...