Efficacy, safety, and immunogenicity of UB-851 versus Eprex® in patients with renal anemia receiving hemodialysis: A randomized, double-masked, phase III trial [0.03%]
UB-851与Eprex在透析患者肾性贫血中的疗效、安全性和免疫原性的III期双盲随机研究
Chien-Hsing Wu,Chih-Chung Shiao,Hsien-Yi Wang et al.
Chien-Hsing Wu et al.
Background: Anemia is a common complication in patients with chronic kidney disease (CKD), for which recombinant human erythropoietin (rhEPO) is the standard treatment. UB-851 is a biosimilar rhEPO developed as an alterna...
One stop shop-Integrating 18F-PSMA-1007 and 11C-acetate PET with multiparametric MRI imaging for prostate cancer: A prospective study [0.03%]
一站式检查:将18F-PSMA-1007和11C醋酸PET与多参数MRI成像相结合用于前列腺癌检测:一项前瞻性研究
Ko-Han Lin,Shu-Huei Shen,William Ji-Shien Huang et al.
Ko-Han Lin et al.
Background: To evaluate the diagnostic performance and clinical utility of integrating 18F-PSMA-1007 PET, 11C-acetate PET, and multiparametric MRI (mpMRI) in a one-stop-shop PET/MRI protocol for intermediate- to high-risk...
Machine-learning-based decision-tree model for patients with single-large hepatocellular carcinoma [0.03%]
基于机器学习的单个大肝细胞癌患者的决策树模型
Yi-Chen Lin,Chun-Ting Ho,Pei-Chang Lee et al.
Yi-Chen Lin et al.
Background: Single-large hepatocellular carcinoma (SLHCC) is defined as a solitary tumor that is larger than 5 cm and lacks macrovascular invasion or extrahepatic spread. SLHCC is a distinct clinical subtype with consider...
Comparison of treatment options with long intramedullary nail and dynamic hip screws for metastatic subtrochanteric fracture: A cohort study [0.03%]
治疗长期内固定钉与动力髋螺钉治疗转移性转子下骨折的比较:群组研究
Ke-Chin Chou,Kun-Han Lee,Chao-Ming Chen et al.
Ke-Chin Chou et al.
Background: Pathological subtrochanteric fractures pose challenges due to the high biomechanical demands of this region and the systemic complexity of metastatic disease. At present, the optimal fixation method remains co...
Shared neural network dysfunctions in treatment-resistant major depression and alcohol use disorder: Resting-state fMRI evidence and implications for neuromodulation [0.03%]
难治性抑郁症和酒精使用障碍的共享神经网络功能异常:静息态功能磁共振成像证据及对神经调控的意义
Yun Tien,Cheng-Ta Li
Yun Tien
Treatment-resistant depression (TRD) and alcohol use disorder (AUD) frequently coexist, complicating clinical management and contributing to poor outcomes. Despite their distinct clinical presentations, converging neuroimaging evidence indi...
Development of extracellular vesicles in diagnostics and therapeutics: From extracellular vesicles to precision medicine [0.03%]
从外泌体到精准医疗:外泌体在诊断和治疗中的发展
Yuan-Jen Tsai,Yi-Hsueh Liao
Yuan-Jen Tsai
Extracellular vesicles (EVs) are membrane-bound vesicles released by various cell types and contain biologically active molecules that participate in key physiological and pathological processes. EVs play crucial roles in intercellular comm...
Method for accessing zygomatic-maxillary complex symmetry: Mirroring, transposing and calculating Hausdorff distance [0.03%]
基于豪斯多夫距离的颧弓-上颌复合体对称性分析方法研究
Tien-Hsiang Wang,Yu-Chung Shih,Wen-Chan Yu et al.
Tien-Hsiang Wang et al.
Background: The primary goal of facial fracture treatment is to restore both functional integrity and aesthetic harmony. However, achieving optimal outcomes remains challenging due to the complex facial anatomy and the re...
There are currently no appropriately designed studies that demonstrate a link between vitamin-D levels and the COVID-19 severity [0.03%]
目前尚无设计合理的研究证明维生素D水平与新冠肺炎病情严重程度之间存在关联
Hinpetch Daungsupawong,Viroj Wiwanitkit
Hinpetch Daungsupawong
Early anatomical outcomes of faricimab vs. aflibercept 2 mg in treatment-naïve neovascular AMD and PCV: A head-to-head comparative study in Taiwan [0.03%]
法瑞西姆与阿柏西普治疗中国台湾特发性湿性年龄相关性黄斑变性和息肉状脉络膜血管病变的早期解剖学结果:头对头比较研究
Chi-Chun Yang,Chang-Chi Weng,Yu-Bai Chou et al.
Chi-Chun Yang et al.
Background: While clinical trials have established the non-inferiority of faricimab compared to aflibercept regarding 1-year visual acuity, real-world evidence directly comparing their early effects on anatomical changes ...
Programmed death-ligand 1 (PD-L1) upregulation is associated with poor prognosis in patients with epithelial ovarian cancer [0.03%]
程序性死亡配体1(PD-L1)上调与上皮性卵巢癌患者的不良预后相关
Chia-Hao Liu,Wei-Ting Chao,Szu-Ting Yang et al.
Chia-Hao Liu et al.
Background: The clinical significance of programmed death-ligand 1 (PD-L1) expression in epithelial ovarian cancer (EOC), particularly its association with platinum resistance (PR) and prognosis, remains unclear. This stu...