[Hypoxia-Inducible Factor Prolyl Hydroxylase Enzyme Inhibitors: A Novel Therapy for Anemia Treatment in CKD Patients] [0.03%]
[缺氧诱导因子脯氨酰羟化酶抑制剂——治疗CKD相关性贫血的新型药物]
Andrea Stucchi,Lorenza Magagnoli,Anila Cara et al.
Andrea Stucchi et al.
Anemia is a major complication of chronic kidney disease (CKD). Its prevalence increases with advancing age and progression of kidney disease. The main cause of anemia linked to CKD is represented by the reduction erythropoietin secretion. ...
[Almost Forty Years of Erythropoietin Therapy: Successes and Limitations] [0.03%]
[几乎40年的促红细胞生成素治疗：成功与局限性]
Lucia Del Vecchio,Giulio Pucci Bella,Francesco Locatelli
Lucia Del Vecchio
Anaemia is a frequent complication of chronic kidney disease; if severe and untreated, it leads to a worsening of quality of life and an increased risk of resorting to haemotransfusions. Beginning with studies in physio-pathology that began...
Chiara Carla Maria Brunati,Davide Barraco,Francesco Munforte et al.
Chiara Carla Maria Brunati et al.
Iron therapy in nephropathic patients can allow optimizing treatment with EPO identifying the minimum effective dose capable of improving the patient's quality of life. The most recent studies on iron metabolism and on the interference of i...
Marco Manganaro
Marco Manganaro
Numerous studies have shown that hyperuricemia (HU) is an independent risk factor for the development of chronic kidney disease (CKD) and cardiovascular events. However, while some evidence suggests that uric acid (UA) may play not only a p...
[Effects of Finerenone on Proteinuria and Progression of Chronic Kidney Disease] [0.03%]
非洛nitron对蛋白尿及慢性肾脏病进展的影响
Antonio De Pascalis,Giuseppe Cianciolo,Alessandro Tommassetti et al.
Antonio De Pascalis et al.
A growing body of experimental and clinical evidence confirms that aldosterone contributes, independently from its classical homeostatic effects, to the pathogenesis and progression of chronic kidney disease (CKD). In fact, the activation o...
Simona Barbuto,Veronica Catalano,Marianna Pira et al.
Simona Barbuto et al.
In recent years, the prevalence of chronic kidney disease (CKD) has significantly increased, with an estimated 843.6 million individuals affected in 2017 [1]. This rise is closely linked to the growing incidence of risk factors such as diab...
Filippo Aucella,Rachele Grifa,Francesco Aucella et al.
Filippo Aucella et al.
The renin-angiotensin-aldosterone (RAAS) system plays a significant role in renal and cardiovascular pathophysiology, since its increased activity is involved in arterial hypertension, heart failure, and kidney disease. ACEIs and ARBs are e...
The Effect of Dialysate Temperature on Dialysis Adequacy and Hemodynamic Stability: An Experimental Study with Crossover Design [0.03%]
透析液温度对 dialysis adequacy 和血流动力学稳定性的影响：一种交叉设计实验研究
Gerry George Mathew,Suganya Muthukarupiah,Muthamizh Muniappan et al.
Gerry George Mathew et al.
Cool dialysate has variable impact on hemodynamic stability and dialysis adequacy. Hemodynamic stability and dialysis adequacy are crucial indicators for better life expectancy and cardiovascular mortality. This research aims to evaluate th...
Carlos G Musso,Rossina Juarez,W Belloso et al.
Carlos G Musso et al.
Introduction. Renal functional reserve (RFR) is the kidney capability of increasing its basal glomerular filtration rate (GFR) at least 20% after an adequate stimulus. Renal disorders have been reported in seropositive HIV patients, particu...
Giuseppe Gatta,Antonio Scarlatella,Francesco Aucella et al.
Giuseppe Gatta et al.
The arteriovenous fistula (AVF) represents the favorite vascular access in individuals with chronic kidney disease (CKD). Because AVF is a guarantee of survival for these patients, proper surgical packing and a timely follow-up program is c...