Validity of perinatal pharmacoepidemiologic studies using data from the RAMQ administrative database [0.03%]
基于RAMQ管理数据库的围生期药物流行病学研究的可靠性分析
Anick Bérard,Anaïs Lacasse
Anick Bérard
Background: The RAMQ prescription claims database (RAMQ-Rx) is increasingly being used in perinatal pharmacoepidemiologic studies; but, there are reasons to believe that results generated with the RAMQ-Rx might not be gen...
The unintended (and costly) effects due to the introduction of an unrestricted reimbursement policy for atypical antipsychotic medications in a Canadian public prescription drug program: 1996/97 to 2005/06 [0.03%]
加拿大公共处方药项目引入非典型抗精神病药物无限制报销政策的意外后果（及其代价）：1996/97至2005/06年度
Daria J O&#x;Reilly,Ron A Goeree,Jean-Eric Tarride et al.
Daria J O&#x;Reilly et al.
Background: Due to the increasing costs of pharmaceuticals, drug benefit programs often implement various policies that limit availability of drugs. These policies can have unforeseen consequences. ...
Cost-effectiveness of intensive lipid lowering therapy with 80 mg of atorvastatin, versus 10 mg of atorvastatin, for secondary prevention of cardiovascular disease in Canada [0.03%]
在加拿大用于继发性心血管疾病预防的高强度辛伐他汀（阿托伐他汀80毫克）与低强度辛伐他汀（阿托伐他汀10毫克）治疗的效用比评估
Monika Wagner,Mireille Goetghebeur,Elizabeth Merikle et al.
Monika Wagner et al.
Background: The TNT study compared high dose atorvastatin (80 mg) versus moderate atorvastatin (10 mg) treatment in 10,001 patients with stable coronary heart disease (CHD), over 4.9 years. Intensive lipid-lowering with a...
Access and intensity of use of prescription analgesics among older Manitobans [0.03%]
曼尼托巴老年人使用处方止痛药的情况及用药强度
Cheryl A Sadowski,Anita G Carrie,Ruby E Grymonpre et al.
Cheryl A Sadowski et al.
Background: Under-treatment of pain is frequently reported, especially among seniors, with chronic non-cancer pain most likely to be under-treated. Legislation regarding the prescribing/dispensing of opioid analgesics (in...
Were our forebears aware of prenatal alcohol exposure and its effects? A review of the history of fetal alcohol spectrum disorder [0.03%]
我们的先辈意识到宫内酒精暴露及其影响了吗？一篇关于胎儿酒精谱系障碍历史的综述文章
James L Sanders
James L Sanders
Many historical records have been taken out of context when reviewing the history of prenatal alcohol exposure, and the impacts of these histories on modern-day FASD research have been overestimated. Historical records, as early as biblical...
Evidence and values: requirements for public reimbursement of drugs for rare diseases--a case study in oncology [0.03%]
证据与价值：罕见病药物公共补偿的要求--一个肿瘤学的案例研究
Michael Drummond,Bill Evans,Jacques LeLorier et al.
Michael Drummond et al.
Introduction: Doubts have been expressed about whether standard methods of health technology assessment are suitable for the evaluation of drugs for rare diseases. Under conditions of rarity, it may be more difficult to c...
Control of esophageal and intragastric pH with compounded and manufactured omeprazole in patients with reflux esophagitis: a pilot study [0.03%]
奥美拉唑散剂和片剂对胃食管反流病患者食道及胃内pH值控制的对比研究：一项初步研究
Luciana D Moretzsohn,Emanuella B Carvalho,Junia D Franco et al.
Luciana D Moretzsohn et al.
Background: Proton pump inhibitors (PPI) are the drugs of choice for treatment of gastroesophageal reflux disease (GERD). Omeprazole, the first PPI commercialized, is now available in different formulations. ...
Randomized Controlled Trial
The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique. 2009 Winter;16(1):e264-72. DOI: 2009
Screening and recording of alcohol use among women of child-bearing age and pregnant women [0.03%]
育龄妇女和孕妇的饮酒筛查与记录
Moumita Sarkar,Margaret Burnett,Sarah Carrière et al.
Moumita Sarkar et al.
A woman's alcohol use during pregnancy is one of the top preventable causes of birth defects and developmental disabilities that are known as fetal alcohol spectrum disorders (FASD). The social and economic burden of FASD is substantial. Li...
Concordance of three methods for palpebral fissure length measurement in the assessment of fetal alcohol spectrum disorder [0.03%]
三种上眼睑裂长度测量方法在胎儿酒精谱系障碍评估中的一致性分析
Meghan E Cranston,Aizeddin A Mhanni,Sandra L Marles et al.
Meghan E Cranston et al.
Background: The assessment of individuals at risk of fetal alcohol spectrum disorders (FASD) includes the assessment of the craniofacial features that can result from prenatal alcohol exposure. The characteristic facial f...