X-Y Fu,X-D Dong,L Zeng et al.
X-Y Fu et al.
The identification of oncogenic drivers and the subsequent development of targeted therapies have been established as biomarker-based care for metastatic non-small cell lung cancer (NSCLC) patients. Rearranged during transfection (RET) even...
Clinical development and current role of margetuximab for the treatment of breast cancer [0.03%]
Margatumab的临床开发及其在乳腺癌治疗中的作用
P Tarantino,J Uliano,S Morganti et al.
P Tarantino et al.
Up to 20% of breast cancers overexpress HER2, a molecular alteration conferring these tumors a particularly aggressive behavior. However, targeting HER2 has radically changed the prognosis of this disease in the last 2 decades, with multipl...
A Becciolini,E Di Donato,D Santilli et al.
A Becciolini et al.
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation and progressive disability when inflammation cannot be sufficiently controlled. Despite treatment with conventional synthetic disease-modifying an...
T Yamamoto
T Yamamoto
Pyoderma gangrenosum is a refractory disease characterized by chronic ulcers, presenting with central deep ulceration and undermined borders predominantly involving the lower extremities. Oral prednisolone and/or cyclosporine has been consi...
International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Annual Meeting (May 17-20, 2021 - Virtual Meeting) [0.03%]
国际药物经济学与结果研究协会(ISPOR)年度大会(2021年5月17-20日，线上会议)
A Kibble
A Kibble
COVID-19 has pushed us to think differently about health and its delivery, and following the declaration of pandemic by the World Health Organization (WHO), value chains have been largely broken and must be rebuilt and redesigned. COVID-19 ...
Vibegron: a β3-adrenergic agonist for the treatment of overactive bladder [0.03%]
Vibegron：一种β3-肾上腺素受体激动剂，用于治疗膀胱过度活动症
D M Paton
D M Paton
Overactive bladder (OAB) is an extremely common condition in adults of both sexes. It is characterized by an urgent need to micturate often accompanied by incontinence. The condition may also increase the number of micturitions in a 24-hour...
Razumab -- the role of biosimilars for the treatment of retinal diseases [0.03%]
瑞苏玛布-生物仿制药在视网膜疾病治疗中的作用
L Ferro Desideri,C A Cutolo,C E Traverso et al.
L Ferro Desideri et al.
Biologics targeting vascular endothelial growth factor (anti-VEGF) are the mainstay treatment of many vascular retinal pathologies. To date, Razumab is the only approved biosimilar for ophthalmic use. Razumab showed no differences compared ...
K Fukui,T Tanaka,M Nangaku
K Fukui
Anemia is a common complication in patients with chronic kidney disease (CKD). Erythropoiesis-stimulating agents (ESAs) are the standard therapy for anemia in CKD. It has been expected that hypoxia-inducible factor prolyl hydroxylase (HIF-P...
Atoltivimab/maftivimab/odesivimab (Inmazeb) combination to treat infection caused by Zaire ebolavirus [0.03%]
阿托利珠单抗/马特利珠单抗/奥塞瑞珠单抗（Inmazeb）组合疗法治疗埃博拉病毒病感染
D Saxena,G Kaul,A Dasgupta et al.
D Saxena et al.
Zaire ebolavirus has been responsible for several catastrophic outbreaks with a high mortality rate. Unfortunately, there were no approved therapies or vaccines to treat or prevent infections caused by Ebola virus (EBOV) or other filoviruse...
Role of nitazoxanide as a repurposed drug in the treatment and management of various diseases [0.03%]
硝唑尼德在各种疾病的治疗和管理中的再利用作用分析
Charu Bharti,Shrestha Sharma,Nitin Goswami et al.
Charu Bharti et al.
Nitazoxanide (NTZ) is an orally active drug with significant postmarketing experience including more than 75 million adults and children. Presently, this drug is widely used for a number of infectious conditions and diseases. It has a wide ...