Hila Haskelberg,Andrew Carr,Sean Emery
Hila Haskelberg
Biomarkers are being increasingly used in basic and clinical research of HIV disease as well as clinical management of infected individuals. Bone metabolism can be assessed by measurement of bone turnover markers, molecules released during ...
Review
AIDS reviews. 2011 Oct-Dec;13(4):240-50. DOI: 2011
James B Whitney,So-Yon Lim,Mark A Wainberg
James B Whitney
Retroviruses are known to exhibit remarkable genomic pliancy, a capacity that has been attributed to one or more error prone steps in the viral replication cycle. However, increasing evidence suggests that such error represents a key elemen...
Review
AIDS reviews. 2011 Oct-Dec;13(4):234-9. DOI: 2011
Protease inhibitors as preferred initial regimen for antiretroviral-naive HIV patients [0.03%]
初治艾滋病患者抗逆转录病毒治疗首选蛋白酶抑制剂方案
Francisco Tejerina,Juan Carlos López Bernaldo de Quirós
Francisco Tejerina
At present, the majority of patients who have initiated their first antiretroviral therapy have received a combination comprising a nonnucleoside and two nucleoside analogues. The use of nonnucleosides as first-line therapy has been favored...
Review
AIDS reviews. 2011 Oct-Dec;13(4):227-33. DOI: 2011
HIV drug resistance assessment in the Western Pacific region. A systematic review [0.03%]
西太平洋地区艾滋病药物抗性评估的系统回顾
Dongbao Yu,Donald Sutherland,Massimo Ghidinelli et al.
Dongbao Yu et al.
Antiretroviral therapy is being rapidly scaled-up in Western Pacific region countries. Prevention and assessment of HIV drug resistance is an essential component of successful global antiretroviral therapy scale-up. We performed a systemati...
Review
AIDS reviews. 2011 Oct-Dec;13(4):214-26. DOI: 2011
Current treatment strategies, complications and considerations for the use of HIV antiretroviral therapy during pregnancy [0.03%]
人类免疫缺陷病毒抗逆转录病毒药物在妊娠期间应用的当前治疗策略、并发症及注意事项
Jorge F Senise,Adauto Castelo,Marisol Martínez
Jorge F Senise
The global prevalence of HIV infection in the female population presents a significant healthcare burden in terms of mother-to-child transmission (MTCT) of the disease. This review aims to discuss current trends and treatment guidelines for...
Review
AIDS reviews. 2011 Oct-Dec;13(4):198-213. DOI: 2011
Antiretroviral salvage therapy for multiclass drug-resistant HIV-1-infected patients: from clinical trials to daily clinical practice [0.03%]
多重耐药的人类免疫缺陷病毒-1感染患者的抗逆转录病毒治疗：从临床试验到常规实践
Arkaitz Imaz,Vicenç Falcó,Esteban Ribera
Arkaitz Imaz
Drug resistance is one of the key problems in the management of long-term HIV-1-infected patients. Due to cross-resistance patterns within classes, broad resistance to the three original antiretroviral classes can develop in some patients, ...
Review
AIDS reviews. 2011 Jul-Sep;13(3):180-93. DOI: 2011
Diagnosis and clinical features of major neuropsychiatric disorders in HIV infection [0.03%]
HIV感染中的主要神经精神障碍的诊断和临床特征
Lucía Gallego,Pablo Barreiro,Juan José López-Ibor
Lucía Gallego
The prevalence of neuropsychiatric disorders is high in HIV-infected individuals. Despite being frequent, these disorders are often underdiagnosed and undertreated. Many of these conditions show differential clinical features as compared wi...
Review
AIDS reviews. 2011 Jul-Sep;13(3):171-9. DOI: 2011
Prospects for the management of human T-cell lymphotropic virus type 1-associated myelopathy [0.03%]
人类T细胞淋巴瘤病毒I型相关脊髓病的管理展望
Fabiola Martin,Graham P Taylor
Fabiola Martin
Over the twenty-five years since the association of human T-cell lymphotropic virus type 1 infection with tropical spastic paraparesis, little progress has been made in the treatment of this chronic debilitating condition. The purpose of th...
Review
AIDS reviews. 2011 Jul-Sep;13(3):161-70. DOI: 2011
Mechanisms of RNA interference in the HIV-1-host cell interplay [0.03%]
RNA干扰在人类免疫缺陷病毒类型1与宿主细胞互作中的作用机制研究进展
María Sánchez-Del Cojo,María Rosa López-Huertas,Elena Mateos et al.
María Sánchez-Del Cojo et al.
The RNA interference pathway is a mechanism to regulate gene expression that acts in mammalian antiviral immunity as a complement of interferon- and cytokine-based innate immunity. RNA interference has been proposed as an ancient mechanism ...
Review
AIDS reviews. 2011 Jul-Sep;13(3):149-60. DOI: 2011
Paul W Denton,J Víctor García
Paul W Denton
Because of the limited tropism of HIV, in vivo modeling of this virus has been almost exclusively limited to other lentiviruses, such as simian immunodeficiency virus, that reproduce many important characteristics of HIV infection. However,...
Review
AIDS reviews. 2011 Jul-Sep;13(3):135-48. DOI: 2011