Sphingosine-1-Phosphate Induces the Migration and Angiogenesis of Epcs Through the Akt Signaling Pathway via Sphingosine-1-Phosphate Receptor 3/Platelet-Derived Growth Factor Receptor-β [0.03%]
鞘氨醇-1-磷酸通过S1P受体3/血小板衍生生长因子受体-β轴的Akt信号通路诱导EPCs迁移和血管生成
Hang Wang,Ke-Yin Cai,Wei Li et al.
Hang Wang et al.
Endothelial progenitor cells (EPCs) play a fundamental role in neoangiogenesis and tumor angiogenesis. Through the sphingosine-1-phosphate receptor 3 (S1PR3), sphingosine-1-phosphate (S1P) can stimulate the functional capacity of EPCs. Plat...
Mechanical Strain Affects Some Microrna Profiles in Pre-Oeteoblasts [0.03%]
机械牵张影响软骨细胞分化前 osteoblast 前体细胞的某些 microRNA 分布状况
Yang Wang,Xianqiong Zou,Yong Guo et al.
Yang Wang et al.
MicroRNAs (miRNAs) are important regulators of cell proliferation, differentiation and function. Mechanical strain is an essential factor for osteoblast proliferation and differentiation. A previous study revealed that a physiological mecha...
Study strategies for long non-coding RNAs and their roles in regulating gene expression [0.03%]
长非编码RNA的研究策略及其对基因表达调控的作用
Dan Qin,Cunshuan Xu
Dan Qin
Long non-coding RNAs (lncRNAs) have attracted considerable attention recently due to their involvement in numerous key cellular processes and in the development of various disorders. New high-throughput methods enable their study on a genom...
Valter Lubrano,Morena Gabriele,Maria Rita Puntoni et al.
Valter Lubrano et al.
Previous studies evidenced a significant reduction in serum cholesterol levels during an episode of acute inflammation. The aim of the present study was to verify the hypothesis of a regulatory role of cytokines through an in vitro model th...
Identification of shorter length lamin A protein in mouse ear cartilage tissue [0.03%]
在小鼠耳软骨组织中鉴定较短的lamin A蛋白长度
Ramamoorthy M Kalidas,Subramanian Elaiya Raja,Sivasubramaniam Sudhakar
Ramamoorthy M Kalidas
Lamin A is an intermediate filament protein which is cleaved by the enzyme, FACE 1 at VTRSY↓L. The cleavage is the final step in the production of the mature lamin A protein. The mature lamin A protein localizes in the inner membrane of th...
Siti Nurbaya Oslan,Abu Bakar Salleh,Raja Noor Zaliha Raja Abd Rahman et al.
Siti Nurbaya Oslan et al.
Pichia guilliermondii strain SO isolated from spoiled orange was developed for use as an alternative expression host by using Pichia pastoris as the model of the experiment. This is the first study to report on the capability of P. guillier...
Rongqiang Yang,Xin Jiang,Rui Ji et al.
Rongqiang Yang et al.
Pituitary adenylate cyclase activating polypeptide (PACAP) is widely expressed in the central and peripheral nervous system. PACAP can initiate multiple signaling pathways through binding with three class B G-protein coupled receptors, PAC1...
Daria Głogocka,Magdalena Przybyło,Marek Langner
Daria Głogocka
Biological systems are characterized by directional and precisely controlled flow of matter and information along with the maintenance of their structural patterns. This is possible thanks to sequential transformations of information, energ...
The β-actin gene promoter of rohu carp (Labeo rohita) drives reporter gene expressions in transgenic rohu and various cell lines, including spermatogonial stem cells [0.03%]
罗非鱼（Labeo rohita）β-肌动蛋白基因启动子在转基因鱼及多种细胞系中的表达，包括精原干细胞
Hirak Kumar Barman,Ramya Mohanta,Swagat Kumar Patra et al.
Hirak Kumar Barman et al.
We previously characterized the β-actin gene promoter of Indian domesticated rohu carp (Labeo rohita) and made a reporter construct via fusion to green fluorescence protein (GFP) cDNA. In this study, the same construct was used to breed tr...
Is there a connection between inflammation, telomerase activity and the transcriptional status of telomerase reverse transcriptase in renal failure? [0.03%]
炎症与端粒酶活性及端粒酶逆转录酶转录状态在肾衰竭中的关系研究
Vasileios Kordinas,George Tsirpanlis,Chryssoula Nicolaou et al.
Vasileios Kordinas et al.
Telomerase is involved in the elongation of telomeres. It remains active in very few types of cell in mature organisms. One such cell type is the lymphocytes. In this study, we investigated the activity and expression of telomerase in lymph...