Maria Chiara Ditto,Marco Antivalle,Matteo Badini et al.
Maria Chiara Ditto et al.
The diagnosis of bacterial endocarditis remains a challenge, as nearly half of cases develop in the absence of preexistent heart disease and known risk factors. Not infrequently, a blunted clinical course at onset can lead to erroneous diag...
Risk factors for radiographic tibiofemoral knee osteoarthritis: the wuchuan osteoarthritis study [0.03%]
中国巫昌骨关节炎研究中的膝骨关节炎影像学因素分析
Jianhao Lin,Rujun Li,Xiaozheng Kang et al.
Jianhao Lin et al.
Objective. To investigate the risk factors of radiographic tibiafemoral knee osteoarthritis (OA). Methods. A population-based cross-sectional survey was conducted in Wuchuan County. A questionnaire and bilateral weight-bearing posterior-ant...
Is musculoskeletal ultrasonography an operator-dependent method or a fast and reliably teachable diagnostic tool? Interreader agreements of three ultrasonographers with different training levels [0.03%]
肌骨超声检查是一种依赖操作者的诊断方法还是一种快速且易于掌握的诊断工具？三种不同培训水平的超声医师之间的图像解读一致性研究
Sarah Ohrndorf,Lydia Naumann,Jessica Grundey et al.
Sarah Ohrndorf et al.
Objectives. To assess interreader agreements and a learning curve between three (senior, junior, and beginner) different experienced musculoskeletal ultrasonographers. Senior served as the imaging "gold standard". Methods. Clinically domina...
Successful Treatment of ANCA-Negative Wegener's Granulomatosis with Rituximab [0.03%]
利妥昔单抗治疗ANCA阴性的韦格纳肉芽肿病1例
Afsha Khan,Catherine A Lawson,Mark A Quinn et al.
Afsha Khan et al.
Wegener's Granulomatosis (WG) is a systemic vasculitis typically associated with antineutrophil cytoplasmic antibodies (ANCAs). A small proportion of patients are ANCA negative, however, and this is more commonly found in individuals with d...
Lorinda Chung,Oliver Distler,Laura Hummers et al.
Lorinda Chung et al.
Interleukin-6 as a potential therapeutic target for pulmonary arterial hypertension [0.03%]
白细胞介素-6作为肺动脉高压治疗靶点的潜在作用
Yoshiaki Furuya,Toru Satoh,Masataka Kuwana
Yoshiaki Furuya
Interleukin-6 (IL-6) is a pleiotropic cytokine with a wide range of biologic activities in immune regulation, hematopoiesis, inflammation, and oncogenesis. Recent accumulating evidence indicates a pathologic role for IL-6 in promoting proli...
Penile involvement in Systemic Sclerosis: New Diagnostic and Therapeutic Aspects [0.03%]
系统性硬化症的阴茎受累：新的诊断和治疗方面
Antonio Aversa,Roberto Bruzziches,Davide Francomano et al.
Antonio Aversa et al.
Systemic Sclerosis (SSc) is a connective tissue disorder featuring vascular alterations and an immunological activation leading to a progressive and widespread fibrosis of several organs such as the skin, lung, gastrointestinal tract, heart...
Ibrahim Batal,Robyn T Domsic,Thomas A Medsger et al.
Ibrahim Batal et al.
Scleroderma renal crisis (SRC) is an infrequent but serious complication of systemic sclerosis (SSc). It is associated with increased vascular permeability, activation of coagulation cascade, and renin secretion, which may lead to the acute...
Hiroshi Hashimoto
Hiroshi Hashimoto
AAV in SSc is described from the point of view of MPA. Some of reported SSc cases with AAV are thought to exhibit the characteristic clinical manifestations of MPA, although ANCA positivity in SSc is uncommon. MPA is clinically characterize...
Ann Julie Impens,James R Seibold
Ann Julie Impens
Sexual dysfunction is common in systemic sclerosis (SSc). Male erectile dysfunction (MED) has been reported in around 80% of subjects and more than half of female patients fulfill criteria for diagnosis as female sexual arousal Disorder (FS...