Shinji Maeda,Yoshihito Hayami,Taio Naniwa et al.
Shinji Maeda et al.
Psoriatic arthritis (PsA) is a chronic inflammatory skin disease that causes enthesitis and destructive arthritis and significantly lowers patient quality of life. Recognition of the two target organs (the skin and joints) involved in the i...
Biologicals [0.03%]
生物制品杂志
Jozélio Freire de Carvalho,Simone Appenzeller,Yehuda Shoenfeld
Jozélio Freire de Carvalho
Kazushige Uchida,Takeo Kusuda,Masanori Koyabu et al.
Kazushige Uchida et al.
Autoimmune pancreatitis (AIP) is a newly recognized pancreatic disorder. Recently, International Consensus Diagnostic Criteria for AIP (ICDC) was published. In this ICDC, AIP was classified into Type 1 and Type 2. Patients with Type 1 AIP h...
Shigeyuki Kawa,Tetsuya Ito,Takayuki Watanabe et al.
Shigeyuki Kawa et al.
IgG4-related disease is a new disease entity involving IgG4 in its clinical presentation and having 6 characteristic features: (1) systemic involvement; (2) solitary or multiple lesions showing diffuse or localized swelling, masses, nodules...
Dai Inoue,Yoh Zen,Yasuharu Sato et al.
Dai Inoue et al.
Aims. To elucidate characteristics of IgG4-related disease involving the peripheral nervous system. Methods. Retrospective review of 106 patients with IgG4-related disease identified 21 peripheral nerve lesions in 7 patients. Clinicopatholo...
The prevalence and clinical correlates of an auscultatory gap in systemic sclerosis patients [0.03%]
系统性硬化病患者的听诊差异流行率及临床相关因素
Tracy M Frech,Jason Penrod,Michael J Battistone et al.
Tracy M Frech et al.
Introduction. Accurate blood pressure (BP) measurement is essential to the diagnosis and management of hypertension in patients with systemic sclerosis (SSc) to help prevent renal and cardiovascular complications. The presence of an auscult...
TNF-Alpha in the Locomotor System beyond Joints: High Degree of Involvement in Myositis in a Rabbit Model [0.03%]
兔模型中肿瘤坏死因子α在关节外运动系统中的高度参与性炎症反应：肌肉炎症中的高涉及度
Sture Forsgren,Lina Renström,Craig Purdam et al.
Sture Forsgren et al.
The importance of TNF-alpha in arthritis is well documented. It may be that TNF-alpha is also markedly involved in muscle inflammation (myositis). An animal model where this can be investigated is needed. A newly developed rabbit myositis m...
Mariana Postal,Lilian Tl Costallat,Simone Appenzeller
Mariana Postal
Systemic lupus erythematosus (SLE) is a prototypic inflammatory autoimmune disorder characterized by multisystem involvement and fluctuating disease activity. Symptoms range from rather mild manifestations such as rash or arthritis to life-...
Risk of orthopedic surgical site infections in patients with rheumatoid arthritis treated with antitumor necrosis factor alfa therapy [0.03%]
抗肿瘤坏死因子α治疗的类风湿关节炎患者发生骨科手术部位感染的风险
Bernardo Matos da Cunha,Licia Maria Henrique da Mota,Leopoldo Luiz Dos Santos-Neto
Bernardo Matos da Cunha
Introduction. International guidelines recommend interruption of anti-TNF medications in the perioperative period, but there are no randomized trials to support such recommendation. Objectives. To study literature evidence assessing the ris...
Tocilizumab for the treatment of rheumatoid arthritis and other systemic autoimmune diseases: current perspectives and future directions [0.03%]
托珠单抗治疗类风湿关节炎及其他系统性自身免疫性疾病：现状及未来展望
Atsushi Ogata,Toshio Tanaka
Atsushi Ogata
Interleukin (IL)-6 is a cytokine featuring redundancy and pleiotropic activity. While IL-6, when transiently produced, contributes to host defense against acute environmental stress, continuous dysregulated IL-6 production plays a significa...