Abdo Lutf,Mohammed Hammoudeh
Abdo Lutf
Objectives. To investigate the incidence of weight gain and hair loss as adverse effects of anti-TNF therapy in rheumatic diseases. Methods. Patients using anti-TNF therapy, who are followed in rheumatology clinic, were interviewed using a ...
Immunohistochemical Characteristics of IgG4-Related Tubulointerstitial Nephritis: Detailed Analysis of 20 Japanese Cases [0.03%]
IgG4相关性 tubulo间质性肾炎的免疫组化特征——20例日本患者的详细分析
Mitsuhiro Kawano,Ichiro Mizushima,Yutaka Yamaguchi et al.
Mitsuhiro Kawano et al.
Although tubulointerstitial nephritis with IgG4+ plasma cell (PC) infiltration is a hallmark of IgG4-related kidney disease (IgG4-RKD), only a few studies are available about the minimum number of IgG4+ PC needed for diagnosis along with Ig...
Prevalence of IgG4-Related Disease in Japan Based on Nationwide Survey in 2009 [0.03%]
基于2009年全国调查的日本IgG4相关性疾病患病率
Kazushige Uchida,Atsushi Masamune,Tooru Shimosegawa et al.
Kazushige Uchida et al.
The number of patients with autoimmune pancreatitis who visited hospitals in Japan in 2007 was approximately 2709 (95% confidence interval; range 2540-3040). Because IgG4-related disease is a new clinical entity, there are no data with rega...
Is lifelong knee joint force from work, home, and sport related to knee osteoarthritis? [0.03%]
作业，家务及运动引起的终身膝关节力作用与骨关节炎的关系吗？
Charles R Ratzlaff,Mieke Koehoorn,Jolanda Cibere et al.
Charles R Ratzlaff et al.
Purpose. To investigate the association of cumulative lifetime knee joint force on the risk of self-reported medically-diagnosed knee osteoarthritis (OA). Methods. Exposure data on lifetime physical activity type (occupational, household, s...
Markers of treatment response to methotrexate in rheumatoid arthritis: where do we stand? [0.03%]
甲氨蝶呤治疗类风湿关节炎疗效预测标志物研究进展及展望
Karina I Halilova,Elizabeth E Brown,Sarah L Morgan et al.
Karina I Halilova et al.
Methotrexate (MTX) is the most commonly used disease-modifying antirheumatic drug (DMARD) for the treatment of rheumatoid arthritis (RA). However, despite its efficacy and affordability, additional DMARDs or biologic agents are often requir...
Daniel S Smyk,Eirini I Rigopoulou,Andreas L Koutsoumpas et al.
Daniel S Smyk et al.
Autoimmune pancreatitis (AIP) was first used to describe cases of pancreatitis with narrowing of the pancreatic duct, enlargement of the pancreas, hyper-γ-globulinaemia, and antinuclear antibody (ANA) positivity serologically. The main dif...
MR Imaging of Intra- and Periarticular Cyst-Like Lesions of the Knee Joint in Workers with Occupational Kneeling [0.03%]
长期跪位作业工人的膝关节滑膜囊肿的磁共振表现研究
Søren Rytter,Lilli Kirkeskov Jensen,Jens Peter Bonde et al.
Søren Rytter et al.
Objective. To determine the risk of intra- and periarticular cyst-like lesions of the knee joint in occupational kneeling. Methods. Magnetic resonance imaging of both knees (n = 282) was conducted in 92 male floor layers and 49 male graphic...
Yasuharu Sato,Tadashi Yoshino
Yasuharu Sato
Lymphadenopathy is frequently observed in patients with immunoglobulin G4-related disease (IgG4-RD) and sometimes appears as the first manifestation of the disease. The diagnosis of IgG4-related lymphadenopathy is complicated owing to a gre...
IgG4-Related Fibrotic Diseases from an Immunological Perspective: Regulators out of Control? [0.03%]
从免疫学角度谈IgG4相关纤维化疾病：脱缰的调节性免疫细胞？
Laura C Lighaam,Rob C Aalberse,Theo Rispens
Laura C Lighaam
Patients with autoimmune pancreatitis have a striking polyclonal elevation of total IgG4 in serum. This observation has been confirmed and extended to other fibrotic conditions (that are therefore called IgG4-related disease) but as yet rem...
Autoantigen TRIM21/Ro52 as a Possible Target for Treatment of Systemic Lupus Erythematosus [0.03%]
自身抗原TRIM21/Ro52可能是治疗系统性红斑狼疮的靶点
Ryusuke Yoshimi,Yoshiaki Ishigatsubo,Keiko Ozato
Ryusuke Yoshimi
Systemic lupus erythematosus (SLE) is a chronic, systemic, and autoimmune disease, whose etiology is still unknown. Although there has been progress in the treatment of SLE through the use of glucocorticoid and immunosuppressive drugs, thes...