A Human Head and Neck Squamous Cell Carcinoma Cell Line with Acquired cis-Diamminedichloroplatinum-Resistance Shows Remarkable Upregulation of BRCA1 and Hypersensitivity to Taxane [0.03%]
一个获得顺铂耐药的人类头颈鳞状细胞癌细胞系显示BRCA1表达显著上调和对紫杉烷类药物的高敏性
Yuriko Saiki,Takenori Ogawa,Kiyoto Shiga et al.
Yuriko Saiki et al.
Recently, an inverse relationship between resistance to platinum-based chemotherapeutic agents and taxanes has been implicated in breast and ovarian cancers, and a possible pivotal role for BRCA1 has also been suggested. Because cis-diammin...
The lyon clinical olfactory test: validation and measurement of hyposmia and anosmia in healthy and diseased populations [0.03%]
里昂临床嗅觉检查法:健康人群和患者中嗅觉减退和嗅觉丧失的测定与验证
Catherine Rouby,Thierry Thomas-Danguin,Michel Vigouroux et al.
Catherine Rouby et al.
The LCOT is a self-administered test designed to assess olfactory deficits. Altogether, 525 subjects contributed to the validation. Elderly participants were well represented in this sample. In a validation study (study 1), 407 healthy and ...
Height of right and left ethmoid roofs: aspects of laterality in 644 patients [0.03%]
644例患者的右、左蝶筛顶高度的侧别差异性分析
Michael Reiß,Gilfe Reiß
Michael Reiß
Objective. The goal of the study was to determine the asymmetric distribution of the height of the ethmoid roof (fovea ethmoidalis). Method. We retrospectively reviewed 644 coronal sinus computer tomography (CT) scans. The height of the eth...
The cost of cochlear implantation: a review of methodological considerations [0.03%]
人工耳蜗植入的费用:研究方法考量综述
Costa Nadège,Garnault Valérie,Ferlicoq Laura et al.
Costa Nadège et al.
Objectives. Cost studies can provide useful guidance, so long as they adhere to accepted methodology. Cochlear implants (CIs) are electronic devices introduced surgically into the inner ear. It is a relevant example to review cost study ana...
André L L Sampaio,Mercêdes F S Araújo,Carlos A C P Oliveira
André L L Sampaio
Numerous changes continue to occur in cochlear implant candidacy. In general, these have been accompanied by concomitant and satisfactory changes in surgical techniques. Together, this has advanced the utility and safety of cochlear implant...
Stavros Korres,Linda Luxon,Paolo Vannucchi et al.
Stavros Korres et al.
The effect of pulling out cochlear implant electrodes on inner ear microstructures: a temporal bone study [0.03%]
人工耳蜗电极拔出对内耳微结构影响的颞骨研究
Ingo Todt,Rainer O Seidl,Arne Ernst
Ingo Todt
The exchange of an cochlear implant or the re-positioning of an electrode have become more frequently required than a decade ago. The consequences of such procedures at a microstructural level within the cochlea are not known. It was the ai...
Reduced formation of oxidative stress biomarkers and migration of mononuclear phagocytes in the cochleae of chinchilla after antioxidant treatment in acute acoustic trauma [0.03%]
抗氧化剂治疗后急性格林瓦伦损伤耳蜗氧化应激生物标志物的形成减少及单核吞噬细胞迁移减少:耳科实验模型中的作用机制研究
Xiaoping Du,Chul-Hee Choi,Kejian Chen et al.
Xiaoping Du et al.
Objective. Inhibition of inflammation and free radical formation in the cochlea may be involved in antioxidant treatment in acute acoustic trauma. Procedure. Chinchilla were exposed to 105 dB sound pressure level octave band noise for 6 hou...
Communication, psychosocial, and educational outcomes of children with cochlear implants and challenges remaining for professionals and parents [0.03%]
人工耳蜗植入儿童的交流、心理社会及教育预后效果和发展过程中专业人士与家长所面临的挑战
Renée Punch,Merv B Hyde
Renée Punch
This paper provides an overview and a synthesis of the findings of a large, multifaceted study investigating outcomes from paediatric cochlear implantation. The study included children implanted at several Australian implant clinics and att...
Inner ear disease and benign paroxysmal positional vertigo: a critical review of incidence, clinical characteristics, and management [0.03%]
内耳疾病与良性阵发性位置性眩晕:发病率、临床特征和治疗方法的批判性回顾
M Riga,A Bibas,J Xenellis et al.
M Riga et al.
Background. This study is a review of the incidence, clinical characteristics, and management of secondary BPPV. The different subtypes of secondary BPPV are compared to each other, as well as idiopathic BPPV. Furthermore, the study highlig...