Sheetal Verma,Tamisha Vaughan,Kevin D Bunting
Sheetal Verma
The Grb-2 associated binder (Gab) family of scaffolding/adaptor/docking proteins is a group of three molecules with significant roles in cytokine receptor signaling. Gabs possess structural motifs for phosphorylation-dependent receptor recr...
HIV-Associated Burkitt Lymphoma: Good Efficacy and Tolerance of Intensive Chemotherapy Including CODOX-M/IVAC with or without Rituximab in the HAART Era [0.03%]
艾滋病相关的伯基特淋巴瘤：包括CODOX-M/IVAC（含或不含利妥昔单抗）强化疗在高效抗逆转录病毒治疗时代疗效和耐受性良好
J A Rodrigo,L K Hicks,M C Cheung et al.
J A Rodrigo et al.
Background. The outcome of HIV-associated non-Hodgkin lymphoma (NHL) has improved substantially in the highly active antiretroviral therapy (HAART) era. However, HIV-Burkitt lymphoma (BL), which accounts for up to 20% of HIV-NHL, has poor o...
Maura Rossi,Maria Antonella Laginestra,Anna Gazzola et al.
Maura Rossi et al.
In the last years, several studies of molecular profiling of aggressive lymphomas were performed. In particular, it was shown that DLBCL can be distinguished in two different entities according to GEP. Specifically, ABC and GCB subtypes wer...
Pathogenetic, Clinical, and Prognostic Features of Adult t(4;11)(q21;q23)/MLL-AF4 Positive B-Cell Acute Lymphoblastic Leukemia [0.03%]
成人t(4;11)(q21;q23)/MLL-AF4阳性B细胞急性淋巴细胞白血病的病因、临床及预后特征分析
F Marchesi,K Girardi,G Avvisati
F Marchesi
Translocation t(4;11)(q21;q23) leading to formation of MLL-AF4 fusion gene is found in about 10% of newly diagnosed B-cell acute lymphoblastic leukemia (ALL) in adult patients. Patients expressing this chromosomal aberration present typical...
Long-Term Outcome after Autologous Stem Cell Transplantation with Adequate Peripheral Blood Stem Cell Mobilization Using Plerixafor and G-CSF in Poor Mobilizer Lymphoma and Myeloma Patients [0.03%]
plerixafor和G-CSF充分动员外周血干细胞的自体造血干细胞移植治疗动员不良淋巴瘤及多发性骨髓瘤患者的长期疗效分析
Jan S Moreb,Donya Salmasinia,Jack Hsu et al.
Jan S Moreb et al.
Poor peripheral blood stem cell (PBSC) mobilization predicts worse outcome for myeloma and lymphoma patients post autologous stem cell transplant (ASCT). We hypothesize that PBSC harvest using plerixafor and G-CSF in poor mobilizers may imp...
Clinical Application of Mesenchymal Stem Cells in the Treatment and Prevention of Graft-versus-Host Disease [0.03%]
间充质干细胞在治疗和预防移植物抗宿主病中的临床应用
Yi Lin,William J Hogan
Yi Lin
Mesenchymal stem cells (MSCs) represent a heterogeneous population of stromal cells with pluripotent mesenchymal differentiation potential. They have been found to have immunosuppressive properties and the ability to modulate angiogenesis a...
Xiaoling Liu,Himalee Sabnis,Kevin D Bunting et al.
Xiaoling Liu et al.
Significant advances in our understanding of the genetic defects and the pathogenesis of juvenile myelomonocytic leukemia (JMML) have been achieved in the last several years. The information gathered tremendously helps us in designing molec...
Expression of thymidine phosphorylase in lymph nodes involved with mycosis fungoides and sézary syndrome [0.03%]
霉菌样真菌病和塞扎里综合征淋巴结中胸苷磷酸化酶的表达
Xingcao Nie,Rekha Bhat,Essel Dulaimi Al-Saleem et al.
Xingcao Nie et al.
Thymidine phosphorylase may be overexpressed in both neoplastic cells and tumor stromal cells in a variety of malignancies. Our study explores thymidine phosphorylase expression in lymph nodes (LNs) from patients with mycosis fungoides (MF)...
Heme Oxygenase-1: A Critical Link between Iron Metabolism, Erythropoiesis, and Development [0.03%]
血红素氧合酶-1：铁代谢、红细胞生成和发育之间的关键联系
Stuart T Fraser,Robyn G Midwinter,Birgit S Berger et al.
Stuart T Fraser et al.
The first mature cells to arise in the developing mammalian embryo belong to the erythroid lineage. This highlights the immediacy of the need for red blood cells during embryogenesis and for survival. Linked with this pressure is the necess...
Pelle G Lindqvist,Margareta Hellgren
Pelle G Lindqvist
Obstetric thromboprophylaxis is difficult. Since 10 years Swedish obstetricians have used a combined risk estimation model and recommendations concerning to whom, at what dose, when, and for how long thromboprophylaxis is to be administrate...