Salemiz Sandoval,Martina Pigazzi,Kathleen M Sakamoto
Salemiz Sandoval
The cAMP response element-binding protein (CREB) is a nuclear transcription factor downstream of cell surface receptors and mitogens that is critical for normal and neoplastic hematopoiesis. Previous work from our laboratory demonstrated th...
Adele Bolognese,Anna Esposito,Michele Manfra et al.
Adele Bolognese et al.
The (R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl-boronic acid, bortezomib (BTZ), which binds the 20S proteasome subunit and causes a large inhibition of its activity, is a peptidomimetic boronic drug mainly used ...
Hairy cell leukemia and bladder cancer in a patient: relation with dye exposure and review of the literaure [0.03%]
与染料暴露有关的血管免疫母T细胞淋巴瘤并发毛细胞白血病及文献复习
Semra Paydas
Semra Paydas
Chemical exposure is important in the etiology of some cancers. Dye or solvent exposures are important both in bladder cancer (BC) and hairy cell leukemia (HCL). Here a case with BC and HCL has been presented and literature has been reviewe...
Case Reports
Advances in hematology. 2009:2009:812960. DOI:10.1155/2009/812960 2009
Taro Ishigaki,Kazuhiro Sudo,Takashi Hiroyama et al.
Taro Ishigaki et al.
We previously reported that long-lasting in vitro hematopoiesis could be achieved using the cells differentiated from primate embryonic stem (ES) cells. Thus, we speculated that hematopoietic stem cells differentiated from ES cells could su...
Vitamin e and N-acetylcysteine as antioxidant adjuvant therapy in children with acute lymphoblastic leukemia [0.03%]
维生素E和N-乙酰半胱氨酸作为儿童急性淋巴细胞白血病抗氧化辅助治疗的影响
Youssef Al-Tonbary,Mohammad Al-Haggar,Rasha El-Ashry et al.
Youssef Al-Tonbary et al.
Although cancer therapies have experienced great success nowadays, yet the associated toxic response and free radicals formation have resulted in significant number of treatment-induced deaths rather than disease-induced fatalities. Complic...
Aspirin resistance [0.03%]
阿司匹林抵抗性
Khaled Mansour,Ali T Taher,Khaled M Musallam et al.
Khaled Mansour et al.
The development of adverse cardiovascular events despite aspirin use has established an interest in a possible resistance to the drug. Several definitions have been set and various laboratory testing modalities are available. This has led t...
Comorbidities of idiopathic thrombocytopenic purpura: a population-based study [0.03%]
特发性血小板减少性紫癜伴发疾病的流行病学研究
M A Feudjo-Tepie,G Le Roux,K J Beach et al.
M A Feudjo-Tepie et al.
A person experiencing more than one medical condition may have ambiguous clinical presentation. ITP is a serious autoimmune disease with little epidemiological evidence on its burden, risk factors, and comorbidities. Using the United Kingdo...
Prevention of cardiomyopathy in transfusion-dependent homozygous thalassaemia today and the role of cardiac magnetic resonance imaging [0.03%]
当今输血依赖性β-地贫的心肌病预防及心脏磁共振的作用
Athanassios Aessopos,Vasilios Berdoukas,Maria Tsironi
Athanassios Aessopos
Transfusion and iron chelation therapy revolutionised survival and reduced morbidity in patients with transfusion-dependent beta thalassaemia major. Despite these improvements, cardiac disease remained the most common cause of death in thos...
HFE-Related Hemochromatosis: The Haptoglobin 2-2 Type Has a Significant but Limited Influence on Phenotypic Expression of the Predominant p.C282Y Homozygous Genotype [0.03%]
血色病相关性造血干细胞疾病：具有重要但有限的影响 Hp 2-2 型表型表达主要同合子基因型p. C282Y
Gérald Le Gac,Chandran Ka,Isabelle Gourlaouen et al.
Gérald Le Gac et al.
Phenotypic expression of the common p.C282Y/p.C282Y HFE-related hemochromatosis genotype is heterogeneous and depends on a complex interplay of genetic and non-genetic factors. Haptoglobin has a crucial role in free hemoglobin iron recovery...
Marnelli A Bautista,Walter D Y Quan,Jun Wang
Marnelli A Bautista
The activity of the anti-CD20 monoclonal antibody, rituximab in B-cell non-Hodgkin's lymphoma, with relatively minimal toxicity has been well established. Adverse effects such as low-grade fever, urticaria, bronchospasm, sporadic tachycardi...
Case Reports
Advances in hematology. 2009:2009:272495. DOI:10.1155/2009/272495 2009