Hong Ye,Tracey A Rouault
Hong Ye
Erythropoiesis in animals is a synchronized process of erythroid cell differentiation that depends on successful acquisition of iron. Heme synthesis depends on iron through its dependence on iron sulfur (Fe-S) cluster biogenesis. Here, we r...
Stefano Rivella,Elizabeta Nemeth,Jeffery Lynn Miller
Stefano Rivella
The Effect of Imatinib Mesylate for Newly Diagnosed Philadelphia Chromosome-Positive, Chronic-Phase Myeloid Leukemia in Sub-Saharan African Patients: The Experience of Côte d'Ivoire [0.03%]
伊马替尼治疗撒哈拉以南非洲国家慢性期费城染色体阳性白血病患者的疗效：科特迪瓦的经验分析
K G Koffi,D C Nanho,E N&#x;dathz et al.
K G Koffi et al.
Imatinib mesylate, showed encouraging activity in chronic myelogenous leukemia. However, there are few data regarding his efficacy and response monitoring in Sub-Saharan African patients. Our objective was to assess response to imatinib mes...
Luciano Cianetti,Marco Gabbianelli,Nadia Maria Sposi
Luciano Cianetti
In recent years there have been major advances in our knowledge of the regulation of iron metabolism that have had implications for understanding the pathophysiology of some human disorders like beta-thalassemia and other iron overload dise...
Echocardiographic Assessment of Left Ventricular Function in Type 1 Gaucher's Disease [0.03%]
第一型Gaucher病患者左心室功能的超声心动图评估
Mirta Kozelj,Samo Zver,Vesna Zadnik
Mirta Kozelj
There is predominate opinion among physicians managing type 1 Gauchers' disease (GD) that cardiac involvement is not an issue in these patients. In order to follow this hypothesis, we prospectively investigated 15 adult imiglucerase-treated...
Asn and asn: critical residues for in vitro biological activity of reteplase [0.03%]
纤溶酶重组替普 Sele(Asn47和Ser158)对体外生物学活性的影响
Naganath Mandi,Kalyana R Sundaram,Sunil K Tandra et al.
Naganath Mandi et al.
Reteplase (rPA) is a thrombolytic agent used for the treatment of acute myocardial infarction. We studied the expression of rPA and its selected asparagine mutants after integration into the Pichia genome. Though methanol induction of the n...
Life-threatening adenovirus infections in the setting of the immunocompromised allogeneic stem cell transplant patients [0.03%]
异基因干细胞移植患者的免疫抑制状态下腺病毒致死性感染
Cedar J Fowler,Jennifer Dunlap,Darcy Troyer et al.
Cedar J Fowler et al.
A single institution case series of adenovirus infections after allogeneic hematopoietic stem cell transplantation is presented to highlight the consideration for adenovirus infections as an etiology in patients with rapid hepatic or other ...
Case Reports
Advances in hematology. 2010:2010:601548. DOI:10.1155/2010/601548 2010
Emanuela Messa,Daniela Cilloni,Giuseppe Saglio
Emanuela Messa
Myelodysplastic syndromes (MDS) are a heterogeneous disorder of the hematopoietic stem cells, frequently characterized by anemia and transfusion dependency. In low-risk patients, transfusion dependency can be long lasting, leading to iron o...
State-of-the-Art Management of Complications of Myeloma and Its Treatment [0.03%]
2019年多发性骨髓瘤及其治疗并发症的管理最新进展
Monique A Hartley-Brown,Daniel M Sullivan,Rachid Baz
Monique A Hartley-Brown
Multiple myeloma is an incurable disease, although patient survival has increased with the availability of novel agents. Both multiple myeloma and its therapies often affect the renal, immune, skeletal, hematologic, and nervous systems. The...
Huihui Li,Yelena Z Ginzburg
Huihui Li
Iron metabolism and erythropoiesis are inextricably linked. The majority of iron extracted from circulation daily is used for hemoglobin synthesis. In the last 15 years, major advances have been made in understanding the pathways regulating...