The Role of Allogeneic Stem Cell Transplantation in Relapsed/Refractory Hodgkin's Lymphoma Patients [0.03%]
自体干细胞移植失败后的霍奇金淋巴瘤患者同种异体干细胞移植的作用
Evgeny Klyuchnikov,Ulrike Bacher,Nicolaus Kröger et al.
Evgeny Klyuchnikov et al.
Despite the favorable prognosis of most patients with Hodgkin's Lymphoma (HL), 15-20% of patients remain refractory to chemoradiotherapy, and 20-40% experience relapses following autologous stem cell transplantation (SCT) being used as salv...
Kheng-Wei Yeoh,N George Mikhaeel
Kheng-Wei Yeoh
Hodgkin's Lymphoma was incurable until the advent of effective therapeutic radiation around the first half of the 20th century. As survival rates improved, the long-term toxicities from radiotherapy began to emerge. This together with the a...
The effects of forodesine in murine and human multiple myeloma cells [0.03%]
Forodesine对小鼠和人类多发性骨髓瘤细胞的影响
Liesbeth Bieghs,Jo Caers,Elke De Bruyne et al.
Liesbeth Bieghs et al.
Multiple myeloma (MM) is the second most commonly diagnosed hematological malignancy, characterized by a monoclonal proliferation of malignant cells in the bone marrow. Despite recent advances in treatment strategies, MM remains incurable a...
S Montes-Moreno
S Montes-Moreno
Thomas Hodgkin's and Samuel Wilks first recognized Hodgkin disease in the first half of the 19th century. Initially described as lymphogranulomatosis, it was later recognized to be a lymphoid neoplasm derived from B cells and was classified...
Sean Grimm,Marc Chamberlain
Sean Grimm
Hodgkin's lymphoma is a hematolymphoid neoplasm, primarily of B cell lineage, that has unique histologic, immunophenotypic, and clinical features. Neurologic complications of Hodgkin's Lymphoma can be separated into those that result direct...
T-Cell Traffic Jam in Hodgkin's Lymphoma: Pathogenetic and Therapeutic Implications [0.03%]
霍奇金淋巴瘤中T细胞浸润障碍的病理生理及治疗意义探讨
Claudio Fozza,Maurizio Longinotti
Claudio Fozza
In hematologic malignancies, the microenvironment is often characterized by nonneoplastic cells with peculiar phenotypic and functional features. This is particularly true in Hodgkin's lymphoma (HL), in which T lymphocytes surrounding Hodgk...
Current Genetic Epidemiology of β-Thalassemias and Structural Hemoglobin Variants in the Lazio Region (Central Italy) Following Recent Migration Movements [0.03%]
近期移民后拉齐奥地区(意大利中部)β-地中海贫血和结构血红蛋白变异的当前遗传流行病学
Antonio Amato,Maria Pia Cappabianca,Alessia Colosimo et al.
Antonio Amato et al.
The aim of this study was to describe the changing pattern of mutational spectrum of β-thalassemia (β-thal) in the Lazio region (Central Italy), as consequence of recent demographic variations. From 1994 until present, 256 immigrant subje...
Michele Spina,Antonino Carbone,Annunziata Gloghini et al.
Michele Spina et al.
Hodgkin lymphoma (HL) represents one of the most common non-AIDS-defining cancers with an increasing incidence overtime. Clinically, patients present advanced stages of disease with extranodal involvement in the majority of cases. In the la...
Flow cytometry and polymerase chain reaction-based analyses of minimal residual disease in chronic lymphocytic leukemia [0.03%]
流式细胞仪和聚合酶链反应对慢性淋巴细胞性白血病微量残存病的分析
Sabrina Uhrmacher,Felix Erdfelder,Karl-Anton Kreuzer
Sabrina Uhrmacher
New therapeutic strategies developed recently for chronic lymphocytic leukemia (CLL) have led to remarkable treatment response rates and complete hematological remissions. This means highly sensitive and specific techniques are increasingly...
Vinod Pullarkat
Vinod Pullarkat
Recipients of hematopoietic stem cell transplantation (HSCT) frequently have iron overload resulting from chronic transfusion therapy for anemia. In some cases, for example, in patients with myelodysplastic syndromes and thalassemia, this c...