David E Kang,Michael C Lee,Jaydip Das Gupta et al.
David E Kang et al.
Xenotropic murine leukemia virus-related virus (XMRV) was first reported in 2006 in a study of human prostate cancer patients with genetic variants of the antiviral enzyme, RNase L. Subsequent investigations in North America, Europe, Asia, ...
Alan Rein
Alan Rein
Murine leukemia viruses (MLVs) are among the simplest retroviruses. Prototypical gammaretroviruses encode only the three polyproteins that will be used in the assembly of progeny virus particles. These are the Gag polyprotein, which is the ...
Michael Veit,Bastian Thaa
Michael Veit
Assembly and budding of influenza virus proceeds in the viral budozone, a domain in the plasma membrane with characteristics of cholesterol/sphingolipid-rich membrane rafts. The viral transmembrane glycoproteins hemagglutinin (HA) and neura...
Testing strategies for detection of xenotropic murine leukemia virus-related virus infection [0.03%]
检测XMRV感染的检验策略的评估
Shixing Tang,Indira K Hewlett
Shixing Tang
Xenotropic murine leukemia virus-related virus (XMRV) is a newly identified gamma retrovirus and may be associated with prostate cancer- (PC) and chronic fatigue syndrome (CFS). Since its identification in 2006 and detection of polytropic m...
Nucleic Acid, Antibody, and Virus Culture Methods to Detect Xenotropic MLV-Related Virus in Human Blood Samples [0.03%]
人血样本中检测XMRV病毒的核糖核酸、抗体和病毒培养方法
M F Kearney,K Lee,R K Bagni et al.
M F Kearney et al.
The MLV-related retrovirus, XMRV, was recently identified and reported to be associated with both prostate cancer and chronic fatigue syndrome. At the National Cancer Institute-Frederick, MD (NCI-Frederick), we developed highly sensitive me...
Anyou Wang,Li Ren,Hong Li
Anyou Wang
Virus entry is a multistep process that triggers various cellular pathways that interconnect into a complex network; yet the molecular complexity of this network remains largely elusive. Here, by employing systems biology approaches, we rev...
Does Cytomegalovirus Develop Resistance following Antiviral Prophylaxis and Treatment in Renal Transplant Patients in Kuwait? [0.03%]
移植肾脏受者抗病毒预防和治疗后巨细胞病毒是否产生耐药？
Nada Madi,Widad Al-Nakib,Alexander Pacsa
Nada Madi
The resistance of cytomegalovirus (CMV) to ganciclovir or valganciclovir is a factor in therapeutic failure and disease progression. CMV strains resistant to ganciclovir or valganciclovir have been associated with specific mutations in the ...
Replication of alphaviruses: a review on the entry process of alphaviruses into cells [0.03%]
甲病毒的复制：甲病毒进入细胞过程的综述
Jason Yat-Sing Leung,Mary Mah-Lee Ng,Justin Jang Hann Chu
Jason Yat-Sing Leung
Alphaviruses are small, enveloped viruses, ~70 nm in diameter, containing a single-stranded, positive-sense, RNA genome. Viruses belonging to this genus are predominantly arthropod-borne viruses, known to cause disease in humans. Their pote...
Arenavirus budding [0.03%]
Arenavirus病毒芽生现象
Shuzo Urata,Juan Carlos de la Torre
Shuzo Urata
Several arenaviruses cause hemorrhagic fever disease in humans and pose a significant public health concern in their endemic regions. On the other hand, the prototypic arenavirus LCMV is a superb workhorse for the investigation of virus-hos...
Artificial 64-Residue HIV-1 Enhancer-Binding Peptide Is a Potent Inhibitor of Viral Replication in HIV-1-Infected Cells [0.03%]
人工合成的六十四氨基酸残基HIV-1增强子结合肽可有效抑制HIV-1感染细胞中的病毒复制
Mouhssin Oufir,Leslie R Bisset,Stefan R K Hoffmann et al.
Mouhssin Oufir et al.
An artificial HIV-1 enhancer-binding peptide was extended by nine consecutive arginine residues at the C-terminus and by the nuclear localization signal of SV40 large T antigen at the N-terminus. The resulting synthetic 64-residue peptide w...