Maxine Bauzon,Terry W Hermiston
Maxine Bauzon
Attempts at developing oncolytic viruses have been primarily based on rational design. However, this approach has been met with limited success. An alternative approach employs directed evolution as a means of producing highly selective and...
Swarna Bais,Eric Bartee,Masmudur M Rahman et al.
Swarna Bais et al.
Hematological malignancies such as leukemias, lymphomas, multiple myeloma (MM), and the myelodysplastic syndromes (MDSs) primarily affect adults and are difficult to treat. For high-risk disease, hematopoietic stem cell transplant (HCT) can...
Naturally Occurring Polymorphisms of the Mouse Gammaretrovirus Receptors CAT-1 and XPR1 Alter Virus Tropism and Pathogenicity [0.03%]
小鼠γ逆转录病毒受体CAT-1和XPR1的天然多态性改变病毒嗜性和致病性
Christine A Kozak
Christine A Kozak
Gammaretroviruses of several different host range subgroups have been isolated from laboratory mice. The ecotropic viruses infect mouse cells and rely on the host CAT-1 receptor. The xenotropic/polytropic viruses, and the related human-deri...
Prachi Sharma,Kenneth A Rogers,Suganthi Suppiah et al.
Prachi Sharma et al.
Although XMRV dissemination in humans is a matter of debate, the prostate of select patients seem to harbor XMRV, which raises questions about its potential route of transmission. We established a model of infection in rhesus macaques inocu...
Ronald N Harty,Anthony P Schmitt,Fadila Bouamr et al.
Ronald N Harty et al.
Endogenous Murine Leukemia Viruses: Relationship to XMRV and Related Sequences Detected in Human DNA Samples [0.03%]
内源性小鼠白血病病毒与XMRV及在人类DNA样品中检测到的相关序列的关系
Oya Cingöz,John M Coffin
Oya Cingöz
Xenotropic-murine-leukemia-virus-related virus (XMRV) was the first gammaretrovirus to be reported in humans. The sequence similarity between XMRV and murine leukemia viruses (MLVs) was consistent with an origin of XMRV from one or more MLV...
Perspective: emerging challenges in the treatment of influenza and parainfluenza in transplant patients [0.03%]
移植患者的流感和副流感治疗面临的挑战透视观点文章
Ronald B Moss,Roy T Steigbigel,Rebecca L Sanders et al.
Ronald B Moss et al.
Influenza, respiratory synctial virus, and parainfluenza are common respiratory infections in immunocompromised transplant recipients, causing significant morbidity and mortality in this patient population. This paper focuses on influenza a...
Failure to Detect XMRV-Specific Antibodies in the Plasma of CFS Patients Using Highly Sensitive Chemiluminescence Immunoassays [0.03%]
采用高灵敏的化学发光免疫法未能在慢性疲劳综合征患者的血浆中检测到XMRV特异性抗体
Brendan Oakes,Xiaoxing Qiu,Susan Levine et al.
Brendan Oakes et al.
In 2009, Lombardi et al. reported their startling finding that the gammaretrovirus xenotropic murine leukemia virus-related retrovirus (XMRV) is present in 67% of blood samples of patients suffering from chronic fatigue syndrome (CFS), as o...
MoMuLV-ts-1: A Unique Mouse Model of Retrovirus-Induced Lymphoma Transmitted by Breast Milk [0.03%]
乳汁传播的逆转录病毒诱发的小鼠淋巴瘤模型MoMuLV-ts-1号
J Chakraborty,H Okonta,H Bagalb et al.
J Chakraborty et al.
Our laboratory has developed a murine model of lymphoma via breast milk transmission of MoMuLV-ts-1 (Moloney murine leukemia virus-temperature sensitive mutant-1). Uninfected offspring suckled from infected surrogate mothers become infected...
Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients [0.03%]
HIV-1淋巴瘤患者中未检出人外源性鼠 leukemia病毒相关病毒
Krista A Delviks-Frankenberry,Chawaree Chaipan,Rachel Bagni et al.
Krista A Delviks-Frankenberry et al.
Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitate...