Application of the new classification on patients with a disorder of sex development in indonesia [0.03%]
印度尼西亚新的性别发育障碍患者分类的应用
A Zulfa Juniarto,Yvonne G van der Zwan,Ardy Santosa et al.
A Zulfa Juniarto et al.
Disorder of sex development (DSD) patients in Indonesia most often do not receive a proper diagnostic evaluation and treatment. This study intended to categorize 88 Indonesian patients in accordance with the new consensus DSD algorithm. Dia...
Androgens and adipose tissue in males: a complex and reciprocal interplay [0.03%]
雄激素和脂肪组织的相互作用：复杂且互惠式
Caterina Mammi,Matilde Calanchini,Antonella Antelmi et al.
Caterina Mammi et al.
Clinical evidence shows that in males obesity is frequently associated with hypogonadism and vice versa; also, low testosterone levels have been considered a "hallmark" of metabolic syndrome in men. These observations indicate that there is...
Genetics of isolated hypogonadotropic hypogonadism: role of GnRH receptor and other genes [0.03%]
孤立性低促性腺激素性性腺功能减退症的遗传学：GnRH受体和其他基因的作用
Karges Beate,Neulen Joseph,de Roux Nicolas et al.
Karges Beate et al.
Hypothalamic gonadotropin releasing hormone (GnRH) is a key player in normal puberty and sexual development and function. Genetic causes of isolated hypogonadotropic hypogonadism (IHH) have been identified during the recent years affecting ...
The involvement of ser1898 of the human L-type calcium channel in evoked secretion [0.03%]
人L型钙通道的Ser1898残基参与激动的分泌作用
Niv Bachnoff,Moshe Cohen-Kutner,Daphne Atlas
Niv Bachnoff
A PKA consensus phosphorylation site S1928 at the α(1)1.2 subunit of the rabbit cardiac L-type channel, Ca(V)1.2, is involved in the regulation of Ca(V)1.2 kinetics and affects catecholamine secretion. This mutation does not alter basal Ca...
Relationship between Serum Concentration of Uric Acid and Insulin Secretion among Adults with Type 2 Diabetes Mellitus [0.03%]
尿酸与2型糖尿病成人胰岛素分泌关系的研究
J A Robles-Cervantes,M G Ramos-Zavala,M González-Ortiz et al.
J A Robles-Cervantes et al.
To determine the relationship between serum concentrations of uric acid and insulin secretion with hyperglycaemic clamp technique among adults with type 2 diabetes mellitus (DM2) without hyperuricemia, we carried out a cross-sectional study...
Clinical and Laboratorial Features That May Differentiate 46,XY DSD due to Partial Androgen Insensitivity and 5α-Reductase Type 2 Deficiency [0.03%]
部分雄激素不敏感综合征和5α-还原酶2缺陷症所致46，XY DSD的临床及实验室鉴别特征
Nélio Neves Veiga-Junior,Pedro Augusto Rodrigues Medaets,Reginaldo José Petroli et al.
Nélio Neves Veiga-Junior et al.
The aim of this study was to search for clinical and laboratorial data in 46,XY patients with ambiguous genitalia (AG) and normal testosterone (T) synthesis that could help to distinguish partial androgen insensitivity syndrome (PAIS) from ...
Liver Glucokinase(A456V) Induces Potent Hypoglycemia without Dyslipidemia through a Paradoxical Induction of the Catalytic Subunit of Glucose-6-Phosphatase [0.03%]
肝葡萄糖激酶（A456V）通过诱导葡萄糖-6-磷酸酶催化亚基的表达来引起强力低血糖且不产生血脂异常
Anna Vidal-Alabró,Alícia G Gómez-Valadés,Andrés Méndez-Lucas et al.
Anna Vidal-Alabró et al.
Recent reports point out the importance of the complex GK-GKRP in controlling glucose and lipid homeostasis. Several GK mutations affect GKRP binding, resulting in permanent activation of the enzyme. We hypothesize that hepatic overexpressi...
Long-term followup of adolescent and young adult females with hypergonadotropic hypogonadism [0.03%]
青春期内分泌性腺功能低下的长期随访
Pantelis Tsimaris,Nikolaos Vrachnis,Zoe Iliodromiti et al.
Pantelis Tsimaris et al.
The condition characterized by elevated gonadotrophins (gonadotropins elevated into the menopausal range), low sex steroids, and menstrual disorders was previously termed Premature Ovarian Failure (POF). However, over the last two years an ...
Does varicocelectomy improve gonadal function in men with hypogonadism and infertility? Analysis of a prospective study [0.03%]
附睾切除术可改善低促性腺激素性性腺功能减退症和不育男性患者的生精功能：一项前瞻性研究分析
Vasan Sathya Srini,Srinivas Belur Veerachari
Vasan Sathya Srini
Varicocele in infertile males is associated with Leydig cell dysfunction and hypogonadism. The effect of varicocelectomy on serum testosterone level is not yet established. We analysed 200 heterosexual infertile men diagnosed to have clinic...
Androgen Receptor Regulates Transcription of the ZEB1 Transcription Factor [0.03%]
雄激素受体调节ZEB1转录因子的转录
Bynthia M Anose,Michel M Sanders
Bynthia M Anose
The zinc finger E-box binding protein 1 (ZEB1) transcription factor belongs to a two-member family of zinc-finger homeodomain proteins involved in physiological and pathological events mostly relating to cell migration and epithelial to mes...