Nikolaos Vrachnis,Areti Augoulea,Zoe Iliodromiti et al.
Nikolaos Vrachnis et al.
The prevalence of gestational diabetes mellitus (GDM) in the developed world has increased at an alarming rate over the last few decades. GDM has been shown to be associated with postpartum diabetes, insulin resistance, hypertension, and dy...
Surgery and radiosurgery for acromegaly: a review of indications, operative techniques, outcomes, and complications [0.03%]
肢端肥大症的手术和放射外科治疗:指征、手术技术、疗效及并发症综述
Yvette Marquez,Alexander Tuchman,Gabriel Zada
Yvette Marquez
Among multimodality treatments for acromegaly, the goals of surgical intervention are to balance maximal tumor resection while preserving normal pituitary function and maintaining patient safety. The resection of growth hormone-(GH-) secret...
A cell model for conditional profiling of androgen-receptor-interacting proteins [0.03%]
一种用于雄激素受体相互作用蛋白条件性分析的细胞模型
K A Mooslehner,J D Davies,I A Hughes
K A Mooslehner
Partial androgen insensitivity syndrome (PAIS) is associated with impaired male genital development and can be transmitted through mutations in the androgen receptor (AR). The aim of this study is to develop a cell model suitable for studyi...
Alberto Franzin,Giorgio Spatola,Marco Losa et al.
Alberto Franzin et al.
Objective. Single-session radiosurgery with Gamma Knife (GK) may be a potential adjuvant treatment in acromegaly. We analyzed the safety and efficacy of GK in patients who had previously received maximal surgical debulking at our hospital. ...
Morphological and histopathological changes in orofacial structures of experimentally developed acromegaly-like rats: an overview [0.03%]
实验性肢端肥大症样模型大鼠口腔颌面部组织形态及病理变化概述
Masahiro Iikubo,Ikuho Kojima,Maya Sakamoto et al.
Masahiro Iikubo et al.
Tongue enlargement and mandibular prognathism are clinically recognized in almost all patients with acromegaly. An acromegaly-like rat model recently developed by exogenous administration of insulin-like growth factor I (IGF-I) was used to ...
A pilot study on dietary approaches in multiethnicity: two methods compared [0.03%]
一种多民族饮食方法研究的试点研究:两种方法对比研究
Romina Valentini,Maria Grazia Dalfrà,Michela Masin et al.
Romina Valentini et al.
Background. Medical nutritional therapy is the most important method for normalizing glucose levels in pregnancy. In this setting, there is a new problem to consider relating to migrants, their personal food preferences, and ethnic, cultura...
Hypogonadism in the aging male diagnosis, potential benefits, and risks of testosterone replacement therapy [0.03%]
老年男性继发性性腺功能减退的诊断、治疗利弊及其风险评估
Prasanth N Surampudi,Christina Wang,Ronald Swerdloff
Prasanth N Surampudi
Hypogonadism in older men is a syndrome characterized by low serum testosterone levels and clinical symptoms often seen in hypogonadal men of younger age. These symptoms include decreased libido, erectile dysfunction, decreased vitality, de...
Synergistic Effect of Hyperglycemia and p27(kip1) Suppression on Adult Mouse Islet Beta Cell Replication [0.03%]
高血糖与p27(Kip1)抑制对成年小鼠胰岛β细胞增殖的协同作用
Szu-Tah Chen,Shin-Huei Fu,Samuel Hsu et al.
Szu-Tah Chen et al.
The complementary role of hyperglycemia and p27(kip1) suppression on islet beta cell regeneration was investigated in a syngeneic mouse model. p27(kip1) gene silencing was performed by infecting islets of C57BL/6 with shRNA lentiviral parti...
Microarchitecture, but not bone mechanical properties, is rescued with growth hormone treatment in a mouse model of growth hormone deficiency [0.03%]
生长激素缺乏小鼠模型中,生长激素治疗可改善微结构但不能改善骨力学性能
Erika Kristensen,Benedikt Hallgrímsson,Douglas W Morck et al.
Erika Kristensen et al.
Growth hormone (GH) deficiency is related to an increased fracture risk although it is not clear if this is due to compromised bone quality or a small bone size. We investigated the relationship between bone macrostructure, microarchitectur...
Role of surrogate markers of atherosclerosis in clinical and subclinical thyroidism [0.03%]
亚临床甲状腺功能异常时动脉粥样硬化替代标志物的作用
Mehmet Gunduz,Ercan Gunduz,Fatih Kircelli et al.
Mehmet Gunduz et al.
Background. Data on the relationship between homocysteine, plasminogen activator inhibitor 1, hs-CRP, fibrinogen, and carotid intima media thickness (CA-IMT) is plenty but contradicting and the majority of the studies investigated this issu...