A pharmacological and toxicological profile of silver as an antimicrobial agent in medical devices [0.03%]
银作为医疗器械中抗菌剂的药理和毒性概述
Alan B G Lansdown
Alan B G Lansdown
Silver is used widely in wound dressings and medical devices as a broad-spectrum antibiotic. Metallic silver and most inorganic silver compounds ionise in moisture, body fluids, and secretions to release biologically active Ag(+). The ion i...
Key Role of Human ABC Transporter ABCG2 in Photodynamic Therapy and Photodynamic Diagnosis [0.03%]
人类ABCG2转运蛋白在光动力治疗和诊断中的关键作用
Toshihisa Ishikawa,Hiroshi Nakagawa,Yuichiro Hagiya et al.
Toshihisa Ishikawa et al.
Accumulating evidence indicates that ATP-binding cassette (ABC) transporter ABCG2 plays a key role in regulating the cellular accumulation of porphyrin derivatives in cancer cells and thereby affects the efficacy of photodynamic therapy and...
Mechanism of Cytosolic Phospholipase A(2) Activation in Ghrelin Protection of Salivary Gland Acinar Cells against Ethanol Cytotoxicity [0.03%]
胃泌素保护唾液腺分泌细胞抵抗乙醇毒性的细胞内磷脂酶A（2）激活机制研究
Bronislaw L Slomiany,Amalia Slomiany
Bronislaw L Slomiany
Ghrelin, a peptide hormone, newly identified in oral mucosal tissues, has emerged recently as an important mediator of the processes of mucosal defense. Here, we report on the mechanism of ghrelin protection against ethanol cytotoxicity in ...
Lectins from the Red Marine Algal Species Bryothamnion seaforthii and Bryothamnion triquetrum as Tools to Differentiate Human Colon Carcinoma Cells [0.03%]
采自红藻Bryothamnion seaforthii和Bryothamnion triquetrum的凝集素用于区分人类结肠癌细胞
Vicente P T Pinto,Henri Debray,Danuta Dus et al.
Vicente P T Pinto et al.
The carbohydrate-binding activity of the algal lectins from the closely related red marine algal species Bryothamnion triquetrum (BTL) and Bryothamnion seaforthii (BSL) was used to differentiate human colon carcinoma cell variants with resp...
Characterization of Prejunctional Muscarinic Receptors: Effects on the Release of VIP and Functional Responses and Receptor Expression in the Ovine Submandibular Gland [0.03%]
绵羊下颌下腺中预突触胆碱能受体的特征：对VIP释放及功能反应和受体表达的影响
Anders T Ryberg,Ondrej Soukup,Gunnar Tobin
Anders T Ryberg
In the in vivo experiments on anaesthetized sheep, it was presently examined whether muscarinic receptor antagonists with diverse selectivity affect the release of VIP in response to electrical stimulation of the parasympathetic chorda tymp...
Monoamines, BDNF, Dehydroepiandrosterone, DHEA-Sulfate, and Childhood Depression-An Animal Model Study [0.03%]
单胺、脑源性神经营养因子、脱氢异雄酮、硫酸脱氢异雄酮和儿童抑郁症-一项动物模型研究
O Malkesman,T Asaf,L Shbiro et al.
O Malkesman et al.
Basal levels of monoamines and DHEA in four main limbic brain regions were measured in prepubertal Wistar Kyoto (WKY) rats (a putative animal model of childhood depression). Basal levels of "Brain-Derived Neurotrophic Factor (BDNF)" were al...
Methods to evaluate the effect of ethanol on the folate analogue: fluorescein methotrexate uptake in human proximal tubular cells [0.03%]
乙醇对荧光素甲氨蝶呤在人近端小管上皮细胞内摄取的影响及其评价方法
Sivakumar Jt Gowder,Kenneth E McMartin
Sivakumar Jt Gowder
Ethanol-induced folate deficiency is due to effects of ethanol on folate metabolism and absorption. We have already shown by using different methods that ethanol interferes with reabsorption of folate from the proximal tubule. In this study...
Testosterone and cholesterol vasodilation of rat aorta involves L-type calcium channel inhibition [0.03%]
雄激素和胆固醇的血管扩张作用涉及钙离子通道的抑制作用：大鼠胸主动脉试验研究
E Alvarez,E Cairrão,M Morgado et al.
E Alvarez et al.
Testosterone has rapid nongenomic vasodilator effects which could be involved in protective cardiovascular actions. Several authors suggested specific mechanisms to explain this effect, but this matter was not clarified yet. We studied the ...