The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation [0.03%]
阿米什云芝通过调节先天性免疫和改善Th1/Th2失衡及炎症发挥抗肿瘤、感染、过敏及炎性疾病的药理作用
Geir Hetland,Egil Johnson,Torstein Lyberg et al.
Geir Hetland et al.
The medicinal mushroom Agaricus blazei Murill from the Brazilian rain forest has been used in traditional medicine and as health food for the prevention of a range of diseases, including infection, allergy, and cancer. Other scientists and ...
Differential Neuroprotection of Selective Estrogen Receptor Agonists against Autonomic Dysfunction and Ischemic Cell Death in Permanent versus Reperfusion Injury [0.03%]
选择性雌激素受体激动剂对永久性和再灌注损伤自主神经保护的差异性研究
Barry J Connell,Tarek M Saleh
Barry J Connell
In the present study, we tested the hypothesis that selective activation of estrogen receptor subtypes (ERα and ERβ) would be neuroprotective following ischemia and/or ischemia-reperfusion, as well as prevent the associated autonomic dysf...
Brian Michael Varisco
Brian Michael Varisco
Acute lung injury (ALI) secondary to sepsis is one of the leading causes of death in sepsis. As such, many pharmacologic and nonpharmacologic strategies have been employed to attenuate its course. Very few of these strategies have proven be...
Pharmacokinetics of p-Aminohippuric Acid and Inulin in Rabbits with Aristolochic Acid Nephropathy [0.03%]
Aristine肾病家兔的对氨基马尿酸和内皮素药动学研究
Chiao-Shih Tseng,Shih-Ming Chen,Shu-Chen Chien et al.
Chiao-Shih Tseng et al.
The characteristics of aristolochic acid nephropathy (AAN) are interstitial fibrosis and atrophy of the proximal tubules, but with no change in glomeruli. To investigate the effects of AA on renal functions and the pharmacokinetics (PKs) of...
Derek S Wheeler,John S Giuliano Jr,Patrick M Lahni et al.
Derek S Wheeler et al.
Albumin appears to have proinflammatory effects in vitro. We hypothesized that albumin would induce a state of tolerance to subsequent administration of lipopolysaccharide (LPS) in vitro and in vivo. RAW264.7 and primary peritoneal macropha...
Testosterone increases: sodium reabsorption, blood pressure, and renal pathology in female spontaneously hypertensive rats on a high sodium diet [0.03%]
睾酮增加：雌性自发性高血压_rat在高钠饮食下的钠再吸收、血压和肾病理变化
Bei Liu,Daniel Ely
Bei Liu
Estrogen (E) and testosterone (T) are important in the sexually dimorphic pattern of blood pressure (BP) development. The goal was to examine the effects of endogenous E and exogenous T in the development of hypertension in female spontaneo...
Preparation and in vitro/in vivo evaluation of vinpocetine elementary osmotic pump system [0.03%]
文诺辛微孔泵渗透体系的制备及其体内外评价研究
Meiying Ning,Yue Zhou,Guojun Chen et al.
Meiying Ning et al.
Preparation and in vitro and in vivo evaluation of vinpocetine (VIN) elementary osmotic pump (EOP) formulations were investigated. A method for the preparation of VIN elementary osmotic pump tablet was obtained by adding organic acid additi...
Toxicokinetics of kava [0.03%]
胡椒毒素的毒代动力学
Anthony Rowe,Lillian Yuan Zhang,Iqbal Ramzan
Anthony Rowe
Kava is traditionally consumed by South Pacific islanders as a drink and became popular in Western society as a supplement for anxiety and insomnia. Kava extracts are generally well tolerated, but reports of hepatotoxicity necessitated an i...
The role of tetrahydrobiopterin and dihydrobiopterin in ischemia/reperfusion injury when given at reperfusion [0.03%]
再灌注时给予四氢生物蝶呤和二氢生物蝶呤对缺血/再灌注损伤的作用
Qian Chen,Elizabeth Eun Jung Kim,Katrina Elio et al.
Qian Chen et al.
Reduced nitric oxide (NO) bioavailability and increased oxidative stress are major factors mediating ischemia/reperfusion (I/R) injury. Tetrahydrobiopterin (BH(4)) is an essential cofactor of endothelial NO synthase (eNOS) to produce NO, wh...
The Effect of an Aqueous Extract of Teucrium polium on Glutathione Homeostasis In Vitro: A Possible Mechanism of Its Hepatoprotectant Action [0.03%]
Teucrium polium水提取物对谷胱甘肽平衡的效应：体外实验及肝保护作用的可能机制研究
Stella Shtukmaster,Predrag Ljubuncic,Arieh Bomzon
Stella Shtukmaster
Background. Teucrium polium is used in Arab traditional medicine to treat liver diseases. Glutathione is an important intracellular antioxidant, and intrahepatic glutathione levels are depleted in liver diseases. Hypothesis and Aim. This in...