Differential downregulation of e-cadherin and desmoglein by epidermal growth factor [0.03%]
表皮生长因子下调E-钙粘素和盘状胶蛋白的作用不同
Miquella G Chavez,Christian A Buhr,Whitney K Petrie et al.
Miquella G Chavez et al.
Modulation of cell : cell junctions is a key event in cutaneous wound repair. In this study we report that activation of the epidermal growth factor (EGF) receptor disrupts cell : cell adhesion, but with different kinetics and fates for the...
A nonimmunosuppressant approach on Asia psoriasis subjects: 5-year followup and 11-year data analysis [0.03%]
亚洲银屑病患者非免疫抑制疗法的五年随访及十一年数据分析
Tony Yuqi Tang
Tony Yuqi Tang
Mono- or combine immunosuppressants are commonly used for psoriasis; however the side effect caused by potent systemic immunosuppressants frequently incurred; moreover the inflammation flares up shortly after immunosuppressants are disconti...
Pierre Vereecken,Frank Cornelis,Nicolas Van Baren et al.
Pierre Vereecken et al.
Many serum biomarkers have been evaluated in melanoma but their clinical significance remains a matter of debate. In this paper, a review of the serum biomarkers for melanoma will be detailed and will be discussed from the point of view of ...
Targeting the Cellular Signaling: BRAF Inhibition and Beyond for the Treatment of Metastatic Malignant Melanoma [0.03%]
针对细胞信号转导：BRAF抑制及其他用于治疗转移性恶性黑色素瘤的方法
Felipe Ades,Otto Metzger-Filho
Felipe Ades
Although advances in cytotoxic treatments have been obtained in several neoplasias, in metastatic melanoma there was no drug able to significantly change the natural history of the disease in the last 30 years. In the last decade, translati...
Multiphoton laser microscopy and fluorescence lifetime imaging for the evaluation of the skin [0.03%]
用于皮肤评估的多光子激光显微镜和荧光寿命成像技术
Stefania Seidenari,Federica Arginelli,Sara Bassoli et al.
Stefania Seidenari et al.
Multiphoton laser microscopy is a new, non-invasive technique providing access to the skin at a cellular and subcellular level, which is based both on autofluorescence and fluorescence lifetime imaging. Whereas the former considers fluoresc...
Ultrasound and 3D Skin Imaging: Methods to Evaluate Efficacy of Striae Distensae Treatment [0.03%]
超声和3D皮肤影像：评估伸展纹疗效的方法
Mariella Bleve,Priscilla Capra,Franca Pavanetto et al.
Mariella Bleve et al.
Background. Over time, the striae rubra develop into striae alba that appear white, flat, and depressed. It is very important to determine the optimum striae management. In order to evaluate the effectiveness of these therapies, objective m...
Pascale Quatresooz,Claudine Piérard-Franchimont,Fanchon Noël et al.
Pascale Quatresooz et al.
During malignant melanoma (MM) progression including incipient metastasis, neoplastic cells follow some specific migration paths inside the skin. In particular, they progress along the dermoepidermal basement membrane, the hair follicles, t...
Nosocomial infections in burned patients in motahari hospital, tehran, iran [0.03%]
伊朗德黑兰Motahari医院烧伤患者的院内感染
Leila Azimi,Abbas Motevallian,Amirmorteza Ebrahimzadeh Namvar et al.
Leila Azimi et al.
Burn patients are at high risk of developing nosocomial infection because of their destroyed skin barrier and suppressed immune system, compounded by prolonged hospitalization and invasive therapeutic and diagnostic procedures. Studies on n...
Smouldering malignant melanoma and metastatic dormancy: an update and review [0.03%]
关于低级别黑色素瘤炎症和转移性休眠的更新及文献回顾
Gérald E Piérard,Claudine Piérard-Franchimont,Marie-Annick Reginster et al.
Gérald E Piérard et al.
The fund of knowledge regarding the versatility of presentation of MM metastases is still quite incomplete. The recent literature pertaining to the current understanding of the mechanisms underlying two special features of MM metastasis is ...
Biomarkers as key contributors in treating malignant melanoma metastases [0.03%]
生物标志物在治疗恶性黑色素瘤转移中的关键作用
Camila Ferreira de Souza,Alice Santana Morais,Miriam Galvonas Jasiulionis
Camila Ferreira de Souza
Melanoma is a human neurocristopathy associated with developmental defects in the neural crest-derived epidermal melanocytes. At the present time, at least three hypotheses were identified that may explain melanoma aetiology, as follows: (1...