Demarcation of informative chromosomes in tropical sweet corn inbred lines using microsatellite DNA markers [0.03%]
采用微卫星DNA标记鉴定热带甜玉米自交系的富含信息染色体区域
Pedram Kashiani,Ghizan Saleh,Jothi Malar Panandam et al.
Pedram Kashiani et al.
A study of genetic variation among 10 pairs of chromosomes extracted from 13 tropical sweet corn inbred lines, using 99 microsatellite markers, revealed a wide range of genetic diversity. Allelic richness and the number of effective alleles...
Identification of novel single nucleotide polymorphisms in the DGAT1 gene of buffaloes by PCR-SSCP [0.03%]
应用PCR-SSCP技术鉴定水牛DGAT1基因的新单核苷酸多态性
Ashwin A Raut,Anil Kumar,Sheo N Kala et al.
Ashwin A Raut et al.
Diacylglycerol O-acyltransferase 1 (DGAT1) is a microsomal enzyme that catalyzes the final step of triglyceride synthesis. The DGAT1 gene is a strong functional candidate for determining milk fat content in cattle. In this work, we used PCR...
Genetic characterization of Bhutanese native chickens based on an analysis of Red Junglefowl (Gallus gallus gallus and Gallus gallus spadecieus), domestic Southeast Asian and commercial chicken lines (Gallus gallus domesticus) [0.03%]
基于环颈野鸡、东南亚家养禽和商业品种全基因组重测序解析不丹本地鸡的遗传特性
Nedup Dorji,Monchai Duangjinda,Yupin Phasuk
Nedup Dorji
The genetic diversity of Bhutanese chickens needs to be understood in order to develop a suitable conservation strategy for these birds in Bhutan. In this, work, we used microsatellite markers to examine the genetic diversity of Bhutanese c...
Prevalence of 185delAG and 5382insC mutations in BRCA1, and 6174delT in BRCA2 in women of Ashkenazi Jewish origin in southern Brazil [0.03%]
巴西南部阿什肯纳兹犹太人妇女BRCA1基因185delAG和5382insC突变及BRCA2基因6174delT突变的流行病学研究
Crisle Vignol Dillenburg,Isabel Cristina Bandeira,Taiana Valente Tubino et al.
Crisle Vignol Dillenburg et al.
Certain mutations in BRCA1 and BRCA2 genes are frequent in the Ashkenazi Jewish population. Several factors contribute to this increased frequency, including consanguineous marriages and an event known as a "bottleneck", which occurred in t...
Prevalence of α-thalassemia 3.7 kb deletion in the adult population of Rio Grande do Norte, Brazil [0.03%]
巴西里约 grande do norte州成年人α-地中海贫血3.7kb缺失的流行率
Gustavo Henrique de Medeiros Alcoforado,Christiane Medeiros Bezerra,Telma Maria Araújo Moura Lemos et al.
Gustavo Henrique de Medeiros Alcoforado et al.
α-Thalassemia, arising from a defect in α-globin chain synthesis, is often caused by deletions involving one or both of the α-genes on the same allele. With the aim of investigating the prevalence of α-thalassemia 3.7 kb deletion in the...
Association of a serotonin transporter gene (SLC6A4) 5-HTTLPR polymorphism with body mass index categories but not type 2 diabetes mellitus in Mexicans [0.03%]
五-羟色胺转运蛋白基因(SLC6A4)5-HTTLPR多态性与墨西哥人体质指数分类相关但与2型糖尿病无关
Valeria Peralta-Leal,Evelia Leal-Ugarte,Juan P Meza-Espinoza et al.
Valeria Peralta-Leal et al.
The serotonergic system has been hypothesized to contribute to the biological susceptibility to type 2 diabetes mellitus (T2DM) and body-mass index (BMI) categories. We investigate a possible association of 5-HTTLPR polymorphism (L and S al...
Paulo A Otto,Andréa R V R Horimoto
Paulo A Otto
Accurate estimates of the penetrance rate of autosomal dominant conditions are important, among other issues, for optimizing recurrence risks in genetic counseling. The present work on penetrance rate estimation from pedigree data considers...
Association of serum lipid components and obesity with genetic ancestry in an admixed population of elderly women [0.03%]
血清脂质成分、肥胖与老年人群遗传祖先的相关性研究
Tulio C Lins,Alause S Pires,Roberta S Paula et al.
Tulio C Lins et al.
The prevalence of metabolic disorders varies among ethnic populations and these disorders represent a critical health care issue for elderly women. This study investigated the correlation between genetic ancestry and body composition, metab...
Differential allelic expression of IL13 and CSF2 genes associated with asthma [0.03%]
与哮喘相关的IL13和CSF2基因的等位基因差异表达
Jana Burkhardt,Holger Kirsten,Grit Wolfram et al.
Jana Burkhardt et al.
An important area of genetic research is the identification of functional mechanisms in polymorphisms associated with diseases. A highly relevant functional mechanism is the influence of polymorphisms on gene expression levels (differential...
Clinical and molecular analysis of the enamelin gene ENAM in Colombian families with autosomal dominant amelogenesis imperfecta [0.03%]
哥伦比亚遗传性 autosomal dominant amelogenesis imperfecta 家族的临床和分子分析
Sandra Gutiérrez,Diana Torres,Ignacio Briceño et al.
Sandra Gutiérrez et al.
In this study, we analyzed the phenotype, clinical characteristics and presence of mutations in the enamelin gene ENAM in five Colombian families with autosomal dominant amelogenesis imperfecta (ADAI). 22 individuals (15 affected and seven ...